YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RKM4
Organism: Saccharomyces cerevisiae
Length: 494 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RKM4.

Description E-value Query
Range
Subject
Range
RKM4 - Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 55); ...
RKM4_YEAST - Ribosomal lysine N-methyltransferase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=R...
gi|190404795 - gi|190404795|gb|EDV08062.1| hypothetical protein SCRG_00269 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..494] [1..494]
gi|8570443, gi|2... - gi|8570443|gb|AAF76470.1|AC020622_4 Contains similarity to a hypothetical protein gi|6983878 from Or...
3.0E-88 [3..451] [5..412]
RBCMT_PEA - Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic OS=...
3.0E-84 [4..405] [50..404]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-76 [3..405] [51..406]
RBCMT_TOBAC - Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic OS=...
8.0E-75 [5..405] [54..407]
SETD4 - SET domain containing 4
8.0E-64 [13..326] [38..329]

Back

Predicted Domain #1
Region A:
Residues: [1-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDFSRDTEN FVCWLKTTAE IEVSPKIEIK DLCCDNQGRA VVATQKIKKD ETLFKIPRSS  60
   61 VLSVTTSQLI KDYPSLKDKF LNETGSWEGL IICILYEMEV LQERSRWAPY FKVWNKPSDM 120
  121 NALIFWDDNE LQLLKPSLVL ERIGKKEAKE MHERIIKSIK QIGGEFSRVA TSFEFDNFAY 180
  181 IASIILSYSF DLEMQDSSVN ENEEEETSEE ELENERYLKS MIPLADMLNA DTSKCNANLT 240
  241 YDSNCLKMVA LRDIEKNEQV YNIYGEHPNS ELLRRYGYVE W

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
histone methyltransferase activity 6.20878333364554 bayes_pls_golite062009
protein methyltransferase activity 6.08778683840554 bayes_pls_golite062009
lysine N-methyltransferase activity 5.45106430536252 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 5.45106430536252 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 5.45106430536252 bayes_pls_golite062009
N-methyltransferase activity 3.98411678860954 bayes_pls_golite062009
histone methyltransferase activity (H3-K9 specific) 3.54138873512018 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 2.69428385009711 bayes_pls_golite062009
methyltransferase activity 2.33114816345072 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 2.25175257044903 bayes_pls_golite062009
binding 1.67469558504376 bayes_pls_golite062009
nucleic acid binding 1.29511015534184 bayes_pls_golite062009
protein binding 1.07532079834012 bayes_pls_golite062009
transferase activity 0.653108419761009 bayes_pls_golite062009
chromatin binding 0.628375771647179 bayes_pls_golite062009
catalytic activity 0.414641636618101 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [282-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSKYDFGEV LLENIVEALK ETFETNTEFL DRCIDILRNN ANIQEFLEGE EIVLDSYDCY  60
   61 NNGELLPQLI LLVQILTILC QIPGLCKLDI KAMERQVERI VKKCLQLIEG ARATTNCSAT 120
  121 WKRCIMKRLA DYPIKKCVSI EKPSKGNSLT REELRDVMAR RVLKSEIDSL QVCEETIDKN 180
  181 YKVIPDEKLL TNILKRKLTE EEKSSVKRPC VKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle