YRC Public Data Repository - Protein Structure Prediction

Protein:	PHM8
Organism:	Saccharomyces cerevisiae
Length:	321 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHM8.

Description	E-value	Query Range	Subject Range
gi\|151944747 - gi\|151944747\|gb\|EDN63006.1\| phosphate metabolism-related protein [Saccharomyces cerevisiae YJM789] gi\|190405598 - gi\|190405598\|gb\|EDV08865.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207345985 - gi\|207345985\|gb\|EDZ72619.1\| YER037Wp-like protein [Saccharomyces cerevisiae AWRI1631] PHM8_YEAST - Phosphate metabolism protein 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHM8 PE=1... PHM8 - Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Ph...	3.0E-56	[1..321]	[1..321]
Y1777_PYRFU, YH7... - (Q8U040) Putative HAD-hydrolase PF1777 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PF1777 OS=Pyrococ... G3PP_PYRFU - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 84...	2.0E-40	[50..292]	[2..240]
G3PP_PYRAB - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB05140 PE=3 ... YB10_PYRAB - Uncharacterized HAD-hydrolase PYRAB05140 OS=Pyrococcus abyssi GN=PYRAB05140 PE=3 SV=1	3.0E-40	[52..289]	[2..235]
YG55_PYRHO, Y165... - (O59346) Putative HAD-hydrolase PH1655 (EC 3.-.-.-), Uncharacterized HAD-hydrolase PH1655 OS=Pyrococ... G3PP_PYRHO - Glyceraldehyde 3-phosphate phosphatase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JC...	1.0E-38	[52..293]	[2..239]
gi\|75516147, gi\|... - gi\|75516147\|ref\|ZP_00738265.1\| COG0546: Predicted phosphatases [Escherichia coli 53638], gi\|18849334... gi\|157162861, gi... - gi\|75197316\|ref\|ZP_00707386.1\| COG0546: Predicted phosphatases [Escherichia coli HS], gi\|157162861\|r... gi\|226839055, gi... - gi\|254038549\|ref\|ZP_04872605.1\| phosphoglycolate phosphatase [Escherichia sp. 1_1_43], gi\|226839055\|... gi\|209756690, gi... - pir\|\|C91157 phosphoglycolate phosphatase [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|254795299, gi... - gi\|254795299\|ref\|YP_003080136.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. TW14359... gi\|209397865, gi... - gi\|209397865\|ref\|YP_002272819.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4115]... gi\|15803888, gi\|... - gi\|15803888\|ref\|NP_289924.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|208741353, gi... - gi\|208821230\|ref\|ZP_03261550.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4042],... gi\|217325172, gi... - gi\|217325172\|ref\|ZP_03441256.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. TW14588]... gi\|124500814, gi... - gi\|124528159\|ref\|ZP_01699492.1\| phosphoglycolate phosphatase [Escherichia coli B], gi\|124500814\|gb\|E... gi\|168779465, gi... - gi\|189002264\|gb\|EDU71250.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4076], gi\|... gi\|168772727, gi... - gi\|187771456\|gb\|EDU35300.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4196], gi\|... gi\|168797152, gi... - gi\|189380127\|gb\|EDU98543.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC508], gi\|1... gi\|168785186, gi... - gi\|189374428\|gb\|EDU92844.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC869], gi\|1... gi\|195934873 - gi\|195934873\|ref\|ZP_03080255.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4024] GPH_ECO57 - Phosphoglycolate phosphatase OS=Escherichia coli O157:H7 GN=gph PE=3 SV=1 gi\|15833481, gi\|... - gi\|15833481\|ref\|NP_312254.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|170018379, gi... - gi\|170018379\|ref\|YP_001723333.1\| phosphoglycolate phosphatase [Escherichia coli ATCC 8739], gi\|16975... gi\|208814054, gi... - gi\|208814054\|ref\|ZP_03255383.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4045],... gi\|208727293, gi... - gi\|208807492\|ref\|ZP_03249829.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4206],... gi\|189359166, gi... - gi\|189359166\|gb\|EDU77585.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4401], gi\|... gi\|168751804, gi... - gi\|188014205\|gb\|EDU52327.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4113], gi\|... gi\|189364353, gi... - gi\|189364353\|gb\|EDU82772.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4486], gi\|... gi\|168759406, gi... - gi\|189369601\|gb\|EDU88017.1\| phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4501], gi\|...	5.0E-37	[50..287]	[5..248]
gi\|30696124, gi\|... - gi\|30696124\|ref\|NP_564718.2\| haloacid dehalogenase-like hydrolase family protein [Arabidopsis thalia...	7.0E-37	[9..275]	[33..285]
GPH_SALTI - Phosphoglycolate phosphatase OS=Salmonella typhi GN=gph PE=3 SV=1 GPH_SALTI - Phosphoglycolate phosphatase OS=Salmonella typhi GN=gph PE=3 SV=1 gi\|16762805 - gi\|16762805\|ref\|NP_458422.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica serov...	1.0E-36	[49..288]	[4..249]
GPH_SALTY - Phosphoglycolate phosphatase OS=Salmonella typhimurium GN=gph PE=3 SV=1 GPH_SALTY - Phosphoglycolate phosphatase OS=Salmonella typhimurium GN=gph PE=3 SV=1 gi\|167994587, gi... - gi\|205327601\|gb\|EDZ14365.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica serova... lcl\|NC_016856.1_... - [gene=gph] [protein=phosphoglycolate phosphatase] [protein_id=YP_005239680.1] [location=complement(3... GPH_SALTY - Phosphoglycolate phosphatase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=gph ...	1.0E-36	[47..288]	[2..249]

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Predicted Domain #1

Region A:
Residues: [1-72]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIAKDYRTI YRNQIKKQIR LNQEHLQSLT HLGSQINFEV DPPKLPDPDP ARKVFFFDID  60
   61 NTLYRKSTKV QL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [130-321]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLPLQDYLKP DWKLRELLIN LKKKKLGKFD KLWLFTNSYK NHAIRCVKIL GIADLFDGIT  60
   61 YCHYDRPIEE EFICKPDPKF FETAKLQSGL SSFANAWFID DNESNVRSAL SMGMGHVIHL 120
  121 IEDYQYESEN IVTKDHKNKQ QFSILKDILE IPLIMDVEVY RPSSIAIKEM EELEEEGEAV 180
  181 NWSNQQINVQ SS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.39794
Match:	1fezA_
Description:	Phosphonoacetaldehyde hydrolase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [73-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMQQSLSNFF KYELGFDDDE AERLIESYYQ EYGLSVKGLI KNKQIDDVLQ YNTFIDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.39794
Match:	1fezA_
Description:	Phosphonoacetaldehyde hydrolase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits