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View Structure Prediction Details

Protein: MSN5
Organism: Saccharomyces cerevisiae
Length: 1224 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSN5.

Description E-value Query
Range
Subject
Range
XPO5 - exportin 5
0.0 [1..1137] [3..1126]
MSN5_YEAST - Protein MSN5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSN5 PE=1 SV=1
MSN5 - Karyopherin involved in nuclear import and export of proteins, including import of replication prote...
0.0 [1..1224] [1..1224]
XPO5_MOUSE - Exportin-5 OS=Mus musculus GN=Xpo5 PE=1 SV=1
0.0 [1..1137] [3..1126]
gi|12407463 - gi|12407463|gb|AAG53520.1|AF222746_1 RanBP21 [Drosophila melanogaster]
0.0 [3..1130] [8..1150]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [457..1137] [2..677]

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Predicted Domain #1
Region A:
Residues: [1-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSTGASQIV SALDVIYSPK SNNSQRQEAQ KFLDEVKLCS ESPFWGYEIA LQNPTNSILK  60
   61 YFGLGLLDHA VKKNWNDYDE GKRVALRKWV MELNFGVQDY DTRYIKEKLA TLWVEVAKRT 120
  121 WGEALKQTNP TEEQLLTSWV DMDNNLFELW NINQSSRELA LIIFRILFED VFLLDDLIVL 180
  181 KRMTVIQPLC VMIVCPIEVF AIKYKFSDKW TKFKANEEGW FSVWIPELNN ALQQNNSEYI 240
  241 IRLLETLKTC LNW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1ibrB_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [254-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLTEVIVRND VLSSLLTCLS SNIPRAQSMA LDSIHILLTR PYSNESHYQM TIDRVFDNMD  60
   61 LLDSVYESLL FDPTDDIDET KYPIIKKFVD MISCLYVCVP KIKETNGQIQ KYFKLVLKTT 120
  121 YNPSLIVSGL TLDLWCTCLR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [394-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDEYLPKLEK YVIPDLLQFA ADALVYYEQI DGHISKKFAE IDFQSKSEFQ TFCSTYRKRI  60
   61 RDIIRLISCV ELDLTYDWLN NRLNNYFS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.897 N/A N/A a.46.1 Methionine synthase domain

Predicted Domain #4
Region A:
Residues: [482-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPFGQQVLSS TFLDHKLEPY LGALSQYMIV ECFINGCIRW KIWYPTGDDY DEKLDSILQK  60
   61 LEILSNQLIA LNLREPLLLK KQIQNFALFL TMLKDNVLFT LLEKIITSAT MDYPEINLEE 120
  121 RGAESDAVRD LRYACGIELN RMALLMPESL KKIYPDLESV IARIMP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.862 N/A N/A a.7.7 BAG domain

Predicted Domain #5
Region A:
Residues: [648-1131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLSYHEKISF KSFLLIIVLK SSLDMKEERF AAIVDPELLA WSDKTTVVGL SDLHWFMERL  60
   61 GIVQIAEYFQ RRDIDENSDL LSIPIDDEGK ELKSELTKRW QSLFPVRATR MFIHYSMQSI 120
  121 KTDEEFKMLQ DLWRPRIVPI LPYITRLLYQ LQSYHDPDNW KGLPTVVQSF VKYSTIERFW 180
  181 EAGASNKSKD EFIDEHMKAM QTLRDFADSV GHIIRYTREY TLLVLSAISS LGSVFYLLDE 240
  241 SPDLLLNSIA IFKPGSNEIS PGVSTHGWKH IMNIAIRPIL KGCPKDCLGK FMPAFLPKLF 300
  301 EILDLLLCQK WSSHMNDMDM NPVPTDDDQM TEEILEENLL RQLTTVVVRI VIDCVGQGNA 360
  361 NPNSAKSRLN NHQMEMRKII FNDLNTLAPF LKLLNHLISF KDTKCSFNSI LVMKCCLTSV 420
  421 LNQNNTVDEY FTFEVMKNLL LNVLCNSAFK DSFHEALYAF TVIFLTLCKE YPSARAFLFE 480
  481 ISNG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1132-1224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNIDELYRNL RSVDEYKTQR ALMIDFIDWV KSTSGKEDGN VDHAGDERKR QEKREAILKK  60
   61 ANERLIKKNK ENGDMLDDPN IEDGAVGNLF DDN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [906-968]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISPGVSTHGW KHIMNIAIRP ILKGCPKDCL GKFMPAFLPK LFEILDLLLC QKWSSHMNDM  60
   61 DMN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [969-1147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVPTDDDQMT EEILEENLLR QLTTVVVRIV IDCVGQGNAN PNSAKSRLNN HQMEMRKIIF  60
   61 NDLNTLAPFL KLLNHLISFK DTKCSFNSIL VMKCCLTSVL NQNNTVDEYF TFEVMKNLLL 120
  121 NVLCNSAFKD SFHEALYAFT VIFLTLCKEY PSARAFLFEI SNGYNIDELY RNLRSVDEY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1148-1224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTQRALMIDF IDWVKSTSGK EDGNVDHAGD ERKRQEKREA ILKKANERLI KKNKENGDML  60
   61 DDPNIEDGAV GNLFDDN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle