YRC Public Data Repository - Protein Structure Prediction

Protein:	PFA5
Organism:	Saccharomyces cerevisiae
Length:	374 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFA5.

Description	E-value	Query Range	Subject Range
PFA5_YEAST - Palmitoyltransferase PFA5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFA5 PE=1 SV=1 PFA5 - Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member... gi\|151942423 - gi\|151942423\|gb\|EDN60779.1\| palmitoyltransferase [Saccharomyces cerevisiae YJM789] gi\|207346251 - gi\|207346251\|gb\|EDZ72803.1\| YDR459Cp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190404618 - gi\|190404618\|gb\|EDV07885.1\| palmitoyltransferase [Saccharomyces cerevisiae RM11-1a]	1.0E-85	[1..374]	[1..374]
ZDH23_ARATH - Probable protein S-acyltransferase 6 OS=Arabidopsis thaliana GN=PAT06 PE=2 SV=1	4.0E-76	[3..366]	[24..395]
gi\|220942256 - gi\|220942256\|gb\|ACL83671.1\| CG1407-PB [synthetic construct] CG1407-PB - This gene is referred to in FlyBase by the symbol Dmel\CG1407 (CG1407, FBgn0033474). It is a protein...	5.0E-61	[10..352]	[15..326]
gi\|85719324, gi\|... - gi\|85719324\|ref\|NP_083768.4\| DHHC-containing protein 20 [Mus musculus], gi\|74190231\|dbj\|BAE37221.1\| ...	1.0E-60	[1..331]	[1..300]
ZDHHC2 - zinc finger, DHHC-type containing 2	3.0E-58	[1..334]	[1..301]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALSWNIRIR RRSWFRFILP IIVLGLLCYG TWAYCHKLCY EQVDKRLRQK SVSVGLICAV  60
   61 CFLDVVVIFI WLQIVILVGP GTQPHVAPFL ILPIASEEKT S

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.882	0.000	zinc ion binding	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

Predicted Domain #2

Region A:
Residues: [102-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTSQNTSVEY DAVVPPKCYQ SDPHGYPIWC SECQSLKMER THHSSELGHC IPRFDHYCMW  60
   61 IGTVIGRDNY RLFVQFAAYF STLLLIMWVS ICVYIRIITQ HNHNYS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	33.420216
Match:	PF01529
Description:	DHHC zinc finger domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [208-374]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLNANIIST LVFAILGWLL TASLLASSIF YMSQNKTSLE AIIDSKRKKF GTRKIFCYYS  60
   61 EANKLRFVVE FDRSEFHSFW DKKSILANIK DFMGSNILMW IIPLGKPYTS RCKSDGKSGS 120
  121 KTTLVEILGP YEETLSDYTI QAIEDKISRG EYLATLRASG DDSDPAY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits