YRC Public Data Repository - Protein Structure Prediction

Protein:	PIC2
Organism:	Saccharomyces cerevisiae
Length:	300 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIC2.

Description	E-value	Query Range	Subject Range
gi\|16549529 - gi\|16549529\|dbj\|BAB70825.1\| unnamed protein product [Homo sapiens]	5.0E-80	[2..298]	[90..383]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-79	[2..296]	[183..472]
gi\|151942810 - gi\|151942810\|gb\|EDN61156.1\| amino acid transporter [Saccharomyces cerevisiae YJM789] AGC1 - Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutama... AGC1_YEAST - Mitochondrial aspartate-glutamate transporter AGC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...	5.0E-78	[21..297]	[533..817]
UCP3_PIG - Mitochondrial uncoupling protein 3 OS=Sus scrofa GN=UCP3 PE=2 SV=1	4.0E-76	[9..294]	[4..297]
gi\|18380992, gi\|... - gi\|18380992\|gb\|AAH22114.1\| Slc25a25 protein [Mus musculus], gi\|18043565\|gb\|AAH19978.1\| Slc25a25 prot...	1.0E-75	[2..298]	[72..365]
UCP3_RAT - Mitochondrial uncoupling protein 3 OS=Rattus norvegicus GN=Ucp3 PE=2 SV=1	2.0E-75	[9..294]	[4..297]
UCP3_BOVIN - Mitochondrial uncoupling protein 3 OS=Bos taurus GN=UCP3 PE=2 SV=1	4.0E-75	[15..294]	[10..300]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESNKQPRKI QLYTKEFYAT CTLGGIIACG PTHSSITPLD LVKCRLQVNP KLYTSNLQGF  60
   61 RKIIANEGWK KVYTGFGATF VGYSLQGAGK YGGYEYFKHL YSSWLSPGVT VYLMASATAE 120
  121 FLADIMLCPF EAIKVKQQTT MPPFCNNVVD GWKKMYAESG GMKAFYKGIV PLWCRQIPYT 180
  181 MCKFTSFEKI VQKIYSVLPK KKEEMNALQQ ISVSFVGGYL AGILCAAVSH PADVMVSKIN 240
  241 SERKANESMS VASKRIYQKI GFTGLWNGLM VRIVMIGTLT SFQWLIYDSF KAYVGLPTTG 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.43
Match:	1is2A
Description:	Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits