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View Structure Prediction Details

Protein: RNR1
Organism: Saccharomyces cerevisiae
Length: 888 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNR1.

Description E-value Query
Range
Subject
Range
RIR1_YEAST - Ribonucleoside-diphosphate reductase large chain 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...
RNR1 - One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex cataly...
0.0 [1..888] [1..888]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..888] [17..885]
gi|7271006 - gi|7271006|emb|CAB77640.1| ribonucleotide reductase large subunit [Candida albicans]
gi|68481493, gi|... - gi|68481493|ref|XP_715255.1| hypothetical protein CaO19.13201 [Candida albicans SC5314], gi|68481362...
0.0 [1..888] [1..854]
RIR1_ARATH - Ribonucleoside-diphosphate reductase large subunit OS=Arabidopsis thaliana GN=RNR1 PE=1 SV=1
0.0 [1..780] [1..795]
RRM1 - ribonucleotide reductase M1
gi|123991808, gi... - gi|123999422|gb|ABM87271.1| ribonucleotide reductase M1 polypeptide [synthetic construct], gi|123991...
0.0 [1..761] [1..757]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYVYKRDGRK EPVQFDKITA RISRLCYGLD PKHIDAVKVT QRIISGVYEG VTTIELDNLA  60
   61 AETCAYMTTV HPDYATLAAR IAISNLHKQT TKQFSKVVED LYRYVNAATG KPAPMISDDV 120
  121 YNIVMENKDK LNSAIVYDRD FQYSYFGFKT LERSYLLRIN GQVAERPQHL IMRVALGIHG 180
  181 RDIEAALETY 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [630-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRRVLSGEFQ V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1616.9897
Match: 2r1rA_
Description: R1 subunit of ribonucleotide reductase, N-terminal domain; R1 subunit of ribonucleotide reductase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [191-629]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLMSLKYFTH ASPTLFNAGT PKPQMSSCFL VAMKEDSIEG IYDTLKECAL ISKTAGGIGL  60
   61 HIHNIRSTGS YIAGTNGTSN GLIPMIRVFN NTARYVDQGG NKRPGAFALY LEPWHADIFD 120
  121 FIDIRKNHGK EEIRARDLFP ALWIPDLFMK RVEENGTWTL FSPTSAPGLS DCYGDEFEAL 180
  181 YTRYEKEGRG KTIKAQKLWY SILEAQTETG TPFVVYKDAC NRKSNQKNLG VIKSSNLCCE 240
  241 IVEYSAPDET AVCNLASVAL PAFIETSEDG KTSTYNFKKL HEIAKVVTRN LNRVIDRNYY 300
  301 PVEEARKSNM RHRPIALGVQ GLADTFMLLR LPFDSEEARL LNIQIFETIY HASMEASCEL 360
  361 AQKDGPYETF QGSPASQGIL QFDMWDQKPY GMWDWDTLRK DIMKHGVRNS LTMAPMPTAS 420
  421 TSQILGYNEC FEPVTSNMY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [641-803]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNPYLLRDLV DLGIWDEGMK QYLITQNGSI QGLPNVPQEL KDLYKTVWEI SQKTIINMAA  60
   61 DRSVYIDQSH SLNLFLRAPT MGKLTSMHFY GWKKGLKTGM YYLRTQAASA AIQFTIDQKI 120
  121 ADQATENVAD ISNLKRPSYM PSSASYAASD FVPAAVTANA TIP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1616.9897
Match: 2r1rA_
Description: R1 subunit of ribonucleotide reductase, N-terminal domain; R1 subunit of ribonucleotide reductase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [804-888]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLDSSSEASR EASPAPTGSH SLTKGMAELN VQESKVEVPE VPAPTKNEEK AAPIVDDEET  60
   61 EFDIYNSKVI ACAIDNPEAC EMCSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle