YRC Public Data Repository - Protein Structure Prediction

Protein:	SLD3
Organism:	Saccharomyces cerevisiae
Length:	668 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLD3.

Description	E-value	Query Range	Subject Range
SLD3_SCHPO - DNA replication regulator sld3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sld3 PE=1 S... sld3 - DNA replication pre-initiation complex subunit Sld3	557.0	[0..159]	[619..213]
sld3 - DNA replication pre-initiation complex subunit Sld3 SLD3_SCHPO - DNA replication regulator sld3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sld3 PE=1 S...	556.0	[0..159]	[619..213]
gi\|1945296, gi\|1... - gi\|1945296\|emb\|CAA96820.1\| unnamed protein product [Saccharomyces cerevisiae], gi\|1310711\|emb\|CAA662...	280.0	[0..492]	[668..1]
gi\|44984451, gi\|... - gi\|45198500\|ref\|NP_985529.1\| AFL019Cp [Ashbya gossypii ATCC 10895], gi\|44984451\|gb\|AAS53353.1\| AFL01... gi\|44984451 - gi\|44984451\|gb\|AAS53353.1\| AFL019Cp [Ashbya gossypii ATCC 10895]	257.0	[0..6]	[665..8]
gi\|49525590, gi\|... - gi\|50287707\|ref\|XP_446283.1\| unnamed protein product [Candida glabrata], gi\|49525590\|emb\|CAG59207.1\|... gi\|49525590 - gi\|49525590\|emb\|CAG59207.1\| unnamed protein product [Candida glabrata]	237.0	[0..1]	[665..1]
gi\|49644702, gi\|... - gi\|50311085\|ref\|XP_455566.1\| unnamed protein product [Kluyveromyces lactis], gi\|49644702\|emb\|CAG9827... gi\|49644702\|emb\|... - unnamed protein product [Kluyveromyces lactis NRRL Y-1140]	229.0	[0..4]	[665..8]
gi\|50423939, gi\|... - gi\|50423939\|ref\|XP_460554.1\| hypothetical protein DEHA0F04763g [Debaryomyces hansenii CBS767], gi\|49...	85.0	[0..142]	[648..172]
gi\|114197200, gi... - gi\|115491425\|ref\|XP_001210340.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	82.0	[0..141]	[606..255]
gi\|90298134, gi\|... - gi\|90298134\|gb\|EAS27765.1\| hypothetical protein CIMG_08969 [Coccidioides immitis RS], gi\|119173974\|r...	71.0	[0..156]	[624..154]
gi\|40746658, gi\|... - gi\|67518126\|ref\|XP_658825.1\| hypothetical protein AN1221.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	67.0	[0..252]	[603..395]

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Predicted Domain #1

Region A:
Residues: [1-490]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METWEVIASV KEATKGLDLS LDHPLIIKSE DVPSNILQLL QQKNRRQLKH ICMKSRKEYF  60
   61 LLEEYGPGFW VKWPYNYFNG YSLPERRTEV VTTVERERAK RETLKTWDEL KFKELLHLWS 120
  121 EEPKGSCKLE KDKDLKLDMN PPDMKGESKI NDYYSDPKEY IESKYYDALF SIHTPLAYFV 180
  181 KSNLVRLKNT CRTKYGSDSY KIAYQAMLQK FLLSIVQFKD RHDNRLLLEP FSSPIADEKR 240
  241 KNCLTKFVIQ DENKNSSTIA DLCVVLKSRE IKLQILLLLE IIGLNDLDWN FRDFEKKYKL 300
  301 KLKKRSLNLT KKGLVRRRSK KKTSEKDKGI ERITTSLDYC EQLDLYLDRA CILDILLSSE 360
  361 TPNPDAIEAS NGTIQEHKKN ILDKSKEASL VGFINYVLIP YFNKKVPHAV EFIIQKLKGP 420
  421 SMRPKRALKK VNDSTNVSSP NTVETYNRLS TSQRASRSSI INSVPSSPAL RRVDANLFSR 480
  481 KSIASPTPEL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [491-668]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNSRTNSNLN EFLESETRSL KRPSQLGRTK SDLTMNHLQK RQFSVSDLST TRVPNSSTIT  60
   61 LKTPFSHSTI NAYKTMNNSF RRVGKRKDIN ETIRLHERVD SEENVQVQAT PAVKKRTVTP 120
  121 NKKAQLQSII ESPLNFKDDD THEGRKNTSN ITSTPTNKPP ENSSKRRVRR RLFAPEST

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.489	N/A	N/A	d.3.1	Cysteine proteinases

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits