YRC Public Data Repository - Protein Structure Prediction

Protein:	YND1
Organism:	Saccharomyces cerevisiae
Length:	630 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YND1.

Description	E-value	Query Range	Subject Range
YND1 - Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by h... YND1_YEAST - Golgi apyrase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YND1 PE=1 SV=1 gi\|190405565 - gi\|190405565\|gb\|EDV08832.1\| golgi apyrase [Saccharomyces cerevisiae RM11-1a]	0.0	[1..630]	[1..630]
gi\|55664712, gi\|... - gi\|55958874\|emb\|CAI16771.1\| ectonucleoside triphosphate diphosphohydrolase 1 [Homo sapiens], gi\|5566...	0.0	[5..451]	[51..467]
gi\|765257 - gi\|765257\|gb\|AAB32153.1\| lymphoid cell activation antigen, CD39=guanosine-diphosphatase homolog [mic... ENTP1_MOUSE - Ectonucleoside triphosphate diphosphohydrolase 1 OS=Mus musculus GN=Entpd1 PE=1 SV=1	0.0	[5..451]	[44..460]
ENTP1_RAT - Ectonucleoside triphosphate diphosphohydrolase 1 OS=Rattus norvegicus GN=Entpd1 PE=1 SV=1	0.0	[5..451]	[44..461]
ENTP1_BOVIN - Ectonucleoside triphosphate diphosphohydrolase 1 OS=Bos taurus GN=ENTPD1 PE=1 SV=1	0.0	[5..451]	[44..463]

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Predicted Domain #1

Region A:
Residues: [1-499]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIENTNDRF GIVIDAGSSG SRIHVFKWQD TESLLHATNQ DSQSILQSVP HIHQEKDWTF  60
   61 KLNPGLSSFE KKPQDAYKSH IKPLLDFAKN IIPESHWSSC PVFIQATAGM RLLPQDIQSS 120
  121 ILDGLCQGLK HPAEFLVEDC SAQIQVIDGE TEGLYGWLGL NYLYGHFNDY NPEVSDHFTF 180
  181 GFMDMGGAST QIAFAPHDSG EIARHRDDIA TIFLRSVNGD LQKWDVFVST WLGFGANQAR 240
  241 RRYLAQLINT LPENTNDYEN DDFSTRNLND PCMPRGSSTD FEFKDTIFHI AGSGNYEQCT 300
  301 KSIYPLLLKN MPCDDEPCLF NGVHAPRIDF ANDKFIGTSE YWYTANDVFK LGGEYNFDKF 360
  361 SKSLREFCNS NWTQILANSD KGVYNSIPEN FLKDACFKGN WVLNILHEGF DMPRIDVDAE 420
  421 NVNDRPLFQS VEKVEERELS WTLGRILLYA SGSILAGNDD FMVGIAPSER RTKLTGKKFI 480
  481 PGKLLESDQL RKQSSSLSN

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	287.420216
Match:	PF01150
Description:	GDA1/CD39 (nucleoside phosphatase) family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
substrate-specific transporter activity	2.6067350860805	bayes_pls_golite062009
binding	1.67810028738512	bayes_pls_golite062009
kinase activity	1.49017495306118	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.41202247176912	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.17094423081025	bayes_pls_golite062009
carbohydrate kinase activity	0.918413613159579	bayes_pls_golite062009
protein binding	0.909114722614987	bayes_pls_golite062009
peptide binding	0.512219022453579	bayes_pls_golite062009
hexokinase activity	0.3464071310254	bayes_pls_golite062009
catalytic activity	0.308539563780047	bayes_pls_golite062009
structural molecule activity	0.27696059113386	bayes_pls_golite062009
protein kinase activity	0.273427627634136	bayes_pls_golite062009
nucleic acid binding	0.157726298952452	bayes_pls_golite062009
glucokinase activity	0.0827631486617343	bayes_pls_golite062009
transcription regulator activity	0.0562867443774764	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.0272188887044016	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [500-630]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGFLMWFAII CCIFYLIFHR SHIIRRRFSG LYNITKDFKT GIRRRLKFLR RSDPFSRLEE  60
   61 GELGTDVDGF KDVYRMKSSS MFDLGKSSAT MQREHEPQRT ASQSANLAPS NLRPAFSMAD 120
  121 FSKFKDSRLY D

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [384-450]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNSIPENFLK DACFKGNWVL NILHEGFDMP RIDVDAENVN DRPLFQSVEK VEERELSWTL  60
   61 GRILLYA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [451-630]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSILAGNDD FMVGIAPSER RTKLTGKKFI PGKLLESDQL RKQSSSLSNK GFLMWFAIIC  60
   61 CIFYLIFHRS HIIRRRFSGL YNITKDFKTG IRRRLKFLRR SDPFSRLEEG ELGTDVDGFK 120
  121 DVYRMKSSSM FDLGKSSATM QREHEPQRTA SQSANLAPSN LRPAFSMADF SKFKDSRLYD 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: