| Protein: | TSC11 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1430 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TSC11.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1430] | [1..1430] |
|
|
0.0 | [108..1429] | [14..1306] |
|
|
0.0 | [288..1405] | [32..1134] |
|
|
0.0 | [288..1405] | [32..1134] |
|
|
0.0 | [411..1156] | [1..786] |
|
|
4.0E-69 | [2..416] | [878..1283] |
|
Region A: Residues: [1-52] |
1 11 21 31 41 51
| | | | | |
1 MSIPHSAKQS SPLSSRRRSV TNTTPLLTPR HSRDNSSTQI SSAKNITSSS PS
|
| Detection Method: |  |
| Confidence: | 44.09691 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [53-72] |
1 11 21 31 41 51
| | | | | |
1 TITNESSKRN KQNLVLSTSF
|
|
Region B: Residues: [152-180] |
1 11 21 31 41 51
| | | | | |
1 MRIRANTQLR EIDNSIKRVE KHIFDLKQQ
|
| Detection Method: | |
| Confidence: | 5.154902 |
| Match: | 1cii__ |
| Description: | Colicin Ia; Colicin Ia, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [73-151] |
1 11 21 31 41 51
| | | | | |
1 ISTKRLENSA PSPTSPLMAR RTRSTMTKAL LNLKAEINNQ YQELARLRKK KDDIEHLRDS 60
61 TISDIYSGSY STNHLQKHS
|
|
Region B: Residues: [181-211] |
1 11 21 31 41 51
| | | | | |
1 FDKKRQRSLT TSSSIKADVG SIRNDDGQNN D
|
| Detection Method: | |
| Confidence: | 5.154902 |
| Match: | 1cii__ |
| Description: | Colicin Ia; Colicin Ia, N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [212-467] |
1 11 21 31 41 51
| | | | | |
1 SEELGDHDSL TDQVTLDDEY LTTPTSGTER NSQQNLNRNS TVNSRNNENH STLSIPDLDG 60
61 SNKVNLTGDT EKDLGDLENE NQIFTSTTTE AATWLVSDYM QSFQEKNVNP DFIAQKANGL 120
121 VTLLKEHSEI RKDLVLTSFM SSIQNLLLNG NKLIAASAYR VCRYLINSSI FIDELLELRL 180
181 DAFIIISLAK DNSFQIEREQ ALKMVRRFIE YNNGVTQGIM QAIISCVEKP EDSLRHMALE 240
241 TLLELCFVAP EMVKEC
|
| Detection Method: | |
| Confidence: | 5.154902 |
| Match: | 1cii__ |
| Description: | Colicin Ia; Colicin Ia, N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [468-588] |
1 11 21 31 41 51
| | | | | |
1 RGMRVIEGFL QDYTSFSLAS VILDTILQLM ATHKTRQHFL EDFNVSVLTT VFSDTNTKSN 60
61 VNVEKMQNAS TLISITLNSY NGFMLFSNNN FKPLKQLVSF FQIPICAQYL IDIFLDVLKI 120
121 K
|
| Detection Method: | |
| Confidence: | 7.18 |
| Match: | 1bkdS |
| Description: | Son of sevenless protein homolog 1 (sos-1) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [589-906] |
1 11 21 31 41 51
| | | | | |
1 PLPYKPRGRH SHSFKPIPSQ YYKECMSVNQ RLALIVLILE NSEFVPHLLE LLNEEDRDDH 60
61 LVAKGRYLLT EYFNLRMNLV DKKYTSVSKP IYKENFTYVN ETFQFKKIAY KMNRNRNTIG 120
121 MSGIDYAQNI KSFSKNIKEN TLLREVDDFR FRRMVYDSKV LQTKDFTRWN WNIINELLEG 180
181 PLLNKKQLEE LVKSTKFIRR LLVFYRPLRL RFSNVNKGAK LSQKYVQVGC QFFKTLTATP 240
241 EGMKILMDDT KIIPQLASLM FRAMEGNISG NIFNKNKLRE KIIFGYFKFI GILTQSKNGV 300
301 HILTRWNFFT VIYKMFQF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [907-1282] |
1 11 21 31 41 51
| | | | | |
1 ESKLGLEFLL LTIPELDLKY SSHCRVIIGK ALVVANEKVR IEATKHIGDK LKELLSTKES 60
61 DLKLKANKVK LQQFKMEMLT RQLYDLSPSV VAVADQALYE CIVAGNGSEE LGTSFRMFLN 120
121 QMVFIRSPIL FELLSRPYGF QLLNEINFVK EERDSWLSKK NIEYVHIVEE FLKKNESINA 180
181 KSLTFQQKSR LPLHFYESLT KTEDGILLLS QTGDLVTFMN VIKKYVNGNN MATVENAKEI 240
241 LDLKAALWCV GFIGSTELGI GLLDNYSLVE DIIEVAYNAS VTSVRFTAFY VLGLISMTRE 300
301 GCEILDEMGW NCCVSVQDEP IGIALPNRLD RFLSYNEHKW SAFGEYSDEM IVFNKSDGDL 360
361 IEKCLPIEFD LDKLLK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1283-1430] |
1 11 21 31 41 51
| | | | | |
1 EKDTAENPLN EKIITNKYDN DITSQTITVS GENSSLFANE GLSSPYVTQY RNDDDSIESK 60
61 VLHIVSQLGN HILSNHAVKE ITEINNKYGP RLFENEKMFF KVFNMMSKYR FKPHVRKFLC 120
121 GLFINNRALE NVIRHDNKRD KRPANFTR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.242 | a.26.1 | 4-helical cytokines |
| View | Download | 0.427 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.233 | a.118.8 | TPR-like |
| View | Download | 0.286 | a.23.2 | Diol dehydratase, gamma subunit |
| View | Download | 0.212 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
|
Region A: Residues: [1225-1299] |
1 11 21 31 41 51
| | | | | |
1 EPIGIALPNR LDRFLSYNEH KWSAFGEYSD EMIVFNKSDG DLIEKCLPIE FDLDKLLKEK 60
61 DTAENPLNEK IITNK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1300-1430] |
1 11 21 31 41 51
| | | | | |
1 YDNDITSQTI TVSGENSSLF ANEGLSSPYV TQYRNDDDSI ESKVLHIVSQ LGNHILSNHA 60
61 VKEITEINNK YGPRLFENEK MFFKVFNMMS KYRFKPHVRK FLCGLFINNR ALENVIRHDN 120
121 KRDKRPANFT R
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.427 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.286 | a.23.2 | Diol dehydratase, gamma subunit |
| View | Download | 0.242 | a.26.1 | 4-helical cytokines |
| View | Download | 0.241 | a.26.1 | 4-helical cytokines |
| View | Download | 0.233 | a.118.8 | TPR-like |
