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View Structure Prediction Details

Protein: SCW11
Organism: Saccharomyces cerevisiae
Length: 542 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCW11.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 8.0E-90 [260..540] [1..325]
gi|16903144 - gi|16903144|gb|AAL30426.1|AF435089_1 beta-1,3-glucanase [Prunus persica]
 2.0E-88 [249..540] [3..332]
gi|4883425 - gi|4883425|emb|CAA10287.2| glucan-endo-1,3-beta-glucosidase [Cicer arietinum]
 2.0E-84 [259..540] [12..337]
gi|170304 - gi|170304|gb|AAA34103.1| PR2
 8.0E-84 [266..540] [16..332]

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Predicted Domain #1
Region A:
Residues: [1-281] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISPISFLSS LLCLTYLTSA LPILPKREVV TRVHTASTTN VVTDFYSTTT EVVIAPTVEF  60
   61 LISDSVTFTT TLIPQGVNPT AEPTTTITKV LLKKAEMSTS SQPTSTLQPS TIPQSTSSFQ 120
  121 AESTLQAVST QQTAMSVSAG TSEDVQQLAT TSTSISSSPS PTTTSTSTQN IVSGVGEANV 180
  181 EGNTQSQHHS YQAAATSTLN QQTSTSIASQ ESTESTNTPT SSSTSSSTSS STSSSTSSST 240
  241 SSSTSSSTSS STSSSTSSTQ ETAATTSEGS SSSSAAITSS P

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.09
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [282-346] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAIAYSPYND DGSCKSADAV SSDLTLIKSK GISKIRVYGT DCNSFETVQP AAVKLGIKIN  60
   61 QGLYI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [367-379] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNGWDVFDFI TVG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [409-415] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSGQITT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ghsA_
Description: Plant beta-glucanases
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [347-366] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSGVDSIDD SVTTLIQYGQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [380-408] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEAINNGWCS VSDLISKISS VKSKLSEAG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [416-440] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEPPVSFENN PDLCKKSDID FVGIN

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [458-477] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKGQVELIQG VCGTSNVFVT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ghsA_
Description: Plant beta-glucanases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on glycosyl bonds 5.36248919165223 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.11319792356479 bayes_pls_golite062009
glucosidase activity 3.69195576225095 bayes_pls_golite062009
beta-glucosidase activity 3.14931331494576 bayes_pls_golite062009
chitinase activity 2.45357334610104 bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity 2.19754833026935 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
hydrolase activity 1.53559572084132 bayes_pls_golite062009
hexosaminidase activity 1.26857012744249 bayes_pls_golite062009
receptor binding 0.709153600415243 bayes_pls_golite062009
carbohydrate binding 0.45065632894721 bayes_pls_golite062009
binding 0.391406996198514 bayes_pls_golite062009
signal transducer activity 0.204404145728779 bayes_pls_golite062009
molecular transducer activity 0.204404145728779 bayes_pls_golite062009
pattern binding 0.113396113487931 bayes_pls_golite062009
polysaccharide binding 0.10746671207581 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [441-457] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHAYFDTSAS AETAGTF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [478-542] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETGYPSSGIQ NGGNIPSTAN QITAVQNILN EMDLDVTILS TYNDYWKAPG DYGIEQSFGV  60
   61 IEYFP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.39794
Match: 1ghsA_
Description: Plant beta-glucanases
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle