YRC Public Data Repository - Protein Structure Prediction

Protein:	COQ4
Organism:	Saccharomyces cerevisiae
Length:	335 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ4.

Description	E-value	Query Range	Subject Range
COQ4 - Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization o... COQ4_YEAST - Ubiquinone biosynthesis protein COQ4, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 ...	0.0	[1..335]	[1..335]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[4..335]	[1..332]
COQ4_SCHPO - Ubiquinone biosynthesis protein coq4, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC ... coq4 - ubiquinone biosynthesis protein Coq4	1.0E-93	[70..307]	[33..271]
gi\|4929653, gi\|7... - gi\|7705807\|ref\|NP_057119.1\| coenzyme Q4 homolog [Homo sapiens], gi\|4929653\|gb\|AAD34087.1\|AF151850_1 ...	8.0E-86	[68..305]	[24..258]
COQ4_ARATH - Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Arabidopsis thaliana GN=At2g03690 PE=...	1.0E-80	[88..305]	[8..222]
gi\|17230306, gi\|... - gi\|17230306\|ref\|NP_486854.1\| hypothetical protein alr2814 [Nostoc sp. PCC 7120], gi\|17131908\|dbj\|BAB... gi\|25381611 - pir\|\|AG2157 hypothetical protein alr2814 [imported] - Nostoc sp. (strain PCC 7120)	3.0E-65	[76..303]	[5..230]

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Predicted Domain #1

Region A:
Residues: [1-79]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLSLLRST ATLPVKCQRR GLILPAAAMY TLGSLIFGKE ARLADAMERG ELHNKNVDYA  60
   61 KEAEERTELR IRALANTRP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [80-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPRYNGHVP LHRYEKLLLF AISGWNSFFH PEDGYNIVQL GEATALPVFL ENLKQTMLSD  60
   61 SSGRRILKEQ PNITTEILHM DKLAKLPHNT FGYVYYQWLK RENVSPDTRA PVKFIDDPMH 120
  121 AYIFKRYRQC HDFYHAITNM PIIIEGEITI KALEGANLGV PMAILGGILA PLRLKKVQRK 180
  181 RLYNIYLPWA VRTGLSCKPL INVYWEEMLE KDVTALRKEL KITLPPDLRT MRKERAALRK 240
  241 EIDAKYNSQK RATTPA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [219-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIIIEGEIT IKALEGANLG VPMAILGGIL APLRLKKVQR KRLYNIYLPW AVRTGLSCKP  60
   61 LINVYWEEML EKDVTALRKE LKITLPPDLR TMRKERAALR KEIDAKYNSQ KRATTPA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits