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View Structure Prediction Details

Protein: MOB2
Organism: Saccharomyces cerevisiae
Length: 287 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MOB2.

Description E-value Query
Range		 Subject
Range
MOB2 - Component of the RAM signaling network, that activates the Cbk1p kinase, thereby facilitating the Ac...
gi|190406540 - gi|190406540|gb|EDV09807.1| maintenance of ploidy protein MOB2 [Saccharomyces cerevisiae RM11-1a]
MOB2_YEAST - CBK1 kinase activator protein MOB2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MOB2 ...
 0.0 [1..287] [1..287]
gi|2832633, gi|7... - pir||T04426 hypothetical protein T18B16.20 - Arabidopsis thaliana, gi|7268700|emb|CAB78907.1| putat...
 4.0E-92 [56..278] [1171..1401]
MOL1B_PONPY - Mps one binder kinase activator-like 1B - Pongo pygmaeus (Orangutan)
gi|55606148 - gi|55606148|ref|XP_515735.1| PREDICTED: Mob4B protein isoform 4 [Pan troglodytes]
tr|G1SUR2|G1SUR2... - Uncharacterized protein OS=Oryctolagus cuniculus GN=MOB1A PE=4 SV=2
MOB1A_MOUSE - MOB kinase activator 1A OS=Mus musculus GN=Mob1a PE=2 SV=3
MOBKL1B - MOB1, Mps One Binder kinase activator-like 1B (yeast)
MOB1A_PONAB - MOB kinase activator 1A OS=Pongo abelii GN=MOB1A PE=2 SV=3
MOB1A_RAT - MOB kinase activator 1A OS=Rattus norvegicus GN=Mob1a PE=2 SV=3
gi|111305145, gi... - gi|76628940|ref|XP_871266.1| PREDICTED: similar to Mob4B protein [Bos taurus], gi|115496426|ref|NP_0...
gi|73980517 - gi|73980517|ref|XP_852858.1| PREDICTED: similar to Mob4B protein isoform 1 [Canis familiaris]
 6.0E-90 [68..278] [5..211]
CE18580 - status:Confirmed UniProt:Q7JLW3 protein_id:CAA93647.1
 2.0E-86 [3..275] [22..294]

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Predicted Domain #1
Region A:
Residues: [1-64] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFFNFKAFG RNSKKNKNQP LNVAQPPAMN TIYSSPHSSN SRLSLRNKHH SPKRHSQTSF  60
   61 PAQK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [65-287] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STPQSQQLTS TTPQSQQQEA SERSESQQIM FLSEPFVRTA LVKGSFKTIV QLPKYVDLGE  60
   61 WIALNVFEFF TNLNQFYGVV AEYVTPDAYP TMNAGPHTDY LWLDANNRQV SLPASQYIDL 120
  121 ALTWINNKVN DKNLFPTKNG LPFPQQFSRD VQRIMVQMFR IFAHIYHHHF DKIVHLSLEA 180
  181 HWNSFFSHFI SFAKEFKIID RKEMAPLLPL IESFEKQGKI IYN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 112.142668
Match: PF03637
Description: Mob1/phocein family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.92301852481284 bayes_pls_golite062009
kinase regulator activity 1.89112613830997 bayes_pls_golite062009
enzyme regulator activity 1.85961781963242 bayes_pls_golite062009
protein binding 1.70532605681329 bayes_pls_golite062009
protein kinase regulator activity 1.22656624834768 bayes_pls_golite062009
enzyme activator activity 1.01199608762933 bayes_pls_golite062009
kinase activator activity 0.48120280834988 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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