YRC Public Data Repository - Protein Structure Prediction

Protein:	LCP5
Organism:	Saccharomyces cerevisiae
Length:	357 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LCP5.

Description	E-value	Query Range	Subject Range
LCP5 - Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processi... LCP5_YEAST - U3 small nucleolar ribonucleoprotein protein LCP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...	0.0	[1..357]	[1..357]
SAS10_MOUSE - Something about silencing protein 10 OS=Mus musculus GN=Utp3 PE=1 SV=1	3.0E-61	[4..251]	[212..447]
gi\|79317210, gi\|... - gi\|8439884\|gb\|AAF75070.1\|AC007583_6 F24B9.6 [Arabidopsis thaliana], gi\|79317210\|ref\|NP_001030989.1\| ...	9.0E-59	[5..314]	[11..269]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-58	[1..310]	[6..266]
SPAC18B11.06 - U3 snoRNP-associated protein Lcp5 YA36_SCHPO - Uncharacterized protein C18B11.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC18B1...	1.0E-57	[38..341]	[6..286]
gi\|123990964, gi... - gi\|157928510\|gb\|ABW03551.1\| disrupter of silencing 10 [synthetic construct], gi\|123990964\|gb\|ABM8392... UTP3 - UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	4.0E-57	[4..251]	[216..457]
gi\|13874614 - gi\|13874614\|dbj\|BAB46914.1\| hypothetical protein [Macaca fascicularis]	2.0E-56	[6..251]	[1..240]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELNALLKD INGSLTATSE SLERLSGIYS NSATDEIPES NQLHEHLFYD AKKPAEKVSL  60
   61 LSLKNGSMLG YINSLLMLIG NRLDDECKDP SAMDARERSI QHRVVLERGV KPLEKKLAYQ 120
  121 LDKLTRAYV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [130-357]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KMEKEYKDAE KRALEKSTLV NHSGNDDSED DESSEDEIAY RPNTSGIINT NKKSSAYRVE  60
   61 ETAKQENGEE NDDNETGVYK PPKITAVLPP QQTHFEDRFD AREHKDRSNK SRMQAMEEYI 120
  121 RESSDQPDWS ASIGADIVNH GRGGIKSLRD TEKERRVTSF EEDNFTRLNI TNKAEKRKQK 180
  181 QRERNARMNV IGGEDFGIFS SKRKLEDSTS RRGAKKTRSA WDRAQRRL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [255-357]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPDWSASIGA DIVNHGRGGI KSLRDTEKER RVTSFEEDNF TRLNITNKAE KRKQKQRERN  60
   61 ARMNVIGGED FGIFSSKRKL EDSTSRRGAK KTRSAWDRAQ RRL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits