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View Structure Prediction Details

Protein: GRX4
Organism: Saccharomyces cerevisiae
Length: 244 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRX4.

Description E-value Query
Range		 Subject
Range
GLRX4_YEAST - Monothiol glutaredoxin-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRX4 PE=1 SV=1
GRX4 - Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glut...
 7.0E-54 [1..244] [1..244]
GRS17_ARATH - Monothiol glutaredoxin-S17 OS=Arabidopsis thaliana GN=GRXS17 PE=1 SV=1
 9.0E-50 [2..239] [4..246]
GLRX3_MOUSE - Glutaredoxin-3 OS=Mus musculus GN=Glrx3 PE=1 SV=1
 2.0E-48 [1..238] [13..227]
grx4 - glutaredoxin Grx4
GLRX4_SCHPO - Monothiol glutaredoxin-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=grx4 PE=1 SV=1
 2.0E-48 [1..240] [1..240]
gi|123993795, gi... - gi|123995343|gb|ABM85273.1| protein disulfide isomerase family A, member 4 [synthetic construct], gi...
PDIA4 - protein disulfide isomerase family A, member 4
 1.0E-47 [4..243] [64..291]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-47 [4..236] [26..251]
gi|14626709, gi|... - gi|68394965|ref|XP_702014.1| PREDICTED: hypothetical protein XP_696922 [Danio rerio], gi|56207705|em...
 2.0E-47 [4..228] [27..262]

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Predicted Domain #1
Region A:
Residues: [1-137] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVVEIKSQD QFTQLTTTNA ANKLIVLYFK AQWADPCKTM SQVLEAVSEK VRQEDVRFLS  60
   61 IDADEHPEIS DLFEIAAVPY FVFIQNGTIV KEISAADPKE FVKSLEILSN ASASLANNAK 120
  121 GPKSTSDEES SGSSDDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.29073
Match: 1quwA_
Description: Thioredoxin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [138-244] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDETEEEINA RLVKLVQAAP VMLFMKGSPS EPKCGFSRQL VGILREHQIR FGFFDILRDE  60
   61 NVRQSLKKFS DWPTFPQLYI NGEFQGGLDI IKESIEEDPE YFQHALQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1b4qA_
Description: Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle