YRC Public Data Repository - Protein Structure Prediction

Protein:	PRO1
Organism:	Saccharomyces cerevisiae
Length:	428 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRO1.

Description	E-value	Query Range	Subject Range
gi\|172241 - gi\|172241\|gb\|AAA34904.1\| glutamyl kinase [Saccharomyces cerevisiae]	0.0	[1..428]	[1..428]
PROB_SALTI - Glutamate 5-kinase OS=Salmonella typhi GN=proB PE=3 SV=1 PROB_SALTY - Glutamate 5-kinase OS=Salmonella typhimurium GN=proB PE=3 SV=1 gi\|29138543, gi\|... - gi\|29142911\|ref\|NP_806253.1\| gamma-glutamyl kinase [Salmonella enterica subsp. enterica serovar Typh... gi\|16759316 - gi\|16759316\|ref\|NP_454933.1\| gamma-glutamyl kinase [Salmonella enterica subsp. enterica serovar Typh... PROB_SALTI - Glutamate 5-kinase OS=Salmonella typhi GN=proB PE=3 SV=1 PROB_SALTY - Glutamate 5-kinase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=proB PE=3 SV=1 gi\|194459207, gi... - gi\|194472843\|ref\|ZP_03078827.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Kent... PROB_SALSV - Glutamate 5-kinase OS=Salmonella schwarzengrund (strain CVM19633) GN=proB PE=3 SV=1 PROB_SALA4 - Glutamate 5-kinase OS=Salmonella agona (strain SL483) GN=proB PE=3 SV=1 gi\|197242902, gi... - gi\|197264647\|ref\|ZP_03164721.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Sain... gi\|195631747, gi... - gi\|195631747\|gb\|EDX50267.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Newport ... gi\|168819086, gi... - gi\|205344243\|gb\|EDZ31007.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Weltevre... PROB_SALNS - Glutamate 5-kinase OS=Salmonella newport (strain SL254) GN=proB PE=3 SV=1 lcl\|NC_016856.1_... - [gene=proB] [protein=gamma-glutamyl kinase] [protein_id=YP_005235996.1] [location=367000..368103] PROB_SALCH - Glutamate 5-kinase OS=Salmonella choleraesuis GN=proB PE=3 SV=1 PROB_SALCH - Glutamate 5-kinase OS=Salmonella choleraesuis (strain SC-B67) GN=proB PE=3 SV=1 PROB_SALHS - Glutamate 5-kinase OS=Salmonella heidelberg (strain SL476) GN=proB PE=3 SV=1 gi\|205333449, gi... - gi\|205333449\|gb\|EDZ20213.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Kentucky... PROB_SALCH - Glutamate 5-kinase OS=Salmonella choleraesuis GN=proB PE=3 SV=1 gi\|168238571, gi... - gi\|197288580\|gb\|EDY27957.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Schwarze... PROB_SALTY - Glutamate 5-kinase OS=Salmonella typhimurium GN=proB PE=3 SV=1 gi\|168240062, gi... - gi\|205340361\|gb\|EDZ27125.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Heidelbe... gi\|168261262, gi... - gi\|205349871\|gb\|EDZ36502.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Hadar st... gi\|167553091, gi... - gi\|205322380\|gb\|EDZ10219.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Saintpau... gi\|205328602, gi... - gi\|205328602\|gb\|EDZ15366.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar 4,[5],12... PROB_SALEP - Glutamate 5-kinase OS=Salmonella enteritidis PT4 (strain P125109) GN=proB PE=3 SV=1 gi\|213161395 - gi\|213161395\|ref\|ZP_03347105.1\| gamma-glutamyl kinase [Salmonella enterica subsp. enterica serovar T... gi\|213425148 - gi\|213425148\|ref\|ZP_03357898.1\| gamma-glutamyl kinase [Salmonella enterica subsp. enterica serovar T... gi\|213852531 - gi\|213852531\|ref\|ZP_03382063.1\| gamma-glutamyl kinase [Salmonella enterica subsp. enterica serovar T... PROB_SALDC - Glutamate 5-kinase OS=Salmonella dublin (strain CT_02021853) GN=proB PE=3 SV=1 gi\|199603312, gi... - gi\|200390867\|ref\|ZP_03217478.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Virc... gi\|204926876, gi... - gi\|204926876\|ref\|ZP_03218078.1\| glutamate 5-kinase [Salmonella enterica subsp. enterica serovar Javi... gi\|238913289 - gi\|238913289\|ref\|ZP_04657126.1\| gamma-glutamyl kinase [Salmonella enterica subsp. enterica serovar T... PROB_SALG2 - Glutamate 5-kinase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=proB PE=3 SV=1	6.0E-81	[10..423]	[5..364]
PROB_SERMA - Glutamate 5-kinase OS=Serratia marcescens GN=proB PE=3 SV=1	2.0E-80	[10..423]	[5..364]
EG10768 - gamma-glutamate kinase / Glutamate 5-kinase, proline biosynthesis; dimeric; feedback inhibition by p... PROB_ECOLC - Glutamate 5-kinase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=proB PE=3 SV=1 gi\|15829523, gi\|... - gi\|15829523\|ref\|NP_308296.1\| gamma-glutamyl kinase [Escherichia coli O157:H7 str. Sakai], gi\|1335972... PROB_ECOL5 - Glutamate 5-kinase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=proB PE=3 SV=1 PROB_SHIF8 - Glutamate 5-kinase OS=Shigella flexneri serotype 5b (strain 8401) GN=proB PE=3 SV=1 PROB_ECOL6 - Glutamate 5-kinase OS=Escherichia coli O6 GN=proB PE=3 SV=1 gi\|208818393, gi... - gi\|208818393\|ref\|ZP_03258713.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4042], gi\|208738... gi\|208814371, gi... - gi\|208814371\|ref\|ZP_03255700.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4045], gi\|208735... PROB_ECOSE - Glutamate 5-kinase OS=Escherichia coli (strain SE11) GN=proB PE=3 SV=1 PROB_ECO5E - Glutamate 5-kinase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=proB PE=3 SV=1 gi\|217321799, gi... - gi\|217325578\|ref\|ZP_03441662.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. TW14588], gi\|21732... PROB_ECO27 - Glutamate 5-kinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=proB PE=3 SV=1 EG10768 - gamma-glutamate kinase / Glutamate 5-kinase, proline biosynthesis; dimeric; feedback inhibition by p... PROB_ECOK1 - Glutamate 5-kinase OS=Escherichia coli O1:K1 / APEC GN=proB PE=3 SV=1 PROB_ECO45 - Glutamate 5-kinase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=proB PE=3 SV=1 PROB_ECO57 - Glutamate 5-kinase OS=Escherichia coli O157:H7 GN=proB PE=3 SV=1 gi\|124501704, gi... - gi\|124526648\|ref\|ZP_01698557.1\| glutamate 5-kinase [Escherichia coli B], gi\|124501704\|gb\|EAY49166.1\|... PROB_ECO8A - Glutamate 5-kinase OS=Escherichia coli O8 (strain IAI1) GN=proB PE=3 SV=1 PROB_ECOUT - Glutamate 5-kinase OS=Escherichia coli (strain UTI89 / UPEC) GN=proB PE=3 SV=2 gi\|188999644, gi... - gi\|188999644\|gb\|EDU68630.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4076], gi\|168783003\|... gi\|15799947, gi\|... - gi\|15799947\|ref\|NP_285959.1\| gamma-glutamyl kinase [Escherichia coli O157:H7 EDL933], gi\|12513016\|gb... gi\|168776117, gi... - gi\|187768425\|gb\|EDU32269.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4196], gi\|168776117\|... gi\|189377327, gi... - gi\|189377327\|gb\|EDU95743.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC508], gi\|168800319\|r... gi\|189370716, gi... - gi\|189370716\|gb\|EDU89132.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC869], gi\|168789715\|r... PROB_ECOSM - Glutamate 5-kinase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=proB PE=3 SV=1 PROB_ECODH - Glutamate 5-kinase OS=Escherichia coli (strain K12 / DH10B) GN=proB PE=3 SV=1 gi\|208728806, gi... - gi\|208809005\|ref\|ZP_03251342.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4206], gi\|208728... gi\|195938645 - gi\|195938645\|ref\|ZP_03084027.1\| gamma-glutamyl kinase [Escherichia coli O157:H7 str. EC4024] gi\|75258755 - gi\|75258755\|ref\|ZP_00730145.1\| COG0263: Glutamate 5-kinase [Escherichia coli E22] gi\|188493000, gi... - gi\|75513572\|ref\|ZP_00735963.1\| COG0263: Glutamate 5-kinase [Escherichia coli 53638], gi\|188493000\|re... gi\|192958093, gi... - gi\|75237300\|ref\|ZP_00721347.1\| COG0263: Glutamate 5-kinase [Escherichia coli E110019], gi\|193068730\|... gi\|75241686, gi\|... - gi\|75241686\|ref\|ZP_00725523.1\| COG0263: Glutamate 5-kinase [Escherichia coli F11], gi\|191171439\|ref\|... sp\|B7UJD0\|PROB_ECO27 - Glutamate 5-kinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=proB PE=3 SV=1 PROB_SHIBS - Glutamate 5-kinase OS=Shigella boydii serotype 4 (strain Sb227) GN=proB PE=3 SV=1 gi\|89107115, gi\|... - gi\|89107115\|ref\|AP_000895.1\| gamma-glutamate kinase [Escherichia coli str. K-12 substr. W3110], gi\|8... PROB_SHISS - Glutamate 5-kinase OS=Shigella sonnei (strain Ss046) GN=proB PE=3 SV=1 PROB_SHIDS - Glutamate 5-kinase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=proB PE=3 SV=1 gi\|194438223, gi... - gi\|83586318\|ref\|ZP_00924953.1\| COG0263: Glutamate 5-kinase [Escherichia coli 101-1], gi\|194438223\|re... PROB_ECO55 - Glutamate 5-kinase OS=Escherichia coli (strain 55989 / EAEC) GN=proB PE=3 SV=1 PROB_SHIB3 - Glutamate 5-kinase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=proB PE=3 SV=1 PROB_ECO81 - Glutamate 5-kinase OS=Escherichia coli O81 (strain ED1a) GN=proB PE=3 SV=1 PROB_ECOLU - Glutamate 5-kinase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=proB PE=3 SV=1 gi\|194432626, gi... - gi\|83570390\|ref\|ZP_00921835.1\| COG0263: Glutamate 5-kinase [Shigella dysenteriae 1012], gi\|194432626... PROB_ECO7I - Glutamate 5-kinase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=proB PE=3 SV=1 gi\|194414335, gi... - gi\|75211187\|ref\|ZP_00711294.1\| COG0263: Glutamate 5-kinase [Escherichia coli B171], gi\|194427565\|ref... gi\|75231158, gi\|... - gi\|75231158\|ref\|ZP_00717580.1\| COG0263: Glutamate 5-kinase [Escherichia coli B7A], gi\|191165764\|ref\|... PROB_ECO24 - Glutamate 5-kinase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=proB PE=3 SV=1 PROB_ECOHS - Glutamate 5-kinase OS=Escherichia coli O9:H4 (strain HS) GN=proB PE=3 SV=1 gi\|227838343, gi... - gi\|227884742\|ref\|ZP_04002547.1\| glutamate 5-kinase [Escherichia coli 83972], gi\|227838343\|gb\|EEJ4880... PROB_ECOLI - Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK) - Escherichia coli gi\|237707739, gi... - gi\|237707739\|ref\|ZP_04538220.1\| glutamate 5-kinase [Escherichia sp. 3_2_53FAA], gi\|226898949\|gb\|EEH8... PROB_ECOBW - Glutamate 5-kinase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=proB PE=3 SV=1 gi\|242376074, gi... - gi\|251783801\|ref\|YP_002998105.1\| hypothetical protein B21_00242 [Escherichia coli BL21], gi\|24237607... gi\|253325775, gi... - gi\|254287161\|ref\|YP_003052909.1\| gamma-glutamyl kinase [Escherichia coli BL21(DE3)], gi\|253976468\|gb... gi\|254160358, gi... - gi\|254160358\|ref\|YP_003043466.1\| gamma-glutamyl kinase [Escherichia coli B str. REL606], gi\|25397225... gi\|254791402, gi... - gi\|254791402\|ref\|YP_003076239.1\| gamma-glutamate kinase [Escherichia coli O157:H7 str. TW14359], gi\|... PROB_ECOL6 - Glutamate 5-kinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=proB PE=3 SV=1 gi\|168757270, gi... - gi\|189355741\|gb\|EDU74160.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4401], gi\|168757270\|... gi\|168750226, gi... - gi\|188015601\|gb\|EDU53723.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4113], gi\|168750226\|... gi\|168770040, gi... - gi\|189361093\|gb\|EDU79512.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4486], gi\|168770040\|... gi\|189366368, gi... - gi\|189366368\|gb\|EDU84784.1\| glutamate 5-kinase [Escherichia coli O157:H7 str. EC4501], gi\|168763483\|...	2.0E-80	[10..423]	[5..364]
gi\|4902977, gi\|42497 - dbj\|BAA77911.1\| Glutamate 5-kinase (EC 2.7.2.11). [Escherichia coli], gi\|42497\|emb\|CAA25363.1\| unnam...	8.0E-80	[10..423]	[5..364]
PROB_SYNY3 - Glutamate 5-kinase OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=proB PE=3 SV=1 gi\|7434577 - pir\|\|S75182 glutamate 5-kinase (EC 2.7.2.11) - Synechocystis sp. (strain PCC 6803) PROB_SYNY3 - Glutamate 5-kinase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=proB PE=3 SV=1	4.0E-79	[1..423]	[1..370]
PROB_SCHPO - Probable glutamate 5-kinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC17H9.13c P... SPAC17H9.13c - glutamate 5-kinase	4.0E-79	[2..423]	[4..384]

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Predicted Domain #1

Region A:
Residues: [1-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDANESKSY TIVIKLGSSS LVDEKTKEPK LAIMSLIVET VVKLRRMGHK VIIVSSGGIA  60
   61 VGLRTMRMNK RPKHLAEVQA IAAIGQGRLI GRWDLLFSQF DQRIAQILLT RNDILDWTQY 120
  121 KNAQNTINEL LNMGVIPIVN ENDTLSVREI KFGDNDTLSA ITSALIHADY LFLLTDVDCL 180
  181 YTDNPRTNPD AMPILVVPDL SKGLPGVNTA GGSGSDVGTG GMETKLVAAD LATNAGVHTL 240
  241 IMKSDTPANI GRIVEYMQTL ELDDENKVKQ AYNGDLTDLQ KREFEKLKAL NV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.045757
Match:	1e19A_
Description:	Carbamate kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [293-428]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLHTKFIAND NKHHLKNREF WILHGLVSKG AVVIDQGAYA ALTRKNKAGL LPAGVIDVQG  60
   61 TFHELECVDI KVGKKLPDGT LDPDFPLQTV GKARCNYTSS ELTKIKGLHS DQIEEELGYN 120
  121 DSEYVAHREN LAFPPR

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	22.200659
Match:	PF01472
Description:	PUA domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits