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View Structure Prediction Details

Protein: ATG1
Organism: Saccharomyces cerevisiae
Length: 897 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG1.

Description E-value Query
Range
Subject
Range
ATG1_YEAS7 - Serine/threonine-protein kinase ATG1 OS=Saccharomyces cerevisiae (strain YJM789) GN=ATG1 PE=3 SV=1
ATG1 - Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targ...
ATG1_YEAST - Serine/threonine-protein kinase ATG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG...
gi|207345486 - gi|207345486|gb|EDZ72296.1| YGL180Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407122 - gi|190407122|gb|EDV10389.1| protein kinase [Saccharomyces cerevisiae RM11-1a]
0.0 [1..897] [1..897]
ATG1_PICAN - Serine/threonine-protein kinase ATG1 OS=Pichia angusta GN=ATG1 PE=3 SV=1
ATG1_PICAN - Serine/threonine-protein kinase ATG1 OS=Pichia angusta GN=ATG1 PE=3 SV=1
0.0 [14..896] [3..800]
gi|238031362, gi... - gi|254568910|ref|XP_002491565.1| Protein serine/threonine kinase required for vesicle formation in a...
ATG1_PICPA - Serine/threonine-protein kinase ATG1 OS=Komagataella pastoris GN=ATG1 PE=3 SV=1
jgi|Picpa1|37626... - null
0.0 [17..893] [2..787]
ppk36 - serine /threonine protein kinase Ppk36
ATG1_SCHPO - Serine/threonine-protein kinase atg1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg1 ...
0.0 [15..897] [5..811]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..693] [2..615]
gi|9845487, gi|1... - ref|NP_059672.1| MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens], gi|1749794|...
0.0 [4..693] [2..615]
Atg1-PA - The gene Autophagy-specific gene 1 is referred to in FlyBase by the symbol Dmel\Atg1 (CG10967, FBgn0...
0.0 [21..891] [4..824]
gi|148225752, gi... - gi|19698204|dbj|BAB86594.1| serine/threonine kinase [Xenopus laevis], gi|148225752|ref|NP_001080425....
0.0 [2..692] [35..646]
gi|3172111 - gi|3172111|dbj|BAA28663.1| HrPOPK-1 [Halocynthia roretzi]
0.0 [15..753] [5..687]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDIKNKDHT TSVNHNLMAS AGNYTAEKEI GKGSFATVYR GHLTSDKSQH VAIKEVSRAK  60
   61 LKNKKLLENL EIEI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [88-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIDCERTSTD FYLIMEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 384.9794
Match: 1fotA_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [75-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AILKKIKHPH IVG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [105-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CALGDLTFLL KRRKELMENH PLLRTVFEKY PPPSENHNGL HRAFVLSYLQ QLASALKFLR  60
   61 SKNLVHRDIK PQNLLLSTPL IGYHDSKSFH ELGFVGIYNL PILKIADFGF ARFLPNTSLA 120
  121 ETLCGSPLYM APEILNYQKY NAKADLWSVG TVVFEMCCGT PPFRASNHLE LFKKIKRAND 180
  181 VITFPSYCNI EPELKELICS LLTFDPAQRI GFEEFFANKV VNEDLSSYEL EDDLPELESK 240
  241 SKGIVESNMF VSEYLSKQPK SPNSNLAGHQ SMADNPAELS DALKNSNILT APAVKTDHTQ 300
  301 AVDKKASNNK YHNSLVSDRS FER

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 384.9794
Match: 1fotA_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [428-897]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYVVVEKKSV EVNSLADEVA QAGFNPNPIK HPTSTQNQNV LLNEQFSPNN QQYFQNQGEN  60
   61 PRLLRATSSS SGGSDGSRRP SLVDRRLSIS SLNPSNALSR ALGIASTRLF GGANQQQQQQ 120
  121 QITSSPPYSQ TLLNSQLFHE LTENIILRID HLQHPETLKL DNTNIVSILE SLAAKAFVVY 180
  181 SYAEVKFSQI VPLSTTLKGM ANFENRRSMD SNAIAEEQDS DDAEEEDETL KKYKEDCLST 240
  241 KTFGKGRTLS ATSQLSATFN KLPRSEMILL CNEAIVLYMK ALSILSKSMQ VTSNWWYESQ 300
  301 EKSCSLRVNV LVQWLREKFN ECLEKADFLR LKINDLRFKH ASEVAENQTL EEKGSSEEPV 360
  361 YLEKLLYDRA LEISKMAAHM ELKGENLYNC ELAYATSLWM LETSLDDDDF TNAYGDYPFK 420
  421 TNIHLKSNDV EDKEKYHSVL DENDRIIIRK YIDSIANRLK ILRQKMNHQN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [678-897]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSQLSATFN KLPRSEMILL CNEAIVLYMK ALSILSKSMQ VTSNWWYESQ EKSCSLRVNV  60
   61 LVQWLREKFN ECLEKADFLR LKINDLRFKH ASEVAENQTL EEKGSSEEPV YLEKLLYDRA 120
  121 LEISKMAAHM ELKGENLYNC ELAYATSLWM LETSLDDDDF TNAYGDYPFK TNIHLKSNDV 180
  181 EDKEKYHSVL DENDRIIIRK YIDSIANRLK ILRQKMNHQN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle