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View Structure Prediction Details

Protein: AIM14
Organism: Saccharomyces cerevisiae
Length: 570 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIM14.

Description E-value Query
Range
Subject
Range
gi|17384016 - gi|17384016|emb|CAC87256.1| NADPH oxidase [Nicotiana tabacum]
0.0 [40..568] [371..962]
RBOHA_SOLTU - Respiratory burst oxidase homolog protein A OS=Solanum tuberosum GN=RBOHA PE=1 SV=1
0.0 [40..568] [372..963]
gi|8131846, gi|8... - gi|8131890|gb|AAF73124.1|AF148534_1 whitefly-induced gp91-phox [Lycopersicon esculentum], gi|8131846...
0.0 [43..568] [339..938]
RBOHF_ARATH - Respiratory burst oxidase homolog protein F OS=Arabidopsis thaliana GN=RBOHF PE=1 SV=1
0.0 [40..568] [360..944]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [40..568] [360..944]

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Predicted Domain #1
Region A:
Residues: [1-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESPLITLV KRHSETHFAN IKYGYYVLII SLVYLIGLAL LRAFGRRTPS RSSSAFKNKI  60
   61 IYRLYDIDPA IHLGILFFAV LIPFYYHYSL TTQSTVYLKR LGRLSYALIP LNLFLTLRPN 120
  121 WFLRKNCTYT DFIPFHKWFS RIITVIGLLH GIFFIIKWAI DDNVSLKQKL ILKTF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [176-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFAGFIISIL VLFLLICSIG PMRRYNYRLF YIVHNLVNVA FILLTPIHSR PG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.373 a.4.1 Homeodomain-like
View Download 0.385 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.564 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.637 a.50.1 Anaphylotoxins (complement system)
View Download 0.370 a.4.1 Homeodomain-like
View Download 0.334 a.161.1 beta-catenin-interacting protein ICAT
View Download 0.327 f.13.1 Family A G protein-coupled receptor-like
View Download 0.323 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.316 a.16.1 S15/NS1 RNA-binding domain
View Download 0.316 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.302 a.4.1 Homeodomain-like
View Download 0.281 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.279 a.4.1 Homeodomain-like
View Download 0.266 a.4.1 Homeodomain-like
View Download 0.257 a.17.1 p8-MTCP1
View Download 0.254 a.4.5 "Winged helix" DNA-binding domain
View Download 0.246 a.4.1 Homeodomain-like
View Download 0.243 a.5.2 UBA-like
View Download 0.237 a.118.8 TPR-like
View Download 0.228 a.4.1 Homeodomain-like
View Download 0.222 a.85.1 Hemocyanin, N-terminal domain
View Download 0.222 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.211 a.3.1 Cytochrome c
View Download 0.211 a.135.1 Tetraspanin
View Download 0.209 a.2.7 tRNA-binding arm

Predicted functions:

Term Confidence Notes
transporter activity 0.629864849462794 bayes_pls_golite062009
transmembrane transporter activity 0.622501423809131 bayes_pls_golite062009
ion transmembrane transporter activity 0.61858000771821 bayes_pls_golite062009
cation transmembrane transporter activity 0.614636573821539 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.569065361315241 bayes_pls_golite062009
substrate-specific transporter activity 0.557390564903452 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.438985705028009 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.438562910643884 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.432885404990755 bayes_pls_golite062009
catalytic activity 0.349353660965659 bayes_pls_golite062009
binding 0.0102629993652836 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [228-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKFPFLLLNC TLLFIHIINR IVFAKSLMIL NKNANYSKTN LVHVRLPRAI LPDYFEPGSH  60
   61 IRISPYRRIN PLYWLLPSHP YTIASLAEDN SIDLIIKETS TAEPGSQIES LRSNPKSFHL 120
  121 DQEKTYTLIN SY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1cnf__
Description: Nitrate reductase core domain; Nitrate reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.687312782648907 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [360-570]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSVPEECYS QGTNIAIICG GSGISFALPL FRHFFNKENV KYLKMIWLIK DYSEYELVLD  60
   61 YLKTNGLTFE KKLSNNKRIS VFISGEYTAE TRLDEITTNI DDENSEYEMG SFNNEDEDLS 120
  121 ISNFNSENAD SNDNTPETSH SPTKENGSMI EVKSKHSFTL SNELKSFNNE SAQVNQNETW 180
  181 LFSCGPPSLL QLSKKYCNDE RINFVCETYG L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1cnf__
Description: Nitrate reductase core domain; Nitrate reductase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle