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View Structure Prediction Details

Protein: UBP9
Organism: Saccharomyces cerevisiae
Length: 754 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP9.

Description E-value Query
Range
Subject
Range
UBP9 - Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fu...
UBP9_YEAST - Ubiquitin carboxyl-terminal hydrolase 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
0.0 [1..754] [1..754]
gi|5734755, gi|2... - gi|5734755|gb|AAD50020.1|AC007651_15 Unknown protein [Arabidopsis thaliana], pir||H86306 F20D23.20 p...
2.0E-86 [170..736] [230..779]
gi|3800764 - gi|3800764|gb|AAC68865.1| ubiquitin specific protease 66 [Gallus gallus]
1.0E-83 [336..665] [38..376]
gi|16552833, gi|... - gi|21361712|ref|NP_004196.3| ubiquitin specific peptidase 2 isoform a [Homo sapiens], gi|16552833|db...
7.0E-78 [236..665] [149..597]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-76 [41..691] [228..887]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKRWLSVNR KKSHPEKNTQ GNDEINRKAT SLKKTKGSGD PSIAKSPSAK SSTSSIPSNL  60
   61 ASHERRSKFS SQTD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.292 a.4.1 Homeodomain-like
View Download 0.207 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #2
Region A:
Residues: [75-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLAGNKHYHE HYHNMASTSD EREYDSSTTY EDRAFDTESS ILFTTITDLM PYGDGSNKVF  60
   61 GYENFGNTCY CNSVLQCLYN IPEFRCNVLR YPERVAAVNR IRKSDLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.823909
Match: PF00442
Description: No description for PF00442 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [182-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSKIRVFTNE SFETSTNSGN SNTGYQSNDN EDAHNHHHLQ QSDQDNSSSS TQEKQNNFER  60
   61 KRNSFMGFGK DKSNYKDSAK KDDNNEMERP QPVHTVVMAS DTLTE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.241 a.1.1 Globin-like
View Download 0.218 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.644 a.61.1 Retroviral matrix proteins
View Download 0.457 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.425 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.333 b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.324 a.60.2 RuvA domain 2-like
View Download 0.320 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.252 c.55.5 MTH1175-like

Predicted Domain #4
Region A:
Residues: [287-530]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLHEGCKKII VGRPLLKQSD SLSKASTTDC QANSHCQCDS QGSRITSVDD DVLVNPESCN  60
   61 DAVNNSNNNK ENTFPTSEQR KKAALIRGPV LNVDHLLYPT EEATLYNGLK DIFESITENL 120
  121 SLTGIVSPTE FVKILKKENV LFNTMMQQDA HEFLNFLLND FSEYIQRNNP RMRFGPQKTD 180
  181 NSNDNFITDL FKGTLTNRIK CLTCDNITSR DEPFLDFPIE VQGDEETDIQ KMLKSYHQRE 240
  241 MLNG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [531-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNKFYCNKCY GLQEAERMVG LKQLPHILSL HLKRFKYSEE QKSNIKLFNK ILYPLTLDVS  60
   61 STFNTS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.756 b.38.1 Sm-like ribonucleoproteins
View Download 0.747 b.34.5 Translation proteins SH3-like domain
View Download 0.698 d.18.1 ssDNA-binding transcriptional regulator domain
View Download 0.688 b.34.5 Translation proteins SH3-like domain
View Download 0.672 b.38.1 Sm-like ribonucleoproteins
View Download 0.634 d.9.2 Description not found.
View Download 0.633 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.633 b.38.1 Sm-like ribonucleoproteins
View Download 0.613 d.50.1 dsRNA-binding domain-like
View Download 0.599 b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.597 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.572 b.38.1 Sm-like ribonucleoproteins
View Download 0.566 d.95.1 Glucose permease domain IIB
View Download 0.553 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.543 d.50.1 dsRNA-binding domain-like
View Download 0.540 b.38.1 Sm-like ribonucleoproteins
View Download 0.540 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.529 d.95.1 Glucose permease domain IIB
View Download 0.505 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.459 b.38.1 Sm-like ribonucleoproteins
View Download 0.443 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.432 b.38.1 Sm-like ribonucleoproteins
View Download 0.429 b.38.1 Sm-like ribonucleoproteins
View Download 0.429 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.423 b.84.1 Single hybrid motif
View Download 0.402 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.390 b.93.1 Epsilon subunit of F1F0-ATP synthase N-terminal domain
View Download 0.389 b.40.2 Bacterial enterotoxins
View Download 0.378 b.93.1 Epsilon subunit of F1F0-ATP synthase N-terminal domain
View Download 0.376 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.369 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.363 g.27.1 Fibronectin type I module
View Download 0.350 b.40.4 Nucleic acid-binding proteins
View Download 0.340 g.51.1 Zn-binding domains of ADDBP
View Download 0.339 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.336 d.17.1 Cystatin/monellin
View Download 0.334 d.54.1 Enolase N-terminal domain-like
View Download 0.331 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.330 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.314 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.314 g.51.1 Zn-binding domains of ADDBP
View Download 0.312 d.17.1 Cystatin/monellin
View Download 0.304 d.17.1 Cystatin/monellin
View Download 0.298 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.297 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.292 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.285 b.1.5 Transglutaminase, two C-terminal domains
View Download 0.273 d.17.1 Cystatin/monellin
View Download 0.269 d.198.1 Type III secretory system chaperone
View Download 0.266 b.56.1 Transcription factor IIA (TFIIA), beta-barrel domain
View Download 0.266 b.71.1 Glycosyl hydrolase domain
View Download 0.263 b.56.1 Transcription factor IIA (TFIIA), beta-barrel domain
View Download 0.258 d.204.1 Ribosome binding protein Y (YfiA homologue)
View Download 0.247 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.243 b.55.1 PH domain-like
View Download 0.226 d.17.1 Cystatin/monellin
View Download 0.218 d.17.1 Cystatin/monellin
View Download 0.218 d.17.1 Cystatin/monellin
View Download 0.216 b.1.1 Immunoglobulin
View Download 0.213 d.17.1 Cystatin/monellin
View Download 0.207 b.71.1 Glycosyl hydrolase domain
View Download 0.201 b.40.4 Nucleic acid-binding proteins
View Download 0.201 b.40.4 Nucleic acid-binding proteins
View Download 0.201 b.40.4 Nucleic acid-binding proteins
View Download 0.200 d.17.1 Cystatin/monellin
View Download 0.200 d.17.1 Cystatin/monellin

Predicted Domain #6
Region A:
Residues: [597-687]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VYKKYELSGV VIHMGSGPQH GHYVCICRNE KFGWLLYDDE TVESIKEETV LQFTGHPGDQ  60
   61 TTAYVLFYKE TQADKTENQN ENIDTSSQDQ M

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 28.958607
Match: PF00443
Description: Ubiquitin carboxyl-terminal hydrolase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [688-754]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTDNNIEQLI KCDDWLRDRK LRAAANIERK KTLGNIPEVK TAETKTPLND KKRNKQKRKS  60
   61 RILSFIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.644 a.61.1 Retroviral matrix proteins
View Download 0.425 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.324 a.60.2 RuvA domain 2-like
View Download 0.457 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.320 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.306 a.64.1 Saposin
View Download 0.300 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.272 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.251 a.118.1 ARM repeat
View Download 0.250 d.50.3 PI-Pfui intein middle domain
View Download 0.224 g.34.1 HIV-1 VPU cytoplasmic domain
View Download 0.219 a.60.1 SAM/Pointed domain
View Download 0.205 a.7.7 BAG domain
View Download 0.202 a.4.1 Homeodomain-like
View Download 0.202 a.28.2 Colicin E immunity proteins


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle