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View Structure Prediction Details

Protein: HXT3
Organism: Saccharomyces cerevisiae
Length: 567 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXT3.

Description E-value Query
Range		 Subject
Range
HXT3 - Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low ...
gi|190404717 - gi|190404717|gb|EDV07984.1| low affinity glucose transporter [Saccharomyces cerevisiae RM11-1a]
HXT3_YEAST - Low-affinity glucose transporter HXT3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HX...
gi|151942319 - gi|151942319|gb|EDN60675.1| hexose transporter [Saccharomyces cerevisiae YJM789]
 0.0 [1..567] [1..567]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
 0.0 [22..563] [18..565]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [11..567] [9..570]

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Predicted Domain #1
Region A:
Residues: [1-254] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSTPDLISP QKSSENSNAD LPSNSSQVMN MPEEKGVQDD FQAEADQVLT NPNTGKGAYV  60
   61 TVSICCVMVA FGGFVFGWDT GTISGFVAQT DFLRRFGMKH KDGSYYLSKV RTGLIVSIFN 120
  121 IGCAIGGIIL AKLGDMYGRK MGLIVVVVIY IIGIIIQIAS INKWYQYFIG RIISGLGVGG 180
  181 IAVLSPMLIS EVAPKEMRGT LVSCYQLMIT LGIFLGYCTN FGTKNYSNSV QWRVPLGLCF 240
  241 AWALFMIGGM TFVP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [303-514] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGSASWGELF TGKPAMFKRT MMGIMIQSLQ QLTGDNYFFY YGTTVFNAVG MSDSFETSIV  60
   61 FGVVNFFSTC CSLYTVDRFG RRNCLLYGAI GMVCCYVVYA SVGVTRLWPN GEGNGSSKGA 120
  121 GNCMIVFACF YIFCFATTWA PIAYVVISET FPLRVKSKAM SIATAANWLW GFLIGFFTPF 180
  181 ITGAINFYYG YVFMGCMVFA YFYVFFFVPE TK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 472.218487
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.74077413704789 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 2.63293544825311 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [255-302] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPRYLVEAG QIDEARASLS KVNKVAPDHP FIQQELEVIE ASVEEARA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [515-567] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLTLEEVNDM YAEGVLPWKS ASWVPTSQRG ANYDADALMH DDQPFYKKMF GKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 472.218487
Match: 1ja5A_
Description: No description for 1ja5A_ was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle