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View Structure Prediction Details

Protein: GEP7
Organism: Saccharomyces cerevisiae
Length: 287 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GEP7.

Description E-value Query
Range
Subject
Range
GEP7_YEAST - Genetic interactor of prohibitin 7, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
GEP7 - Protein of unknown function; null mutant exhibits a respiratory growth defect and synthetic interact...
0.0 [1..287] [1..287]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLSNVKIFR LKSHRAFRIG PMIKAVAGNL LVKRFYQPKL ERIPPASLLL KQKIRLAQNG  60
   61 STTSTENPIS FSQTMSEIFS VLQPSAPDLD EDETSGLKRD HLLTERLNNG ELGVIMNKFF 120
  121 NPSSTHNNQL IDTNILLQNF PKLSGNDLDL LDFAINEKMR GNWNDLKQDF IQLWYYKSFG 180
  181 FLGPRTQFVL TNSSPSVRSQ FLKLPFIEYN WFLLQNNKNA NILPADVQNV VKVFHLDDKR 240
  241 FTWKSIDPFS KAIISFVVFV SIYVWLDESA KQKTKELPAQ KSTVISE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [145-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNDLDLLDFA INEKMRGNWN DLKQDFIQLW YYKSFGFLGP RTQFVLTNSS PSVRSQFLKL  60
   61 PFIEYNWFLL QNNKNANILP ADVQNVVKVF HLDDKRFTWK SIDPFSKAII SFVVFVSIYV 120
  121 WLDESAKQKT KELPAQKSTV ISE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.35
Match: 1occD
Description: Mitochondrial cytochrome c oxidase subunit IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 0.200883452155884 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.161136760124421 bayes_pls_golite062009
binding 0.118712393901925 bayes_pls_golite062009
oxidoreductase activity 0.105855344322413 bayes_pls_golite062009
cytochrome-c oxidase activity 0.104705673375264 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 0.104705673375264 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.104705673375264 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle