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View Structure Prediction Details

Protein: GGA1
Organism: Saccharomyces cerevisiae
Length: 557 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GGA1.

Description E-value Query
Range
Subject
Range
GGA1_YEAST - ADP-ribosylation factor-binding protein GGA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
GGA1 - Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p...
0.0 [1..557] [1..557]
GGA2 - golgi-associated, gamma adaptin ear containing, ARF binding protein 2
0.0 [9..552] [13..601]
gi|12835938 - gi|12835938|dbj|BAB23426.1| unnamed protein product [Mus musculus]
0.0 [9..552] [16..591]
YB0G_SCHPO - Probable ADP-ribosylation factor-binding protein C25H2.16c OS=Schizosaccharomyces pombe (strain 972 ...
SPBC25H2.16c - adaptin
0.0 [15..554] [1..530]
gi|25404261, gi|... - gi|4249386|gb|AAD14483.1|AAD14483 Strong similarity to gb|AF061286 gamma-adaptin 1 from Arabidopsis ...
0.0 [60..551] [332..859]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQRIELTSE PVRKPRSTES SLLRKIQRAC RSTLPEPDLG LNLDVADYIN SKQGATPREA  60
   61 VLAIEKLVNN GDTQAAVFAL SLLDVLVKNC GYS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 171.134302
Match: 1dvpA_
Description: Hrs
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [94-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHLQISRKEF LNDLVKRFPE QPPLRYSKVQ QMILEAIEEW YQTICKHASY KDDLQYINDM  60
   61 HKLLKYKGYT FPKVGSENLA VLRPNDQLRT PSEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 171.134302
Match: 1dvpA_
Description: Hrs
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.93554535044651 bayes_pls_golite062009
transporter activity 1.4237388137024 bayes_pls_golite062009
protein binding 1.17960228368657 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [188-234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEEQERAQAA KLEELLRSGK PDDLKEANKL MKIMAGFKDD TKVAVKQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [283-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLIEEERDDD ALVSNLSKFN DLVIQLLKRY KSIKGMKEEE LNVPDTNEPA KELNLIDFDD  60
   61 DTTANTPSVT SPSKSLQPFD DLLGDFNKVS LSSPKSPQEN DTVVDILGDA HSKSSGIDLL 120
  121 DFDSQPG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.52
Match: 1vsgA
Description: Variant surface glycoprotein (N-terminal domain)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [235-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AINNELNKLK RKADLFNEML TSADEPDLEN EAIQELYGDL KSAQPKFK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.52
Match: 1vsgA
Description: Variant surface glycoprotein (N-terminal domain)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [410-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESKTALSAYS NSIVLPNGLL NSSSNSKEIT AQSQRHILNQ SDHLRIDYEL TRESMTKLRL  60
   61 VIFYSNISSD PITNFALLVA SPKGTTLSLQ PQSGNMLQSN SRDGIKQIAS VEGISVNLGK 120
  121 PIKLKWKANY CTKGDSKEES GTTSLPTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.39794
Match: 1iu1A_
Description: Gamma1-adaptin domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle