YRC Public Data Repository - Protein Structure Prediction

Protein:	GCD11
Organism:	Saccharomyces cerevisiae
Length:	527 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCD11.

Description	E-value	Query Range	Subject Range
gi\|151944735 - gi\|151944735\|gb\|EDN62994.1\| translational initiation factor eIF-2 gamma subunit [Saccharomyces cerev... gi\|190405587 - gi\|190405587\|gb\|EDV08854.1\| translational initiation factor eIF-2 gamma subunit [Saccharomyces cerev... gi\|207346006 - gi\|207346006\|gb\|EDZ72633.1\| YER025Wp-like protein [Saccharomyces cerevisiae AWRI1631] IF2G_YEAST - Eukaryotic translation initiation factor 2 subunit gamma OS=Saccharomyces cerevisiae (strain ATCC 20... GCD11 - Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start...	0.0	[1..527]	[1..527]
gi\|169409549 - gi\|169409549\|gb\|ACA57895.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Calliceb... EF1A1_PANTR - Elongation factor 1-alpha 1 OS=Pan troglodytes GN=EEF1A1 PE=2 SV=1 gi\|163781003 - gi\|163781003\|gb\|ABY40784.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Papio an... gi\|67970565 - gi\|67970565\|dbj\|BAE01625.1\| unnamed protein product [Macaca fascicularis] EF1A1_PONAB - Elongation factor 1-alpha 1 OS=Pongo abelii GN=EEF1A1 PE=2 SV=2 EEF1A1 - eukaryotic translation elongation factor 1 alpha 1 gi\|60819043, gi\|... - gi\|61363070\|gb\|AAX42329.1\| eukaryotic translation elongation factor 1 alpha 1 [synthetic construct],... gi\|73973292 - gi\|73973292\|ref\|XP_532203.2\| PREDICTED: similar to eukaryotic translation elongation factor 1 alpha ... gi\|229368700 - gi\|229368700\|gb\|ACQ62985.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Dasypus ... tr\|F6UME7\|F6UME7... - Elongation factor 1-alpha OS=Equus caballus OX=9796 GN=EEF1A1 PE=3 SV=1 gi\|56342332\|dbj\|... - eukaryotic translation elongation factor 1 alpha 1 [Pan troglodytes] EF1A1_BOVIN - Elongation factor 1-alpha 1 OS=Bos taurus GN=EEF1A1 PE=1 SV=1 EF1A1_PONPY - Elongation factor 1-alpha 1 - Pongo pygmaeus (Orangutan) EF1A1_RABIT - Elongation factor 1-alpha 1 OS=Oryctolagus cuniculus GN=EEF1A1 PE=1 SV=1 gi\|109071708, gi... - gi\|109071710\|ref\|XP_001112777.1\| PREDICTED: similar to eukaryotic translation elongation factor 1 al... EF1A1_FELCA - Elongation factor 1-alpha 1 OS=Felis catus GN=EEF1A1 PE=2 SV=1 gi\|223019597, gi... - gi\|223019599\|emb\|CAX36487.1\| eukaryotic translation elongation factor 1 alpha 1 [Sus scrofa], gi\|223... ENSCJAT00000019570 - null	0.0	[96..527]	[3..448]
EF1A1_RAT - Elongation factor 1-alpha 1 OS=Rattus norvegicus GN=Eef1a1 PE=2 SV=1 gi\|190344037 - gi\|190344037\|gb\|ACE75815.1\| eukaryotic translation elongation factor 1 alpha 1 (predicted) [Sorex ar... EF1A1_MOUSE - Elongation factor 1-alpha 1 OS=Mus musculus GN=Eef1a1 PE=1 SV=3 gi\|183398094 - gi\|183398094\|gb\|ACC62508.1\| elongation factor 1 alpha (predicted) [Rhinolophus ferrumequinum] gi\|220279 - gi\|220279\|dbj\|BAA00409.1\| EF-1 alpha [Cricetulus longicaudatus] EF1A1_CRIGR - Elongation factor 1-alpha 1 OS=Cricetulus griseus GN=EEF1A1 PE=2 SV=1 gi\|53734423 - gb\|AAH84017.1\| Unknown (protein for MGC:98187) [Xenopus laevis]	0.0	[96..527]	[3..448]
gi\|15805031, gi\|... - gi\|15805031\|ref\|NP_284925.1\| eukaryotic translation elongation factor 1 alpha 2 [Rattus norvegicus],...	0.0	[96..527]	[3..448]
EF1A_CHICK - Elongation factor 1-alpha 1 OS=Gallus gallus GN=EEF1A PE=2 SV=1	0.0	[96..527]	[3..448]
EF1A0_XENLA - Elongation factor 1-alpha, somatic form OS=Xenopus laevis GN=eef1as PE=2 SV=1	0.0	[96..526]	[3..447]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[96..527]	[3..447]

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Predicted Domain #1

Region A:
Residues: [1-79]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLQDQEPS IIINGNLEPV GEPDIVEETE VVAQETQETQ DADKPKKKVA FTGLEEDGET  60
   61 EEEKRKREFE EGGGLPEQP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.231	a.2.2	Ribosomal protein L29 (L29p)
View	Download	0.486	d.74.2	C-terminal domain of arginine repressor
View	Download	0.262	a.28.2	Colicin E immunity proteins
View	Download	0.486	d.74.2	C-terminal domain of arginine repressor
View	Download	0.262	a.28.2	Colicin E immunity proteins
View	Download	0.262	d.58.36	Sulfite reductase, domains 1 and 3
View	Download	0.262	d.58.36	Sulfite reductase, domains 1 and 3
View	Download	0.231	a.2.2	Ribosomal protein L29 (L29p)

Predicted Domain #2

Region A:
Residues: [80-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNPDFSKLNP LSAEIINRQA TINIGTIGHV AHGKSTVVRA ISGVQTVRFK DELERNITIK  60
   61 LGYANAKIYK CQEPTCPEPD CYRSFKSDKE ISPKCQRPGC PGRYKLVRHV SFVDCPGHDI 120
  121 LMSTMLSGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM KLKHVIILQN KVDLMREESA 180
  181 LEHQKSILKF IRGTIADGAP IVPISAQLKY NIDAVNEFIV KTIPVP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1113.0
Match:	1kk3A_
Description:	Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [306-424]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRDFMISPRL IVIRSFDVNK PGAEIEDLKG GVAGGSILNG VFKLGDEIEI RPGIVTKDDK  60
   61 GKIQCKPIFS NIVSLFAEQN DLKFAVPGGL IGVGTKVDPT LCRADRLVGQ VVGAKGHLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1113.0
Match:	1kk3A_
Description:	Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [425-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIYTDIEINY FLLRRLLGVK TDGQKQAKVR KLEPNEVLMV NIGSTATGAR VVAVKADMAR  60
   61 LQLTSPACTE INEKIALSRR IEKHWRLIGW ATIKKGTTLE PIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1113.0
Match:	1kk3A_
Description:	Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits