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View Structure Prediction Details

Protein: SPC25
Organism: Saccharomyces cerevisiae
Length: 221 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPC25.

Description E-value Query
Range
Subject
Range
SPC25 - Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-...
SPC25_YEAST - Kinetochore protein SPC25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPC25 PE=1 SV=...
gi|151944727 - gi|151944727|gb|EDN62986.1| spindle pole component [Saccharomyces cerevisiae YJM789]
2.0E-55 [1..221] [1..221]
K2C8_BOVIN - (P05786) Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keraton-8) (K8) (Cytokeratin-A) (Fr...
1.0E-34 [2..133] [218..365]
KRT84 - keratin 84
1.0E-34 [2..156] [393..546]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-32 [2..105] [319..422]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASIDAFSDL ERRMDGFQKD VAQVLARQQN HARQQLQQFQ AEMRQLHNQH QHLIDELQRL  60
   61 ATQRTALQQQ IHAAQQATNT TREQWRSYHE RESELSRRQS TLAAQSRELD SLLQQRGKEC 120
  121 VQLRARWAAQ SGNDAAEVAL YERLLQLRVL P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1gk4A_
Description: Vimentin coil
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [152-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GASDVHDVRF VFGDDSRCWI EVAMHGDHVI GNSHPALDPK SRATLEHVLT VQGDLAAFLV  60
   61 VARDMLLASL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle