YRC Public Data Repository - Protein Structure Prediction

Protein:	GLO3
Organism:	Saccharomyces cerevisiae
Length:	493 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLO3.

Description	E-value	Query Range	Subject Range
GLO3_YEAST - ADP-ribosylation factor GTPase-activating protein GLO3 OS=Saccharomyces cerevisiae (strain ATCC 2045... GLO3 - ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares ...	0.0	[1..493]	[1..493]
gi\|109451020, gi... - gi\|123999376\|gb\|ABM87252.1\| ADP-ribosylation factor GTPase activating protein 3 [synthetic construct... gi\|20070255, gi\|... - gi\|47678295\|emb\|CAG30268.1\| ARFGAP1 [Homo sapiens], gi\|20070255\|ref\|NP_055385.2\| ADP-ribosylation fa... HGNC:661\|MIM:612... - factor GTPase activating protein 3	0.0	[12..490]	[6..506]
gi\|30841021, gi\|... - gi\|30841021\|ref\|NP_079721.2\| ADP-ribosylation factor GTPase activating protein 3 [Mus musculus], gi\|...	0.0	[12..491]	[6..515]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-91	[50..490]	[1..463]

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Predicted Domain #1

Region A:
Residues: [1-163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNDEGETFA TEQTTQQVFQ KLGSNMENRV CFDCGNKNPT WTSVPFGVML CIQCSAVHRN  60
   61 MGVHITFVKS STLDKWTINN LRRFKLGGNH KARDFFLKNN GKQLLNTANV DAKTKYTSPV 120
  121 AKKYKIHLDK KVQKDMELYP SELVLNGQDS SDSPLDTDSD ASR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	149.154902
Match:	1dcqA_
Description:	Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [164-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSKENSVDD FFSNWQKPSS NSSSKLNVNT GSLAPKNNTT GSTPKTTVTK TRSSILTASR  60
   61 KKPVLNSQDK KKHSILSSSR KPTRL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [249-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAKKVDKSQA EDLFDQFKKE AQQEKEDEFT NSSSSTKIRQ NDYDSQFMNN SKGNNNNSID  60
   61 DINTQPDEFN DFLNDTSNSF DTTRKEQQDT LTPKFAKLGF GMTMNDANDL AKQQKESQKI 120
  121 AQGPRYTGRI AERYGTQKAI SSDQLFGRGS FDEAANREAH DKLKTFDNAT SISSSSYFGE 180
  181 D

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [430-493]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEVDEFGNPI NSSGSGAGNF DGRNSNNGFI DFNASADDEL QMLRDVVEQG AEKLGSYLRD  60
   61 YLRK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits