YRC Public Data Repository - Protein Structure Prediction

Protein:	YER140W
Organism:	Saccharomyces cerevisiae
Length:	556 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YER140W.

Description	E-value	Query Range	Subject Range
YER140W - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi... gi\|190405699 - gi\|190405699\|gb\|EDV08966.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] TAPT1_YEAST - Endoplasmic reticulum membrane protein 65 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...	0.0	[1..556]	[1..556]
gi\|17381092 - gi\|17381092\|gb\|AAL36358.1\| unknown protein [Arabidopsis thaliana]	0.0	[28..460]	[190..614]
CE19819 - status:Confirmed UniProt:Q9U3H8 protein_id:CAB62802.1	0.0	[37..461]	[144..530]
TAPT1_SCHPO - Endoplasmic reticulum membrane protein 65 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=... SPBC13G1.05 - DUF747 family protein	0.0	[7..410]	[63..496]
gi\|125545511 - gi\|125545511\|gb\|EAY91650.1\| hypothetical protein OsI_012883 [Oryza sativa (indica cultivar-group)] gi\|125587706, gi... - gi\|50918313\|ref\|XP_469553.1\| hypothetical protein [Oryza sativa (japonica cultivar-group)], gi\|18071...	2.0E-74	[193..449]	[257..494]
gi\|23957778, gi\|... - gi\|8052286\|emb\|CAB39065.2\| hypothetical protein [Plasmodium falciparum 3D7], gi\|23957778\|ref\|NP_4733...	1.0E-41	[227..378]	[1038..1184]
gi\|6760350 - gi\|6760350\|gb\|AAF28308.1\| cytomegalovirus partial fusion receptor [Homo sapiens]	2.0E-15	[140..193]	[65..118]

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Predicted Domain #1

Region A:
Residues: [1-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHKDTAVAK DTAKKRLLRR NSAPSAIHII SRLDKKWSFL WNTIDRHNIV EEQDESSAAK  60
   61 SEEEHEDDYE LEQLLNMIRI PMFLEKFMLF ALLTSLDCFL YYFTVLPIRL IKGYVKQFKS 120
  121 YRQHYRLQQR SGHKNKIPF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.224	0.839	mitochondrion	c.2.1	NAD(P)-binding Rossmann-fold domains

Predicted Domain #2

Region A:
Residues: [140-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYRITSREYK ERCMIFIIVI SSILLSKLDT SKLYHRIKRQ STMKLYMLFS VLEMADKMLA  60
   61 SLGQSLLTVM LSRK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.816	0.000	mitochondrion	f.17.1	F1F0 ATP synthase subunit C

Predicted Domain #3

Region A:
Residues: [214-415]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSERILLHKC LLVSMSLTYV TIHGYVLVYQ AISLNIAVNS YSNALLTLLL SMQFAEIKSS  60
   61 VLKKFDKEGF FQITIADVVE RFKLTLLLSI TGLRNLQSWS SSLSNTSINF WSPRSTLSIV 120
  121 INILCGPMVS VVGSEVLVDW AKHAYITKFN RIRPQIYDKF YYIIYKDYST RTHKLEDRLG 180
  181 LPLPAFVVLF IVMVRPTLFK SS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [416-556]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPSYLPSLFR ILFMGASVFL LALLAKFTLD LILIKWSKRI EQRFRDQAFN TVVTEEEYVP  60
   61 GLLSGGMGKV DVSTRIALHS DYNKENRIET ESVSPMRKRK TTLTAECTPP SLNDIRRQKD 120
  121 SKNPRSLENV ARYKMVSKRI W

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits