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View Structure Prediction Details

Protein: NTF2
Organism: Saccharomyces cerevisiae
Length: 125 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTF2.

Description E-value Query
gi|25310685, gi|... - gi|9802547|gb|AAF99749.1|AC004557_28 F17L21.10 [Arabidopsis thaliana], pir||H86398 protein F17L21.10...
1.0E-40 [3..124] [1..122]
gi|223640932, gi... - gi|241949743|ref|XP_002417594.1| nuclear transport factor 2, putative [Candida dubliniensis CD36], g...
NTF2_CANAX - Nuclear transport factor 2 OS=Candida albicans GN=NTF2 PE=3 SV=1
1.0E-40 [1..124] [1..124]
ORFP:6054 - YER009W, Contig c425 25784-26161
gi|190405570 - gi|190405570|gb|EDV08837.1| nuclear transport factor [Saccharomyces cerevisiae RM11-1a]
NTF2_YEAST - Nuclear transport factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTF2 PE=1 SV=...
NTF2 - Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to tr...
gi|151944717 - gi|151944717|gb|EDN62976.1| nuclear transport factor [Saccharomyces cerevisiae YJM789]
3.0E-40 [1..125] [1..125]
gi|125562321 - gi|125562321|gb|EAZ07769.1| hypothetical protein OsI_30022 [Oryza sativa Indica Group]
NTF2_ORYSA - Nuclear transport factor 2 (NTF-2) - Oryza sativa (Rice)
NTF2_ORYSJ - Nuclear transport factor 2 OS=Oryza sativa subsp. japonica GN=NTF2 PE=2 SV=1
3.0E-40 [3..123] [1..121]
gi|7246005, gi|7... - gi|7246008|pdb|1QMA|D Chain D, Nuclear Transport Factor 2 (Ntf2) W7a Mutant, gi|7246007|pdb|1QMA|C C...
5.0E-40 [5..121] [6..120]
tr|M3X0F5|M3X0F5... - Nuclear transport factor 2 OS=Felis catus GN=NUTF2 PE=4 SV=1
NUTF2 - nuclear transport factor 2
CCDS10848.1_1 - null
ENSCJAT00000031145 - null
gi|149699240 - gi|149699240|ref|XP_001498298.1| PREDICTED: similar to Nuclear transport factor 2 (NTF-2) (Placental...
HGNC:13722|MIM:6... - transport factor 2
tr|G1SQR7|G1SQR7... - pep:novel chromosome:oryCun2:2:69386170:69386553:1 gene:ENSOCUG00000025641 transcript:ENSOCUT0000002...
NTF2_BOVIN - Nuclear transport factor 2 OS=Bos taurus GN=NUTF2 PE=2 SV=1
tr|G3HKX2|G3HKX2... - Nuclear transport factor 2 OS=Cricetulus griseus GN=I79_011354 PE=4 SV=1
gi|57087201, gi|... - gi|73957289|ref|XP_864539.1| PREDICTED: similar to Nuclear transport factor 2 (NTF-2) isoform 3 [Can...
gi|90081342 - gi|90081342|dbj|BAE90151.1| unnamed protein product [Macaca fascicularis]
NTF2_RAT - Nuclear transport factor 2 OS=Rattus norvegicus GN=Nutf2 PE=1 SV=1
gi|190689363, gi... - gi|190690725|gb|ACE87137.1| nuclear transport factor 2 protein [synthetic construct], gi|190689363|g...
NTF2_MOUSE - Nuclear transport factor 2 OS=Mus musculus GN=Nutf2 PE=1 SV=1
gi|114663219, gi... - gi|55644067|ref|XP_511042.1| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes], gi|1146632...
5.0E-40 [6..121] [8..121]
NTF2_EMENI - Nuclear transport factor 2 OS=Emericella nidulans GN=ntf2 PE=3 SV=1
NTF2_EMENI - Nuclear transport factor 2 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 1...
1.0E-37 [4..125] [3..125]


Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
  121 LNYSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 630.045757
Match: 1gy7A_
Description: Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein transporter activity 3.2858716221712 bayes_pls_golite062009
nucleocytoplasmic transporter activity 2.57260151088345 bayes_pls_golite062009
binding 2.32562999055027 bayes_pls_golite062009
protein transmembrane transporter activity 2.22367856601071 bayes_pls_golite062009
transporter activity 1.80701285041353 bayes_pls_golite062009
substrate-specific transporter activity 1.33804818542017 bayes_pls_golite062009
structural constituent of nuclear pore 1.30758304562723 bayes_pls_golite062009
protein binding 1.24260899146543 bayes_pls_golite062009
transmembrane transporter activity 1.22102896992563 bayes_pls_golite062009
Ran GTPase binding 1.18290069522408 bayes_pls_golite062009
RNA binding 1.05240446104847 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.890150150408175 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.79772386064313 bayes_pls_golite062009
macromolecule transmembrane transporter activity 0.79772386064313 bayes_pls_golite062009
nucleic acid binding 0.688410645367506 bayes_pls_golite062009
primary active transmembrane transporter activity 0.446562877324676 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.439519001457896 bayes_pls_golite062009
active transmembrane transporter activity 0.430285640125175 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle