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View Structure Prediction Details

Protein: AIM14
Organism: Saccharomyces cerevisiae
Length: 570 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIM14.

Description E-value Query
Range
Subject
Range
gi|17384016 - gi|17384016|emb|CAC87256.1| NADPH oxidase [Nicotiana tabacum]
0.0 [40..568] [371..962]
RBOHA_SOLTU - Respiratory burst oxidase homolog protein A OS=Solanum tuberosum GN=RBOHA PE=1 SV=1
0.0 [40..568] [372..963]
gi|8131846, gi|8... - gi|8131890|gb|AAF73124.1|AF148534_1 whitefly-induced gp91-phox [Lycopersicon esculentum], gi|8131846...
0.0 [43..568] [339..938]
RBOHF_ARATH - Respiratory burst oxidase homolog protein F OS=Arabidopsis thaliana GN=RBOHF PE=1 SV=1
0.0 [40..568] [360..944]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [40..568] [360..944]

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Predicted Domain #1
Region A:
Residues: [1-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESPLITLV KRHSETHFAN IKYGYYVLII SLVYLIGLAL LRAFGRRTPS RSSSAFKNKI  60
   61 IYRLYDIDPA IHLGILFFAV LIPFYYHYSL TTQSTVYLKR LGRLSYALIP LNLFLTLRPN 120
  121 WFLRKNCTYT DFIPFHKWFS RIITVIGLLH GIFFIIKWAI DDNVSLKQKL ILKTF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [176-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFAGFIISIL VLFLLICSIG PMRRYNYRLF YIVHNLVNVA FILLTPIHSR PG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transporter activity 0.629864849462794 bayes_pls_golite062009
transmembrane transporter activity 0.622501423809131 bayes_pls_golite062009
ion transmembrane transporter activity 0.61858000771821 bayes_pls_golite062009
cation transmembrane transporter activity 0.614636573821539 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.569065361315241 bayes_pls_golite062009
substrate-specific transporter activity 0.557390564903452 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.438985705028009 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.438562910643884 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.432885404990755 bayes_pls_golite062009
catalytic activity 0.349353660965659 bayes_pls_golite062009
binding 0.0102629993652836 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [228-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKFPFLLLNC TLLFIHIINR IVFAKSLMIL NKNANYSKTN LVHVRLPRAI LPDYFEPGSH  60
   61 IRISPYRRIN PLYWLLPSHP YTIASLAEDN SIDLIIKETS TAEPGSQIES LRSNPKSFHL 120
  121 DQEKTYTLIN SY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1cnf__
Description: Nitrate reductase core domain; Nitrate reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.687312782648907 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [360-570]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSVPEECYS QGTNIAIICG GSGISFALPL FRHFFNKENV KYLKMIWLIK DYSEYELVLD  60
   61 YLKTNGLTFE KKLSNNKRIS VFISGEYTAE TRLDEITTNI DDENSEYEMG SFNNEDEDLS 120
  121 ISNFNSENAD SNDNTPETSH SPTKENGSMI EVKSKHSFTL SNELKSFNNE SAQVNQNETW 180
  181 LFSCGPPSLL QLSKKYCNDE RINFVCETYG L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1cnf__
Description: Nitrate reductase core domain; Nitrate reductase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle