YRC Public Data Repository - Protein Structure Prediction

Protein:	TLG1
Organism:	Saccharomyces cerevisiae
Length:	224 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TLG1.

Description	E-value	Query Range	Subject Range
gi\|18175840 - gi\|18175840\|gb\|AAL59937.1\| unknown protein [Arabidopsis thaliana]	1.0E-36	[1..223]	[1..244]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-35	[20..217]	[39..250]
gi\|3123708, gi\|9... - gi\|9625039\|ref\|NP_062506.1\| syntaxin 1B1 [Mus musculus], gi\|3123708\|dbj\|BAA25986.1\| syntaxin1B [Mus ...	3.0E-34	[20..217]	[67..278]
STX1B_MOUSE - Syntaxin-1B OS=Mus musculus GN=Stx1b PE=1 SV=1 gi\|251471 - gi\|251471\|gb\|AAB22526.1\| syntaxin, P35B [rats, brain, Peptide, 288 aa] ENSCJAT00000005845 - null gi\|114662156 - gi\|114662156\|ref\|XP_001145497.1\| PREDICTED: similar to syntaxin B [Pan troglodytes] STX1B - syntaxin 1B STX1B_RAT - Syntaxin-1B OS=Rattus norvegicus GN=Stx1b PE=1 SV=1	2.0E-33	[20..217]	[67..278]
gi\|1923254 - gi\|1923254\|gb\|AAC47500.1\| syntaxin 1 homolog [Hirudo medicinalis]	5.0E-33	[4..219]	[49..285]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	5.0E-33	[20..217]	[67..278]

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Predicted Domain #1

Region A:
Residues: [1-93]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSEDPFQQ VVKDTKEQLN RINNYITRHN TAGDDDQEEE IQDILKDVEE TIVDLDRSII  60
   61 VMKRDENEDV SGREAQVKNI KQQLDALKLR FDR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [140-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHLDGIHKTM QNLHIQAQTM GDELENQGQL LDNMDEGMDG VVNKLARGRR QLEWVYEKNK  60
   61 EKYDDCCIGL LIVVLIVLLV LAFIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.0
Match:	1dn1B_
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [94-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIQESTQTTI PLEETVENST LNTSMAENND GGMSNPFQEQ MLREQD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.0
Match:	1dn1B_
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits