YRC Public Data Repository - Protein Structure Prediction

Protein:	SAD1
Organism:	Saccharomyces cerevisiae
Length:	448 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAD1.

Description	E-value	Query Range	Subject Range
gi\|13926071 - gi\|13926071\|gb\|AAK49524.1\|AF353989_1 U4/U6.U5 tri-snRNP-associated 65 kDa protein [Homo sapiens]	3.0E-95	[1..448]	[70..556]
SNUT2_MOUSE - U4/U6.U5 tri-snRNP-associated protein 2 OS=Mus musculus GN=Usp39 PE=1 SV=2	2.0E-94	[1..448]	[69..555]
gi\|33589748, gi\|... - gi\|33589748\|gb\|AAQ22640.1\| At4g22410/F7K2_7 [Arabidopsis thaliana], gi\|22328871\|ref\|NP_193966.2\| ubi...	5.0E-85	[2..448]	[44..509]
CE20660 - ubiquitin protease status:Partially_confirmed UniProt:O44787 protein_id:AAD34652.1	1.0E-84	[2..445]	[107..584]
ubp10 - ubiquitin C-terminal hydrolase Ubp10 UBP10_SCHPO - Probable mRNA-splicing protein ubp10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ubp10...	2.0E-75	[1..446]	[29..500]
SAD1 - Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRN... SAD1_YEAST - Pre-mRNA-splicing factor SAD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAD1 PE=1 ...	1.0E-74	[1..448]	[1..448]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVDNKRRHS EDELKQEAVK KIKSQEPNYA YLETVVREKL DFDSEKICCI TLSPLNVYCC  60
   61 LVCGHYYQGR HEKSPAFIHS IDENHHVFLN LTSLKFYMLP QNVQILHDGE VQLLNSIKFA 120
  121 AYPT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [125-448]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YCPKDLEDFP RQCFDLSNRT YLNGFIGFTN AATYDYAHSV LLLISHMVPV RDHFLLNHFD  60
   61 NQGEFIKRLS ICVKKIWSPK LFKHHLSVDD FVSYLKVREG LNLNPIDPRL FLLWLFNKIC 120
  121 SSSNDLKSIL NHSCKGKVKI AKVENKPEAS ESVTGKVIVK PFWVLTLDLP EFSPFEDGNS 180
  181 VDDLPQINIT KLLTKFTKSR SSSTSTVFEL TRLPQFLIFH FNRFDRNSDH PVKNRNQTLV 240
  241 EFSSELEILH VKYRLKANVV HVVIKQPSTD GNAFNGDEKS HWITQLYDNK SEKWIEIDGI 300
  301 NTTEREAELL FLKETFIQVW EKQE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits