YRC Public Data Repository - Protein Structure Prediction

Protein:	EDC3
Organism:	Saccharomyces cerevisiae
Length:	551 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EDC3.

Description	E-value	Query Range	Subject Range
gi\|190405551 - gi\|190405551\|gb\|EDV08818.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207346060 - gi\|207346060\|gb\|EDZ72672.1\| YEL015Wp-like protein [Saccharomyces cerevisiae AWRI1631] EDC3 - Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically ... EDC3_YEAST - Enhancer of mRNA-decapping protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EDC...	0.0	[1..551]	[1..551]
EDC3_SCHPO - Enhancer of mRNA-decapping protein 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=edc3 ... edc3 - enhancer of mRNA decapping Edc3	1.0E-62	[197..492]	[116..410]
gi\|29140293, gi\|... - gi\|29144654\|ref\|NP_807996.1\| hypothetical protein t4406 [Salmonella enterica subsp. enterica serovar... gi\|16505483, gi\|... - gi\|25344769\|pir\|\|AD1048 conserved hypothetical protein yjeF [imported] - Salmonella enterica subsp. ... gi\|213647296 - gi\|213647296\|ref\|ZP_03377349.1\| hypothetical protein SentesTy_08323 [Salmonella enterica subsp. ente... gi\|213052285 - gi\|213052285\|ref\|ZP_03345163.1\| hypothetical protein Salmoneentericaenterica_04742 [Salmonella enter... gi\|16763175 - gi\|16763175\|ref\|NP_458792.1\| hypothetical protein STY4713 [Salmonella enterica subsp. enterica serov...	1.0E-53	[290..540]	[23..238]
gi\|238903274, gi... - gi\|238903274\|ref\|YP_002929070.1\| putative carbohydrate kinase [Escherichia coli BW2952], gi\|23886218... gi\|218363488, gi... - gi\|218556719\|ref\|YP_002389633.1\| hypothetical protein ECIAI1_4400 [Escherichia coli IAI1], gi\|218363... EG11758 - bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehy... gi\|254037180, gi... - gi\|254037180\|ref\|ZP_04871257.1\| conserved hypothetical protein [Escherichia sp. 1_1_43], gi\|22684028... YJEF_ECOLI - Hypothetical protein yjeF - Escherichia coli gi\|170083613, gi... - gi\|170083613\|ref\|YP_001732933.1\| carbohydrate kinase [Escherichia coli str. K-12 substr. DH10B], gi\|... EG11758 - bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehy... gi\|89110887, gi\|... - gi\|89110887\|ref\|AP_004667.1\| predicted carbohydrate kinase [Escherichia coli str. K-12 substr. W3110...	1.0E-53	[290..540]	[23..238]
lcl\|NC_016856.1_... - [gene=yjeF] [protein=hypothetical protein] [protein_id=YP_005240668.1] [location=4611198..4612745] gi\|16422916, gi\|... - gi\|16767602\|ref\|NP_463217.1\| hypothetical protein STM4356 [Salmonella typhimurium LT2], gi\|16422916\|...	2.0E-53	[290..540]	[23..238]
gi\|254796186, gi... - gi\|254796186\|ref\|YP_003081023.1\| predicted carbohydrate kinase [Escherichia coli O157:H7 str. TW1435... gi\|15834397, gi\|... - gi\|15834397\|ref\|NP_313170.1\| hypothetical protein ECs5142 [Escherichia coli O157:H7], gi\|13364620\|db... gi\|195935957 - gi\|195935957\|ref\|ZP_03081339.1\| hypothetical protein EscherichcoliO157_05740 [Escherichia coli O157:... gi\|209750340, gi... - pir\|\|G91271 hypothetical protein ECs5142 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|15834397, gi\|... - gi\|15834397\|ref\|NP_313170.1\| hypothetical protein ECs5142 [Escherichia coli O157:H7 str. Sakai], gi\|...	1.0E-52	[290..540]	[23..238]
NNR_PYRAE - Bifunctional NAD(P)H-hydrate repair enzyme Nnr OS=Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / ...	3.0E-52	[291..525]	[9..215]
gi\|15804756, gi\|... - gi\|15804756\|ref\|NP_290797.1\| hypothetical protein Z5774 [Escherichia coli O157:H7 EDL933], gi\|125191... gi\|25344764 - pir\|\|G86112 hypothetical protein yjeF [imported] - Escherichia coli (strain O157:H7, substrain EDL9...	1.0E-51	[290..540]	[23..238]
NNR_ARCFU - Bifunctional NAD(P)H-hydrate repair enzyme Nnr OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... gi\|7483058 - pir\|\|C69356 conserved hypothetical protein AF0851 - Archaeoglobus fulgidus	2.0E-50	[286..525]	[4..199]
gi\|18892133, gi\|... - gi\|18976572\|ref\|NP_577929.1\| hypothetical protein PF0200 [Pyrococcus furiosus DSM 3638], gi\|18892133...	1.0E-48	[295..526]	[10..202]

Back

Predicted Domain #1

Region A:
Residues: [1-265]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQFVGFGVQ VELKDGKLIQ GKIAKATSKG LTLNDVQFGD GGKSQAFKVR ASRLKDLKVL  60
   61 TVASQSGKRK QQRQQQQQND YNQNRGEHID WQDDDVSKIK QQEDFDFQRN LGMFNKKDVF 120
  121 AQLKQNDDIL PENRLQGHNR KQTQLQQNNY QNDELVIPDA KKDSWNKISS RNEQSTHQSQ 180
  181 PQQDAQDDLV LEDDEHEYDV DDIDDPKYLP ITQSLNITHL IHSATNSPSI NDKTKGTVIN 240
  241 DKDQVLAKLG QMIISQSRSN STSLP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [266-551]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AANKQTTIRS KNTKQNIPMA TPVQLLEMES ITSEFFSINS AGLLENFAVN ASFFLKQKLG  60
   61 GRARLRLQNS NPEPLVVILA SDSNRSGAKA LALGRHLCQT GHIRVITLFT CSQNELQDSM 120
  121 VKKQTDIYKK CGGKIVNSVS SLESAMETLN SPVEIVIDAM QGYDCTLSDL AGTSEVIESR 180
  181 IKSMISWCNK QRGSTKVWSL DIPNGFDAGS GMPDIFFSDR IEATGIICSG WPLIAINNLI 240
  241 ANLPSLEDAV LIDIGIPQGA YSQRTSLRKF QNCDLFVTDG SLLLDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.39794
Match:	1jztA_
Description:	Hypothetical protein YNL200c (YNU0 YEAST)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [276-551]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNTKQNIPMA TPVQLLEMES ITSEFFSINS AGLLENFAVN ASFFLKQKLG GRARLRLQNS  60
   61 NPEPLVVILA SDSNRSGAKA LALGRHLCQT GHIRVITLFT CSQNELQDSM VKKQTDIYKK 120
  121 CGGKIVNSVS SLESAMETLN SPVEIVIDAM QGYDCTLSDL AGTSEVIESR IKSMISWCNK 180
  181 QRGSTKVWSL DIPNGFDAGS GMPDIFFSDR IEATGIICSG WPLIAINNLI ANLPSLEDAV 240
  241 LIDIGIPQGA YSQRTSLRKF QNCDLFVTDG SLLLDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.69897
Match:	1jztA
Description:	Hypothetical protein YNL200c (YNU0 YEAST)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits