YRC Public Data Repository - Protein Structure Prediction

Protein:	PEA2
Organism:	Saccharomyces cerevisiae
Length:	420 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEA2.

Description	E-value	Query Range	Subject Range
PEA2 - Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity C... gi\|151944867 - gi\|151944867\|gb\|EDN63126.1\| coiled-coil polarisome protein [Saccharomyces cerevisiae YJM789] gi\|190405708 - gi\|190405708\|gb\|EDV08975.1\| coiled-coil domain [Saccharomyces cerevisiae RM11-1a] PEA2_YEAST - Protein PEA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEA2 PE=1 SV=1	0.0	[1..420]	[1..420]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-75	[172..395]	[12..245]
KLC1_RAT - Kinesin light chain 1 - Rattus norvegicus (Rat)	6.0E-75	[172..395]	[8..241]
gi\|14250822, gi\|... - gi\|33620730\|ref\|NP_005543.2\| kinesin light chain 1 isoform 1 [Homo sapiens], gi\|14250822\|gb\|AAH08881... gi\|124000151, gi... - gi\|124000151\|gb\|ABM87584.1\| kinesin 2 [synthetic construct], gi\|123993161\|gb\|ABM84182.1\| kinesin 2 [...	6.0E-75	[172..395]	[12..245]
KLC1_MOUSE - Kinesin light chain 1 OS=Mus musculus GN=Klc1 PE=1 SV=3	6.0E-73	[172..395]	[12..243]
KLC_DORPE - Kinesin light chain OS=Doryteuthis pealeii PE=2 SV=1 KLC_LOLPE - Kinesin light chain OS=Loligo pealeii PE=2 SV=1	2.0E-72	[165..395]	[4..252]

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Predicted Domain #1

Region A:
Residues: [1-137]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKFDLELSR RANPLLFSAE RYEEYPLKYD ELKQYLLSQN PSHPHHNSRP YTSIDYFDYL  60
   61 LYRSKNDESE IDLDKKLVSE FALYYVQKEH LNSDDLNPTL NELLKLQPKS ADWYEMMLRI 120
  121 LESINTTGID QLTKENN

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.29
Match:	1e6vA
Description:	Alpha chain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [138-420]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSFPNSKRAR SSTNMGGTDK FNKGAYHTDK ADDDKNEILQ ELTSFLMSNS IQKGIDIKPI  60
   61 PLDDPVKFLK NGINSILDTC VSLEKNTSSP PISPNAAAIQ EEDSSKKLEE LETAFSDLQL 120
  121 AHNFLTKQFE NDRAEYVQDI EKLTRTNREL QDKLLNNHSN LSKTEKKLHE LEQENKELEK 180
  181 ANNKLNSSRH NFGMSSPASS PVTWDPSSPS SVGSPTSGSG SRSLSIMTSE FKKVLTSTQR 240
  241 KYEKELSDER EHRFKLEREL ALLKNAEANT SLALNRDDPP DML

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.29
Match:	1e6vA
Description:	Alpha chain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits