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View Structure Prediction Details

Protein: AGX1
Organism: Saccharomyces cerevisiae
Length: 385 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGX1.

Description E-value Query
Range
Subject
Range
NFS1_ASHGO - Cysteine desulfurase, mitochondrial OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 /...
NFS1_ASHGO - Cysteine desulfurase, mitochondrial OS=Ashbya gossypii GN=NFS1 PE=3 SV=1
2.0E-88 [3..384] [90..469]
NFS1 - Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transc...
NFS1_YEAST - Cysteine desulfurase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NFS1...
gi|151943808 - gi|151943808|gb|EDN62108.1| nifs-like protein [Saccharomyces cerevisiae YJM789]
2.0E-88 [3..384] [97..476]
ISCS_SALPB - Cysteine desulfurase IscS OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=iscS PE=3 SV=1
ISCS_SALEP - Cysteine desulfurase IscS OS=Salmonella enteritidis PT4 (strain P125109) GN=iscS PE=3 SV=1
ISCS_SALG2 - Cysteine desulfurase IscS OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=iscS PE=3 SV=1
gi|204929449, gi... - gi|204929449|ref|ZP_03220523.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serov...
gi|200389006, gi... - gi|200389006|ref|ZP_03215618.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serov...
ISCS_SALTY - Cysteine desulfurase OS=Salmonella typhimurium GN=iscS PE=3 SV=1
ISCS_SALCH - Cysteine desulfurase OS=Salmonella choleraesuis GN=iscS PE=3 SV=1
gi|238912664 - gi|238912664|ref|ZP_04656501.1| cysteine desulfurase [Salmonella enterica subsp. enterica serovar Te...
ISCS_SALTY - Cysteine desulfurase OS=Salmonella typhimurium GN=iscS PE=3 SV=1
ISCS_SALPA - Cysteine desulfurase IscS OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=iscS PE=3 SV=1
lcl|NC_016856.1_... - [gene=nifS] [protein=cysteine desulfurase] [protein_id=YP_005238645.1] [location=complement(2733089....
ISCS_SALPA - Cysteine desulfurase OS=Salmonella paratyphi A GN=iscS PE=3 SV=1
ISCS_SALCH - Cysteine desulfurase OS=Salmonella choleraesuis GN=iscS PE=3 SV=1
ISCS_SALCH - Cysteine desulfurase IscS OS=Salmonella choleraesuis (strain SC-B67) GN=iscS PE=3 SV=1
gi|194471395, gi... - gi|194471395|ref|ZP_03077379.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serov...
ISCS_SALHS - Cysteine desulfurase IscS OS=Salmonella heidelberg (strain SL476) GN=iscS PE=3 SV=1
ISCS_SALNS - Cysteine desulfurase IscS OS=Salmonella newport (strain SL254) GN=iscS PE=3 SV=1
ISCS_SALTY - Cysteine desulfurase IscS OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=iscS PE...
gi|168821477, gi... - gi|205341918|gb|EDZ28682.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar W...
ISCS_SALDC - Cysteine desulfurase IscS OS=Salmonella dublin (strain CT_02021853) GN=iscS PE=3 SV=1
ISCS_SALPK - Cysteine desulfurase IscS OS=Salmonella paratyphi A (strain AKU_12601) GN=iscS PE=3 SV=1
gi|197263596, gi... - gi|197263596|ref|ZP_03163670.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serov...
ISCS_SALPB - Cysteine desulfurase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=iscS PE=3 SV=1
ISCS_SALA4 - Cysteine desulfurase IscS OS=Salmonella agona (strain SL483) GN=iscS PE=3 SV=1
gi|167992668, gi... - gi|205329088|gb|EDZ15852.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar 4...
gi|205325222, gi... - gi|205325222|gb|EDZ13061.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar S...
gi|168466701, gi... - gi|195630769|gb|EDX49361.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar N...
gi|168261415, gi... - gi|205349590|gb|EDZ36221.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar H...
gi|168243327, gi... - gi|205337629|gb|EDZ24393.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar H...
gi|205333600, gi... - gi|205333600|gb|EDZ20364.1| cysteine desulfurase IscS [Salmonella enterica subsp. enterica serovar K...
2.0E-88 [5..384] [4..383]
gi|213580753 - gi|213580753|ref|ZP_03362579.1| cysteine desulfurase [Salmonella enterica subsp. enterica serovar Ty...
ISCS_SALTI - Cysteine desulfurase IscS OS=Salmonella typhi GN=iscS PE=3 SV=1
gi|29136471, gi|... - gi|29140846|ref|NP_804188.1| cysteine desulfurase [Salmonella enterica subsp. enterica serovar Typhi...
gi|214000603 - gi|214000603|ref|ZP_03411338.1| cysteine desulfurase [Salmonella enterica subsp. enterica serovar Ty...
gi|213646425 - gi|213646425|ref|ZP_03376478.1| cysteine desulfurase [Salmonella enterica subsp. enterica serovar Ty...
ISCS_SALTI - Cysteine desulfurase OS=Salmonella typhi GN=iscS PE=3 SV=1
gi|16761457 - gi|16761457|ref|NP_457074.1| cysteine desulfurase [Salmonella enterica subsp. enterica serovar Typhi...
3.0E-88 [5..384] [4..383]
gi|12516934, gi|... - gi|15803057|ref|NP_289087.1| cysteine desulfurase [Escherichia coli O157:H7 EDL933], gi|12516934|gb|...
gi|13362867 - gi|13362867|dbj|BAB36819.1| cysteine desulfurase [Escherichia coli O157:H7 str. Sakai]
gi|73856533, gi|... - gi|74313056|ref|YP_311475.1| putative aminotransferase [Shigella sonnei Ss046], gi|73856533|gb|AAZ89...
gi|91211857, gi|... - gi|91211857|ref|YP_541843.1| cysteine desulfurase [Escherichia coli UTI89], gi|91073431|gb|ABE08312....
gi|115513882, gi... - gi|117624758|ref|YP_853671.1| cysteine desulfurase [Escherichia coli APEC O1], gi|115513882|gb|ABJ01...
gi|237705041, gi... - gi|237705041|ref|ZP_04535522.1| cysteine desulfurase [Escherichia sp. 3_2_53FAA], gi|226901407|gb|EE...
gi|7447233, gi|2... - gi|7447233|pir||A65030 probable iron-sulfur cofactor synthesis protein b2530 - Escherichia coli (str...
gi|26248898, gi|... - gi|26248898|ref|NP_754938.1| cysteine desulfurase [Escherichia coli CFT073], gi|26109304|gb|AAN81506...
gi|82777913, gi|... - gi|82777913|ref|YP_404262.1| putative aminotransferase [Shigella dysenteriae Sd197], gi|81242061|gb|...
gi|13362867 - gi|13362867|dbj|BAB36819.1| cysteine desulfurase [Escherichia coli O157:H7]
gi|82544979, gi|... - gi|82544979|ref|YP_408926.1| putative aminotransferase [Shigella boydii Sb227], gi|81246390|gb|ABB67...
3.0E-88 [5..384] [12..391]
ISCS_PASMU - Cysteine desulfurase OS=Pasteurella multocida GN=iscS PE=3 SV=1
ISCS_PASMU - Cysteine desulfurase IscS OS=Pasteurella multocida (strain Pm70) GN=iscS PE=3 SV=1
3.0E-87 [5..384] [4..383]
gi|229505638, gi... - gi|229505638|ref|ZP_04395148.1| cysteine desulfurase [Vibrio cholerae BX 330286], gi|229357861|gb|EE...
gi|229350006, gi... - gi|229513113|ref|ZP_04402579.1| cysteine desulfurase [Vibrio cholerae TMA 21], gi|229350006|gb|EEO14...
gi|229344527, gi... - gi|229517812|ref|ZP_04407256.1| cysteine desulfurase [Vibrio cholerae RC9], gi|229344527|gb|EEO09501...
gi|229608656, gi... - gi|229608656|ref|YP_002879304.1| cysteine desulfurase [Vibrio cholerae MJ-1236], gi|229371311|gb|ACQ...
gi|197752903, gi... - gi|254285466|ref|ZP_04960430.1| aminotransferase NifS, class V [Vibrio cholerae AM-19226], gi|197752...
gi|153824633, gi... - gi|153824633|ref|ZP_01977300.1| aminotransferase NifS, class V [Vibrio cholerae MZO-2], gi|149741851...
gi|126512180, gi... - gi|153817264|ref|ZP_01969931.1| aminotransferase NifS, class V [Vibrio cholerae NCTC 8457], gi|12651...
gi|126519747, gi... - gi|229510690|ref|ZP_04400169.1| cysteine desulfurase [Vibrio cholerae B33], gi|229350655|gb|EEO15596...
gi|75832008, gi|... - gi|75832008|ref|ZP_00761267.1| COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and rela...
ISCS_VIBC3 - Cysteine desulfurase IscS OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / ...
gi|75814869, gi|... - gi|75814869|ref|ZP_00745412.1| COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and rela...
ISCS_VIBCH - Cysteine desulfurase OS=Vibrio cholerae GN=iscS PE=3 SV=1
ISCS_VIBCH - Cysteine desulfurase IscS OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) G...
7.0E-87 [5..382] [4..381]
NIFS_TRIAZ - Cysteine desulfurase OS=Trichormus azollae GN=nifS PE=3 SV=1
NIFS1_ANAVT - Cysteine desulfurase 1 OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=nifS1 PE=3 SV=2
1.0E-86 [3..384] [1..379]
gi|25312963 - pir||AE1988 nitrogenase cofactor synthesis protein [imported] - Nostoc sp. (strain PCC 7120)
NIFS_NOSS1 - Cysteine desulfurase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=nifS PE=3 SV=3
1.0E-86 [3..384] [1..379]

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Predicted Domain #1
Region A:
Residues: [1-10]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKSVDTLLI 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [281-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRWDLHREMS DWFKDSLVNG LQLTSVSRYP SNMSAHGLTA VYVADPPDVI AFLKSHGVVI  60
   61 AGGIHKDIGP KYIRIGHMGV TACNKNLPYM KNCFDLIKLA LQRKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.09691
Match: 1ecxA_
Description: NifS-like protein/selenocysteine lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alanine-glyoxylate transaminase activity 5.09067995370888 bayes_pls_golite062009
serine-pyruvate transaminase activity 3.41330924856745 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 3.04830539911875 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 3.04830539911875 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 2.30133284041702 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 2.1692959843619 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.19150094103499 bayes_pls_golite062009
4-aminobutyrate transaminase activity 1.1251558546682 bayes_pls_golite062009
transferase activity 0.737426388870721 bayes_pls_golite062009
binding 0.513318446274735 bayes_pls_golite062009
L-allo-threonine aldolase activity 0.500744432308415 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
methyltransferase activity 0.093175965161657 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.0150995688991599 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [11-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGPIILSGAV QKALDVPSLG HTSPEFVSIF QRVLKNTRAV FKSAAASKSQ PFVLAGSGTL  60
   61 GWDIFASNFI LSKAPNKNVL VVSTGTFSDR FADCLRSYGA QVDVVRPLKI GESVPLELIT 120
  121 EKLSQNSYGA VTVTHVDTST AVLSDLKAIS QAIKQTSPET FFVVDAVCSI GCEEFEFDEW 180
  181 GVDFALTASQ KAIGAPAGLS ISLCSSRFMD YALNDSKNGH VHGYFSSLRR WTPIMENYEA 240
  241 GKGAYFATPP VQLINSLDVA LKEILEEGLH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.09691
Match: 1ecxA_
Description: NifS-like protein/selenocysteine lyase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle