YRC Public Data Repository - Protein Structure Prediction

Protein:	GCD11
Organism:	Saccharomyces cerevisiae
Length:	527 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCD11.

Description	E-value	Query Range	Subject Range
gi\|151944735 - gi\|151944735\|gb\|EDN62994.1\| translational initiation factor eIF-2 gamma subunit [Saccharomyces cerev... gi\|190405587 - gi\|190405587\|gb\|EDV08854.1\| translational initiation factor eIF-2 gamma subunit [Saccharomyces cerev... gi\|207346006 - gi\|207346006\|gb\|EDZ72633.1\| YER025Wp-like protein [Saccharomyces cerevisiae AWRI1631] IF2G_YEAST - Eukaryotic translation initiation factor 2 subunit gamma OS=Saccharomyces cerevisiae (strain ATCC 20... GCD11 - Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start...	0.0	[1..527]	[1..527]
gi\|169409549 - gi\|169409549\|gb\|ACA57895.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Calliceb... EF1A1_PANTR - Elongation factor 1-alpha 1 OS=Pan troglodytes GN=EEF1A1 PE=2 SV=1 gi\|163781003 - gi\|163781003\|gb\|ABY40784.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Papio an... gi\|67970565 - gi\|67970565\|dbj\|BAE01625.1\| unnamed protein product [Macaca fascicularis] EF1A1_PONAB - Elongation factor 1-alpha 1 OS=Pongo abelii GN=EEF1A1 PE=2 SV=2 EEF1A1 - eukaryotic translation elongation factor 1 alpha 1 gi\|60819043, gi\|... - gi\|61363070\|gb\|AAX42329.1\| eukaryotic translation elongation factor 1 alpha 1 [synthetic construct],... gi\|73973292 - gi\|73973292\|ref\|XP_532203.2\| PREDICTED: similar to eukaryotic translation elongation factor 1 alpha ... gi\|229368700 - gi\|229368700\|gb\|ACQ62985.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Dasypus ... tr\|F6UME7\|F6UME7... - Elongation factor 1-alpha OS=Equus caballus OX=9796 GN=EEF1A1 PE=3 SV=1 gi\|56342332\|dbj\|... - eukaryotic translation elongation factor 1 alpha 1 [Pan troglodytes] EF1A1_BOVIN - Elongation factor 1-alpha 1 OS=Bos taurus GN=EEF1A1 PE=1 SV=1 EF1A1_PONPY - Elongation factor 1-alpha 1 - Pongo pygmaeus (Orangutan) EF1A1_RABIT - Elongation factor 1-alpha 1 OS=Oryctolagus cuniculus GN=EEF1A1 PE=1 SV=1 gi\|109071708, gi... - gi\|109071710\|ref\|XP_001112777.1\| PREDICTED: similar to eukaryotic translation elongation factor 1 al... EF1A1_FELCA - Elongation factor 1-alpha 1 OS=Felis catus GN=EEF1A1 PE=2 SV=1 gi\|223019597, gi... - gi\|223019599\|emb\|CAX36487.1\| eukaryotic translation elongation factor 1 alpha 1 [Sus scrofa], gi\|223... ENSCJAT00000019570 - null	0.0	[96..527]	[3..448]
EF1A1_RAT - Elongation factor 1-alpha 1 OS=Rattus norvegicus GN=Eef1a1 PE=2 SV=1 gi\|190344037 - gi\|190344037\|gb\|ACE75815.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Sorex ar... EF1A1_MOUSE - Elongation factor 1-alpha 1 OS=Mus musculus GN=Eef1a1 PE=1 SV=3 gi\|183398094 - gi\|183398094\|gb\|ACC62508.1\| elongation factor 1 alpha (predicted) [Rhinolophus ferrumequinum] gi\|220279 - gi\|220279\|dbj\|BAA00409.1\| EF-1 alpha [Cricetulus longicaudatus] EF1A1_CRIGR - Elongation factor 1-alpha 1 OS=Cricetulus griseus GN=EEF1A1 PE=2 SV=1 gi\|53734423 - gb\|AAH84017.1\| Unknown (protein for MGC:98187) [Xenopus laevis]	0.0	[96..527]	[3..448]
gi\|15805031, gi\|... - gi\|15805031\|ref\|NP_284925.1\| eukaryotic translation elongation factor 1 alpha 2 [Rattus norvegicus],...	0.0	[96..527]	[3..448]
EF1A_CHICK - Elongation factor 1-alpha 1 OS=Gallus gallus GN=EEF1A PE=2 SV=1	0.0	[96..527]	[3..448]
EF1A0_XENLA - Elongation factor 1-alpha, somatic form OS=Xenopus laevis GN=eef1as PE=2 SV=1	0.0	[96..526]	[3..447]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[96..527]	[3..447]

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Predicted Domain #1

Region A:
Residues: [1-79]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLQDQEPS IIINGNLEPV GEPDIVEETE VVAQETQETQ DADKPKKKVA FTGLEEDGET  60
   61 EEEKRKREFE EGGGLPEQP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [80-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNPDFSKLNP LSAEIINRQA TINIGTIGHV AHGKSTVVRA ISGVQTVRFK DELERNITIK  60
   61 LGYANAKIYK CQEPTCPEPD CYRSFKSDKE ISPKCQRPGC PGRYKLVRHV SFVDCPGHDI 120
  121 LMSTMLSGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM KLKHVIILQN KVDLMREESA 180
  181 LEHQKSILKF IRGTIADGAP IVPISAQLKY NIDAVNEFIV KTIPVP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1113.0
Match:	1kk3A_
Description:	Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [306-424]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRDFMISPRL IVIRSFDVNK PGAEIEDLKG GVAGGSILNG VFKLGDEIEI RPGIVTKDDK  60
   61 GKIQCKPIFS NIVSLFAEQN DLKFAVPGGL IGVGTKVDPT LCRADRLVGQ VVGAKGHLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1113.0
Match:	1kk3A_
Description:	Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [425-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIYTDIEINY FLLRRLLGVK TDGQKQAKVR KLEPNEVLMV NIGSTATGAR VVAVKADMAR  60
   61 LQLTSPACTE INEKIALSRR IEKHWRLIGW ATIKKGTTLE PIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1113.0
Match:	1kk3A_
Description:	Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits