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View Structure Prediction Details

Protein: SCS2
Organism: Saccharomyces cerevisiae
Length: 244 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCS2.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 1.0E-54 [3..236] [6..244]
SCS2 - Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT...
gi|207345868 - gi|207345868|gb|EDZ72550.1| YER120Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190405682 - gi|190405682|gb|EDV08949.1| hypothetical protein SCRG_04596 [Saccharomyces cerevisiae RM11-1a]
SCS2_YEAST - Vesicle-associated membrane protein-associated protein SCS2 OS=Saccharomyces cerevisiae (strain ATCC...
 1.0E-51 [1..244] [1..244]
VAP11_ARATH - Vesicle-associated protein 1-1 OS=Arabidopsis thaliana GN=PVA11 PE=1 SV=1
 5.0E-49 [3..207] [22..221]
gi|8099350 - gi|8099350|gb|AAF72105.1|AF154847_1 33 kDa Vamp-associated protein [Homo sapiens]
 3.0E-47 [7..242] [12..236]
VAPB_RAT - Vesicle-associated membrane protein-associated protein B OS=Rattus norvegicus GN=Vapb PE=1 SV=3
 6.0E-47 [4..238] [8..234]
VP33_APLCA - Vesicle-associated membrane protein/synaptobrevin-binding protein OS=Aplysia californica PE=2 SV=1
 2.0E-46 [3..240] [8..252]

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Predicted Domain #1
Region A:
Residues: [1-162] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVEISPDV LVYKSPLTEQ STEYASISNN SDQTIAFKVK TTAPKFYCVR PNAAVVAPGE  60
   61 TIQVQVIFLG LTEEPAADFK CRDKFLVITL PSPYDLNGKA VADVWSDLEA EFKQQAISKK 120
  121 IKVKYLISPD VHPAQNQNIQ ENKETVEPVV QDSEPKEVPA VV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1grwA_
Description: Major sperm protein, MSP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [163-244] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEKEVPAEPE TQPPVQVKKE EVPPVVQKTV PHENEKQTSN STPAPQNQIK EAATVPAENE  60
   61 SSSMGIFILV ALLILVLGWF YR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle