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View Structure Prediction Details

Protein: EAF1
Organism: Saccharomyces cerevisiae
Length: 959 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EAF1.

Description E-value Query
Range
Subject
Range
SPCC1795.08c - histone acetyltransferase complex subunit
EAF_SCHPO - Chromatin modification-related protein vid21 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
2.0E-68 [631..834] [695..908]
gi|7959257 - gi|7959257|dbj|BAA96022.1| KIAA1498 protein [Homo sapiens]
2.0E-27 [326..396] [745..814]
gi|14090511 - gi|14090511|gb|AAK53539.1| DOMINO B [Drosophila melanogaster]
1.0E-20 [318..396] [483..557]
gi|11994423 - gi|11994423|dbj|BAB02425.1| helicase-like protein [Arabidopsis thaliana]
9.0E-12 [351..388] [40..77]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRPSSAVP NSASLSEDQS SDRSKFPKAD DLIDERDRKL TELYCVSRLN QLLELTDENK  60
   61 LRKEIDAFLK KNDIRRGIRF DEASLPKLLH TAATPITKKK LKDVNLINVP NQRLSDSKMS 120
  121 RELPENSENV SVKSESHFVP SHDNSIRENM MDSLRPAEKT GGMWNKRPLE STMGGEEERH 180
  181 EKRQKMQSQS LESSNNSEMA SLPISPRPPV PNALAHYTYY ENIEYPPADP TEVQPAVKFK 240
  241 DPLIKNIMAK EIDTSDHYN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [260-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENNVDALETV FLLMNDYIPS KIPQALPLAE LKYMSQTLPL INLIPRAHKA LTTNIINNAL  60
   61 NEARITVVGS RIEELRRLGL WSLRQPKRFI DPWKQHNTHQ NILLEEAKWM QADFKEGHKY 120
  121 KVAICTAMAQ AIKDYWTYGE ICCVKRK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.516 0.250 histone acetyltransferase complex a.1.1 Globin-like
View Download 0.689 0.247 histone acetyltransferase complex d.19.1 MHC antigen-recognition domain
View Download 0.451 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.388 N/A N/A a.2.5 Prefoldin
View Download 0.381 N/A N/A a.47.2 t-snare proteins
View Download 0.344 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.332 N/A N/A a.7.1 Spectrin repeat
View Download 0.329 N/A N/A a.74.1 Cyclin-like
View Download 0.302 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.289 N/A N/A a.25.1 Ferritin-like
View Download 0.270 N/A N/A a.24.3 Cytochromes
View Download 0.263 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.254 N/A N/A a.24.1 Apolipoprotein
View Download 0.245 N/A N/A a.1.1 Globin-like
View Download 0.244 N/A N/A a.2.5 Prefoldin
View Download 0.239 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.226 N/A N/A a.182.1 GatB/YqeY domain
View Download 0.219 N/A N/A c.23.1 CheY-like
View Download 0.214 N/A N/A a.7.1 Spectrin repeat
View Download 0.210 N/A N/A d.110.2 GAF domain-like

Predicted Domain #3
Region A:
Residues: [407-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLLPGKENKL SDDGRISEKS GRPSDTSRND SDISIAGKDD IGIIANVDDI TEKESAAAND  60
   61 NDENGKNEAG AKSDFDFADG LLSQEGAHDQ IISSIDTKLL LKKPSSSSEV VLIQHEVAAS 120
  121 SALIETEESK KELAPPFKLS IFVDELNTFE KTLIQDLPLY NGINEERPKK DDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [580-840]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPFIPISKSV VSLDDNGFYK LLERQLIDEE PSISQLSKRR GMFYGNRRNH YLRPPAVPSL  60
   61 RYLQNRTPTI WLSEDDQELV KNINTYGYNW ELISAHMTHR LTYSYLSNIE RRTPWQCFER 120
  121 FVQLNERFNF SDLKGPRAHS AQQWLIEAHK FQQRQNRRIS PLGVNTESIQ RGHRRLRWAS 180
  181 MFEAIRKCMK KRENTPRPNP TQPRKPLDCK NMKVPTPAEM SLLKAQRDEA LRRDIQLRRT 240
  241 VKNRLQQRQQ QSQQAHSSRA Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [841-959]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPIPSNGKSS SNLARNGQAS APRPNQKQYT EQDIIESYSR KLLEQKPDIG PEMALKAAKN  60
   61 YYRTLREQQQ QLKQHQIQQQ RQQLQEESSH VQQLQQLQPG SSSSATEIIS ISIFSFQYF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.624 0.966 histone acetyltransferase complex a.22.1 Histone-fold
View Download 0.462 0.966 histone acetyltransferase complex a.133.1 Phospholipase A2, PLA2
View Download 0.652 0.966 histone acetyltransferase complex f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.506 0.966 histone acetyltransferase complex a.7.7 BAG domain
View Download 0.576 0.966 histone acetyltransferase complex a.19.1 Fertilization protein
View Download 0.458 0.966 histone acetyltransferase complex b.88.1 Mss4-like
View Download 0.451 0.966 histone acetyltransferase complex a.7.8 GAT domain
View Download 0.424 0.966 histone acetyltransferase complex a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.421 0.966 histone acetyltransferase complex a.149.1 RNase III endonuclease catalytic domain
View Download 0.415 0.966 histone acetyltransferase complex a.47.2 t-snare proteins
View Download 0.401 0.966 histone acetyltransferase complex f.18.1 F1F0 ATP synthase subunit A
View Download 0.394 0.966 histone acetyltransferase complex a.22.1 Histone-fold
View Download 0.391 0.966 histone acetyltransferase complex a.24.3 Cytochromes
View Download 0.389 0.966 histone acetyltransferase complex a.24.1 Apolipoprotein
View Download 0.389 0.966 histone acetyltransferase complex a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.380 0.966 histone acetyltransferase complex a.142.1 PTS-regulatory domain, PRD
View Download 0.371 0.966 histone acetyltransferase complex a.22.1 Histone-fold
View Download 0.370 0.966 histone acetyltransferase complex f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.364 0.966 histone acetyltransferase complex a.24.3 Cytochromes
View Download 0.353 0.966 histone acetyltransferase complex a.47.2 t-snare proteins
View Download 0.324 0.966 histone acetyltransferase complex a.7.4 Smac/diablo
View Download 0.310 0.966 histone acetyltransferase complex a.24.14 FAT domain of focal adhesion kinase
View Download 0.309 0.966 histone acetyltransferase complex a.90.1 Transcription factor STAT-4 N-domain
View Download 0.301 0.966 histone acetyltransferase complex a.29.2 Bromodomain
View Download 0.290 0.966 histone acetyltransferase complex a.7.1 Spectrin repeat
View Download 0.261 0.966 histone acetyltransferase complex a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.257 0.966 histone acetyltransferase complex a.24.9 alpha-catenin/vinculin
View Download 0.251 0.966 histone acetyltransferase complex a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.245 0.966 histone acetyltransferase complex a.4.5 "Winged helix" DNA-binding domain
View Download 0.245 0.966 histone acetyltransferase complex f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.244 0.966 histone acetyltransferase complex a.47.2 t-snare proteins
View Download 0.242 0.966 histone acetyltransferase complex a.39.1 EF-hand
View Download 0.239 0.966 histone acetyltransferase complex i.11.1 Computational models partly based on NMR data
View Download 0.238 0.966 histone acetyltransferase complex f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.236 0.966 histone acetyltransferase complex a.87.1 DBL homology domain (DH-domain)
View Download 0.236 0.966 histone acetyltransferase complex b.46.1 FMT C-terminal domain-like
View Download 0.235 0.966 histone acetyltransferase complex a.25.1 Ferritin-like
View Download 0.233 0.966 histone acetyltransferase complex a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.230 0.966 histone acetyltransferase complex a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.228 0.966 histone acetyltransferase complex a.7.1 Spectrin repeat
View Download 0.227 0.966 histone acetyltransferase complex a.22.1 Histone-fold
View Download 0.215 0.966 histone acetyltransferase complex f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.215 0.966 histone acetyltransferase complex f.13.1 Family A G protein-coupled receptor-like
View Download 0.214 0.966 histone acetyltransferase complex a.94.1 Ribosomal protein L19 (L19e)
View Download 0.214 0.966 histone acetyltransferase complex a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.212 0.966 histone acetyltransferase complex d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.212 0.966 histone acetyltransferase complex e.20.1 Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
View Download 0.210 0.966 histone acetyltransferase complex f.13.1 Family A G protein-coupled receptor-like
View Download 0.208 0.966 histone acetyltransferase complex a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.203 0.966 histone acetyltransferase complex f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.203 0.966 histone acetyltransferase complex d.15.6 Superantigen toxins, C-terminal domain
View Download 0.202 0.966 histone acetyltransferase complex f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore


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