YRC Public Data Repository - Protein Structure Prediction

Protein:	FTR1
Organism:	Saccharomyces cerevisiae
Length:	404 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTR1.

Description	E-value	Query Range	Subject Range
FTR1_YEAST - Plasma membrane iron permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FTR1 PE=1 ... gi\|190405704 - gi\|190405704\|gb\|EDV08971.1\| iron permease [Saccharomyces cerevisiae RM11-1a] FTR1 - High affinity iron permease involved in the transport of iron across the plasma membrane; forms comp...	0.0	[1..404]	[1..404]
gi\|7770291 - gi\|7770291\|gb\|AAF69680.1\| high-affinity iron permease CaFTR1 [Candida albicans]	0.0	[3..376]	[2..373]
FIP1_SCHPO - Plasma membrane iron permease OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fip1 PE=1 SV... fip1 - iron permease Fip1	3.0E-98	[1..318]	[1..317]
gi\|85075867 - gi\|85075867\|ref\|XP_955834.1\| hypothetical protein NCU03497 [Neurospora crassa OR74A] gi\|18376330, gi\|... - gi\|32404284\|ref\|XP_322755.1\| hypothetical protein [Neurospora crassa], gi\|28916855\|gb\|EAA26598.1\| hy...	2.0E-87	[4..331]	[2..403]
gi\|16799461 - gi\|16799461\|ref\|NP_469729.1\| hypothetical protein lin0384 [Listeria innocua Clip11262] gi\|25309255, gi\|... - pir\|\|AI1480 conserved hypothetical protein homolog lin0384 [imported] - Listeria innocua (strain Cli...	4.0E-52	[9..237]	[229..433]
gi\|13360723, gi\|... - gi\|15830517\|ref\|NP_309290.1\| putative cytochrome [Escherichia coli O157:H7 str. Sakai], gi\|13360723\|... gi\|253773953, gi... - gi\|253773953\|ref\|YP_003036784.1\| FTR1 family protein [Escherichia coli BL21(DE3)], gi\|253324997\|gb\|A... gi\|242376828, gi... - gi\|251784555\|ref\|YP_002998859.1\| hypothetical protein B21_01026 [Escherichia coli BL21], gi\|24237682... gi\|189358185, gi... - gi\|189358185\|gb\|EDU76604.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4401]... gi\|188018213, gi... - gi\|188018213\|gb\|EDU56335.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4113]... gi\|254792275, gi... - gi\|254792275\|ref\|YP_003077112.1\| ferrous iron permease [Escherichia coli O157:H7 str. TW14359], gi\|2... gi\|157160541, gi... - gi\|157160541\|ref\|YP_001457859.1\| iron permease FTR1 family protein [Escherichia coli HS], gi\|1570662... gi\|157156355, gi... - gi\|157156355\|ref\|YP_001462251.1\| FTR1 family iron permease [Escherichia coli E24377A], gi\|157078385\|... gi\|189001223, gi... - gi\|189001223\|gb\|EDU70209.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4076]... gi\|187770528, gi... - gi\|187770528\|gb\|EDU34372.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4196]... gi\|189363226, gi... - gi\|189363226\|gb\|EDU81645.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4486]... gi\|189368764, gi... - gi\|189368764\|gb\|EDU87180.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4501]... gi\|208737587, gi... - gi\|208822102\|ref\|ZP_03262421.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4... gi\|208815062, gi... - gi\|208815062\|ref\|ZP_03256241.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4... gi\|208806187, gi... - gi\|208806187\|ref\|ZP_03248524.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4... gi\|195935275 - gi\|195935275\|ref\|ZP_03080657.1\| FTR1 family protein [Escherichia coli O157:H7 str. EC4024] gi\|217318813, gi... - gi\|217328386\|ref\|ZP_03444468.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. TW1... gi\|209911531, gi... - gi\|209918272\|ref\|YP_002292356.1\| putative cytochrome [Escherichia coli SE11], gi\|209911531\|dbj\|BAG76... gi\|209398317, gi... - gi\|209398317\|ref\|YP_002269743.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC... gi\|190903004, gi... - gi\|191166892\|ref\|ZP_03028716.1\| iron permease FTR1 family protein [Escherichia coli B7A], gi\|1909030... gi\|188490646, gi... - gi\|188495447\|ref\|ZP_03002717.1\| iron permease FTR1 family protein [Escherichia coli 53638], gi\|18849... gi\|124500101, gi... - gi\|124529146\|ref\|ZP_01700256.1\| FTR1 family protein [Escherichia coli B], gi\|124500101\|gb\|EAY47579.1... gi\|169755511, gi... - gi\|170020583\|ref\|YP_001725537.1\| FTR1 family protein [Escherichia coli ATCC 8739], gi\|169755511\|gb\|A... gi\|189372680, gi... - gi\|189372680\|gb\|EDU91096.1\| iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC869],... gi\|194438030, gi... - gi\|194438030\|ref\|ZP_03070123.1\| iron permease FTR1 family protein [Escherichia coli 101-1], gi\|19442... EFEU_SHISS - Ferrous iron permease EfeU OS=Shigella sonnei (strain Ss046) GN=efeU PE=3 SV=2 gi\|194413547, gi... - gi\|194428495\|ref\|ZP_03061035.1\| iron permease FTR1 family protein [Escherichia coli B171], gi\|194413... gi\|192955913, gi... - gi\|193070802\|ref\|ZP_03051736.1\| iron permease FTR1 family protein [Escherichia coli E110019], gi\|192... gi\|192927854, gi... - gi\|193064602\|ref\|ZP_03045682.1\| iron permease FTR1 family protein [Escherichia coli E22], gi\|1929278... gi\|25390170 - pir\|\|G90786 probable cytochrome [imported] - Escherichia coli (strain O157:H7, substrain RIMD 050995... EFEU_ECO57 - Ferrous iron permease EfeU OS=Escherichia coli O157:H7 GN=efeU PE=1 SV=3	4.0E-48	[11..240]	[5..218]
gi\|218351284, gi... - gi\|218694552\|ref\|YP_002402219.1\| ferrous iron permease [Escherichia coli 55989], gi\|218351284\|emb\|CA... gi\|209773906, gi... - pir\|\|G85646 hypothetical protein Z1519 [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|15801008, gi\|... - gi\|15801008\|ref\|NP_287024.1\| hypothetical protein Z1519 [Escherichia coli O157:H7 EDL933], gi\|125143... gi\|73855057, gi\|... - gi\|74311580\|ref\|YP_309999.1\| high-affinity iron permease [Shigella sonnei Ss046], gi\|73855057\|gb\|AAZ... gi\|75195203 - gi\|75195203\|ref\|ZP_00705273.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli HS] gi\|75210295 - gi\|75210295\|ref\|ZP_00710457.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli B171] gi\|253977244, gi... - gi\|254287937\|ref\|YP_003053685.1\| hypothetical protein ECD_01019 [Escherichia coli BL21(DE3)], gi\|253... gi\|83586440 - gi\|83586440\|ref\|ZP_00925074.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli 101-1] gi\|254161129, gi... - gi\|254161129\|ref\|YP_003044237.1\| hypothetical protein ECB_01019 [Escherichia coli B str. REL606], gi... gi\|75190080 - gi\|75190080\|ref\|ZP_00703347.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli E24377A] gi\|75257459 - gi\|75257459\|ref\|ZP_00728962.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli E22] gi\|75513466 - gi\|75513466\|ref\|ZP_00735870.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli 53638] gi\|75229937 - gi\|75229937\|ref\|ZP_00716454.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli B7A] gi\|75234351 - gi\|75234351\|ref\|ZP_00718721.1\| COG0672: High-affinity Fe2+/Pb2+ permease [Escherichia coli E110019]	4.0E-48	[11..240]	[8..221]

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Predicted Domain #1

Region A:
Residues: [1-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNKVFNVAV FFVVFRECLE AVIVISVLLS FLKQAIGEHD RALYRKLRIQ VWVGVLLGFI  60
   61 ICLAIGAGFI GAYYSLQKDI FGSAEDLWEG IFCMIATIMI SMMGIPMLRM NKMQSKWRVK 120
  121 IARSLVEIPH RKRDYFKIGF LSRRYAMFLL PFITVLREGL EAVVFVAGAG ITTQGSHASA 180
  181 YPLPVVVGLI CGGLVGYLLY YGASKSSLQI FLILSTSILY LISAGLFSRG AWYFENYRFN 240
  241 LASGGDASEG GDGNGSYNIR KAVYHVNCCN PELDNGWDIF NALLGWQNTG YLSSMLCYNI 300
  301 YWLVLIIVLS LMIFEERRGH LPF

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	143.886057
Match:	PF03239
Description:	Iron permease FTR1 family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [324-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKNLQLKHLN PGYWIKNKKK QELTEEQKRQ LFAKMENINF NEDGEINVQE NYELPEQTTS  60
   61 HSSSQNVATD KEVLHVKADS L

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.347	a.77.1	DEATH domain
View	Download	0.666	d.68.3	SirA-like
View	Download	0.421	a.46.2	Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View	Download	0.365	a.165.1	Myosin phosphatase inhibitor 17kDa protein, CPI-17
View	Download	0.349	g.53.1	TAZ domain
View	Download	0.327	d.58.36	Sulfite reductase, domains 1 and 3
View	Download	0.301	a.4.1	Homeodomain-like
View	Download	0.289	a.4.11	RNA polymerase subunit RPB10
View	Download	0.273	a.135.1	Tetraspanin
View	Download	0.264	a.4.1	Homeodomain-like
View	Download	0.257	a.6.1	Putative DNA-binding domain
View	Download	0.255	a.24.7	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View	Download	0.251	a.16.1	S15/NS1 RNA-binding domain
View	Download	0.243	a.1.1	Globin-like
View	Download	0.243	a.4.12	TrpR-like
View	Download	0.242	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.238	a.144.1	PABC (PABP) domain
View	Download	0.234	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.229	d.58.17	Metal-binding domain
View	Download	0.215	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.210	a.60.7	5' to 3' exonuclease, C-terminal subdomain
View	Download	0.205	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.201	a.70.1	N-terminal domain of the delta subunit of the F1F0-ATP synthase

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits