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View Structure Prediction Details

Protein: VHS1
Organism: Saccharomyces cerevisiae
Length: 461 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VHS1.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [47..458] [140..524]
gi|18175903 - gi|18175903|gb|AAL59948.1| putative calcium-dependent protein kinase [Arabidopsis thaliana]
0.0 [48..459] [61..445]
gi|19171502 - gi|19171502|emb|CAC87494.1| calcium-dependent protein kinase [Solanum lycopersicum]
0.0 [46..459] [91..476]
gi|5162882, gi|5... - gi|5162882|dbj|BAA81751.1| calcium-dependent protein kinase [Marchantia polymorpha], gi|5162878|dbj|...
0.0 [48..458] [69..452]
gi|15289758 - gi|15289758|dbj|BAB63463.1| calcium dependent protein kinase [Solanum tuberosum]
0.0 [43..458] [97..485]
gi|16215471 - gi|16215471|emb|CAC82999.1| calcium-dependent protein kinase 3 [Nicotiana tabacum]
0.0 [43..458] [97..485]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMMFHNCRIN NYLITSQIGE GAYGLVYRAL DIRTDRQYAI KAVVQSYGVS KEADMGNDKI  60
   61 HKNSVKLQKK LAKLFKESKN VVRVPSIDLE SIENMSEEDF KKLPHYKEIS 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [124-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHEVLQSAVC TFIVMDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 195.512579
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [111-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHLRVHHHKN IVT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [141-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPTDLFTSIV DNRHFVTNGL LVKKVFLQIC SALNYCHEHG IYHCDIKPEN LLLDTEDNVF  60
   61 LCDFGLST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 195.512579
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [209-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSTYIKPNVC IGSSYYMPPE RISFDGRVSS SKSGGHKLGK VCPSCNGDLW SLGIILINLT  60
   61 CIRNPWLKAD KTEDNTYYYF TKDPNILKQI LPLSDDFYSL LSKILQVNPK NRMSLQELMK 120
  121 EVSSITSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 195.512579
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [337-461]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNEGPLSKVP PLSKSVYEKF VSPVDNTNEN LSPKSYVYMH DSKAAKNLSY TSSSEEEDGI  60
   61 KEGIDDDNGS RSGSFGTLDT DTGLHSSFTS TSCESDNECS KISNKFSLFE KKFNELRMSS 120
  121 SSLTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 1dtlA_
Description: Troponin C
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle