YRC Public Data Repository - Protein Structure Prediction

Protein:	LSG1
Organism:	Saccharomyces cerevisiae
Length:	640 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LSG1.

Description	E-value	Query Range	Subject Range
gi\|44984428 - gi\|44984428\|gb\|AAS53330.1\| AFL042Cp [Ashbya gossypii ATCC 10895] gi\|44984428, gi\|... - gi\|45198477\|ref\|NP_985506.1\| AFL042Cp [Ashbya gossypii ATCC 10895], gi\|44984428\|gb\|AAS53330.1\| AFL04...	385.0	[0..1]	[616..1]
gi\|49527251 - gi\|49527251\|emb\|CAG60891.1\| unnamed protein product [Candida glabrata] gi\|50291015, gi\|... - gi\|50291015\|ref\|XP_447940.1\| unnamed protein product [Candida glabrata], gi\|49527251\|emb\|CAG60891.1\|...	370.0	[0..20]	[616..20]
gi\|49644518 - gi\|49644518\|emb\|CAG98090.1\| KLLA0F06666p [Kluyveromyces lactis] gi\|49644518, gi\|... - gi\|50310721\|ref\|XP_455382.1\| unnamed protein product [Kluyveromyces lactis], gi\|49644518\|emb\|CAG9809...	364.0	[0..1]	[611..1]
LSG1_SCHPO - Large subunit GTPase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lsg1 PE=3 SV=1 SPAC3F10.16c - GTP binding protein, HSR1-related	339.0	[0..22]	[634..5]
gi\|85099145 - gi\|85099145\|ref\|XP_960724.1\| hypothetical protein NCU04166 [Neurospora crassa OR74A] gi\|32405786, gi\|... - gi\|32405786\|ref\|XP_323506.1\| hypothetical protein ( (AL513445) conserved hypothetical protein [Neuro...	334.0	[0..21]	[622..4]
LSG12_ARATH - GTPase LSG1-2 OS=Arabidopsis thaliana GN=LSG1-2 PE=1 SV=1	325.0	[0..26]	[614..6]
gi\|50418683, gi\|... - gi\|50418683\|ref\|XP_457861.1\| hypothetical protein DEHA0C04664g [Debaryomyces hansenii CBS767], gi\|49...	325.0	[0..7]	[612..15]
gi\|68223734, gi\|... - gi\|68223734\|emb\|CAJ01966.1\| GTPase, putative [Leishmania major], emb\|CAC32261.1\| MMR_HSR1 GTP-bindin... gi\|157863947 - gi\|157863947\|ref\|XP_001687523.1\| GTPase [Leishmania major strain Friedlin]	321.0	[0..10]	[634..12]
gi\|46433895, gi\|... - gi\|68487240\|ref\|XP_712503.1\| hypothetical protein CaO19.3463 [Candida albicans SC5314], gi\|68487179\|... orf19.3463, orf1... - orf19.3463 CGDID:CAL0005034 Assembly 19, Contig19-10177 (18718, 20772) CDS, translated using codon t...	308.0	[0..1]	[617..9]
gi\|114555589 - gi\|114555589\|ref\|XP_001169466.1\| PREDICTED: guanine nucleotide binding protein-like 2 (nucleolar) is...	306.0	[0..11]	[557..16]

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Predicted Domain #1

Region A:
Residues: [1-102]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPKEAPKKW KAPKGPKPTH RKNKNKLELG RAIKYARQKE NAIEYLPDGE MRFTTDKHEA  60
   61 NWVKLRSVTQ ESALDEFLST AALADKDFTA DRHSNVKIIR MD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [103-321]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGNDSATSQG FSMTNEQRGN LNAKQRALAK DLIVPRRPEW NEGMSKFQLD RQEKEAFLEW  60
   61 RRKLAHLQES NEDLLLTPFE RNIEVWKQLW RVVERSDLVV QIVDARNPLL FRSVDLERYV 120
  121 KESDDRKANL LLVNKADLLT KKQRIAWAKY FISKNISFTF YSALRANQLL EKQKEMGEDY 180
  181 REQDFEEADK EGFDADEKVM EKVKILSIDQ LEELFLSKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.522879
Match:	1g7rA
Description:	Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [322-512]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNEPLLPPLP GQPPLINIGL VGYPNVGKSS TINSLVGAKK VSVSSTPGKT KHFQTIKLSD  60
   61 SVMLCDCPGL VFPNFAYNKG ELVCNGVLPI DQLRDYIGPA GLVAERIPKY YIEAIYGIHI 120
  121 QTKSRDEGGN GDIPTAQELL VAYARARGYM TQGYGSADEP RASRYILKDY VNGKLLYVNP 180
  181 PPHLEDDTPY T

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.0
Match:	1egaA
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [513-640]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REECEEFNKD LYVFDRLPDT RKEQVQNAAK AKGIDIVDLA RDLNQLTFSA HTGGDTQKEA  60
   61 KSVTHGGKQA ALYNAAEDLD RDFFKMNNVE GRLSTPFHKV QNSSAGKRHN KKNKSKNAKS 120
  121 KVFSIENN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.0
Match:	1egaA
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits