YRC Public Data Repository - Protein Structure Prediction

Protein:	SPF1
Organism:	Saccharomyces cerevisiae
Length:	1215 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPF1.

Description	E-value	Query Range	Subject Range
ATC6_YEAST - Manganese-transporting ATPase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPF1 PE=... SPF1 - P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; requ... gi\|151944679 - gi\|151944679\|gb\|EDN62938.1\| ion-translocating ATPase [Saccharomyces cerevisiae YJM789]	0.0	[1..1215]	[1..1215]
AT1A1_HORSE - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Equus caballus GN=ATP1A1 PE=3 SV=1	0.0	[107..1068]	[5..999]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[108..1068]	[6..999]
gi\|89248 - pir\|\|B24862 Na+/K+-exchanging ATPase (EC 3.6.3.9) alpha chain - pig AT1A1_PIG - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Sus scrofa GN=ATP1A1 PE=1 SV=1	0.0	[108..1068]	[6..999]
AT1A1_SHEEP - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Ovis aries GN=ATP1A1 PE=1 SV=1	0.0	[108..1068]	[6..999]
gi\|11067034 - gi\|11067034\|gb\|AAG27060.1\| Na+/K+ ATPase alpha subunit isoform 8 [Danio rerio]	0.0	[108..1068]	[6..1002]
AT1A3_CHICK - Sodium/potassium-transporting ATPase subunit alpha-3 OS=Gallus gallus GN=ATP1A3 PE=2 SV=1	0.0	[119..1075]	[1..988]
AT1A1_MOUSE - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Mus musculus GN=Atp1a1 PE=1 SV=1	0.0	[108..1068]	[6..1001]
AT1A1_RAT - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Rattus norvegicus GN=Atp1a1 PE=1 SV=1	0.0	[108..1068]	[6..1001]

Back

Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKKSFVSSP IVRDSTLLVP KSLIAKPYVL PFFPLYATFA QLYFQQYDRY IKGPEWTFVY  60
   61 LGTLVSLNIL VMLMPAWNVK IKAKFNYSTT KNVNEATHIL IYTTPNNGSD GIVEIQRVTE 120
  121 AGSLQTFFQF QKKRFLWHEN E

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [142-183]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVFSSPKFLV DESPKIGDFQ KCKGHSGDLT HLKRLYGENS FD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [254-389]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTINVFRNKK WVALQTNELL PMDLVSITRT AEESAIPCDL ILLDGSAIVN EAMLSGESTP  60
   61 LLKESIKLRP SEDNLQLDGV DKIAVLHGGT KALQVTPPEH KSDIPPPPDG GALAIVTKTG 120
  121 FETSQGSLVR VMIYSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1170.0
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #3

Region A:
Residues: [184-244]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPIPTFMELF KEHAVAPLFV FQVFCVALWL LDEFWYYSLF NLFMIISMEA AAVFQRLTAL  60
   61 K

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [390-454]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERVSVDNKEA LMFILFLLIF AVIASWYVWV EGTKMGRIQS KLILDCILII TSVVPPELPM  60
   61 ELTMA

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [862-1092]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFMARWNQPQ PPVPEPIAHL FPPGPKNPHY LKALESKGTV ITPEIRKAVE EANSKPVEVI  60
   61 KPNGLSEKKP ADLASLLLNS AGDAQGDEAP ALKLGDASCA APFTSKLANV SAVTNIIRQG 120
  121 RCALVNTIQM YKILALNCLI SAYSLSIIYM AGVKFGDGQA TVSGLLLSVC FLSISRGKPL 180
  181 EKLSKQRPQS GIFNVYIMGS ILSQFAVHIA TLVYITTEIY KLEPREPQVD L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1170.0
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #4

Region A:
Residues: [245-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFRTMGIKP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [455-494]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNSSLAALAK FYVYCTEPFR IPFAGRIDVC CFDKTGTLTG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [675-861]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKDDAIETIK MLNESSHRSI MITGDNPLTA VHVAKEVGIV FGETLILDRA GKSDDNQLLF  60
   61 RDVEETVSIP FDPSKDTFDH SKLFDRYDIA VTGYALNALE GHSQLRDLLR HTWVYARVSP 120
  121 SQKEFLLNTL KDMGYQTLMC GDGTNDVGAL KQAHVGIALL NGTEEGLKKL GEQRRLEGMK 180
  181 MMYIKQT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1170.0
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #5

Region A:
Residues: [495-674]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDLVFEGLAG ISADSENIRH LYSAAEAPES TILVIGAAHA LVKLEDGDIV GDPMEKATLK  60
   61 AVGWAVERKN SNYREGTGKL DIIRRFQFSS ALKRSASIAS HNDALFAAVK GAPETIRERL 120
  121 SDIPKNYDEI YKSFTRSGSR VLALASKSLP KMSQSKIDDL NRDDVESELT FNGFLIFHCP 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1170.0
Match:	1eulA_
Description:	Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #6

Region A:
Residues: [1093-1215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKEFAPSLLN TGIFIIQLVQ QVSTFAVNYQ GEPFRENIRS NKGMYYGLLG VTGLALASAT  60
   61 EFLPELNEAM KFVPMTDDFK IKLTLTLLLD FFGSWGVEHF FKFFFMDDKP SDISVQQVKI 120
  121 ASK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits