YRC Public Data Repository - Protein Structure Prediction

Protein:	SSY1
Organism:	Saccharomyces cerevisiae
Length:	852 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSY1.

Description	E-value	Query Range	Subject Range
gi\|190404886 - gi\|190404886\|gb\|EDV08153.1\| hypothetical protein SCRG_00363 [Saccharomyces cerevisiae RM11-1a] SSY1 - Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses exte... SSY1_YEAST - SPS-sensor component SSY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSY1 PE=1 SV=1	0.0	[1..852]	[1..852]
gi\|68470470, gi\|... - gi\|68470731\|ref\|XP_720611.1\| N-acetylglucosamine-inducible general amino acid permease [Candida albi... gi\|18568390 - gi\|18568390\|gb\|AAL76065.1\| Gap1 protein [Candida albicans] gi\|238882678 - gi\|238882678\|gb\|EEQ46316.1\| general amino-acid permease GAP1 [Candida albicans WO-1]	0.0	[200..851]	[3..582]
YI26_SCHPO - Uncharacterized amino-acid permease P7G5.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... SPAP7G5.06 - amino acid permease, unknown 4	0.0	[208..834]	[1..567]
gi\|165936285, gi... - gi\|89104688\|ref\|ZP_01177224.1\| COG0833: Amino acid transporters [Yersinia pestis biovar Orientalis s... gi\|108807022, gi... - gi\|108807022\|ref\|YP_650938.1\| lysine transporter [Yersinia pestis Antiqua], gi\|108778935\|gb\|ABG12993... gi\|229679023, gi... - gi\|229903253\|ref\|ZP_04518366.1\| lysine transporter [Yersinia pestis Nepal516], gi\|229679023\|gb\|EEO75... Q66CR2\|Q66CR2_YERPS - Lysine-specific permease lysP, APC family precursor - Yersinia pseudotuberculosis gi\|166009838, gi... - gi\|166009838\|ref\|ZP_02230736.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. E... gi\|165924474, gi... - gi\|165924474\|ref\|ZP_02220306.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|167400403, gi... - gi\|167400403\|ref\|ZP_02305916.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. U... gi\|166211768, gi... - gi\|166211768\|ref\|ZP_02237803.1\| lysine-specific permease LysP [Yersinia pestis biovar Antiqua str. B... gi\|167424094, gi... - gi\|167424094\|ref\|ZP_02315847.1\| lysine-specific permease LysP [Yersinia pestis biovar Mediaevalis st... gi\|167419868, gi... - gi\|167419868\|ref\|ZP_02311621.1\| lysine-specific permease LysP [Yersinia pestis biovar Orientalis str... gi\|186894753, gi... - gi\|186894753\|ref\|YP_001871865.1\| lysine transporter [Yersinia pseudotuberculosis PB1/+], gi\|18669777... gi\|170024977, gi... - gi\|170024977\|ref\|YP_001721482.1\| lysine transporter [Yersinia pseudotuberculosis YPIII], gi\|16975151... gi\|229841266, gi... - gi\|229841266\|ref\|ZP_04461425.1\| lysine transporter [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229843369, gi... - gi\|229843369\|ref\|ZP_04463515.1\| lysine transporter [Yersinia pestis biovar Orientalis str. India 195... gi\|229895742, gi... - gi\|229895742\|ref\|ZP_04510912.1\| lysine transporter [Yersinia pestis Pestoides A], gi\|229700665\|gb\|EE... gi\|149366712, gi... - gi\|149366712\|ref\|ZP_01888746.1\| putative lysine-specific permease [Yersinia pestis CA88-4125], gi\|14... gi\|145599660, gi... - gi\|145599660\|ref\|YP_001163736.1\| lysine transporter [Yersinia pestis Pestoides F], gi\|145211356\|gb\|A... gi\|25296480 - pir\|\|AH0159 probable lysine-specific permease lysP [imported] - Yersinia pestis (strain CO92) gi\|45435969, gi\|... - gi\|45441110\|ref\|NP_992649.1\| lysine transporter [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22126753, gi\|... - gi\|22126753\|ref\|NP_670176.1\| lysine transporter [Yersinia pestis KIM], gi\|21959776\|gb\|AAM86427.1\|AE0... gi\|218928459, gi... - gi\|218928459\|ref\|YP_002346334.1\| lysine transporter [Yersinia pestis CO92], gi\|16121591\|ref\|NP_40490... gi\|51595681, gi\|... - gi\|51595681\|ref\|YP_069872.1\| lysine transporter [Yersinia pseudotuberculosis IP 32953], gi\|51588963\|... gi\|162353225, gi... - gi\|77634357\|ref\|ZP_00796459.1\| COG0833: Amino acid transporters [Yersinia pestis Angola], gi\|1624204... gi\|153948146, gi... - gi\|77632298\|ref\|ZP_00794884.1\| COG0833: Amino acid transporters [Yersinia pseudotuberculosis IP 3175...	0.0	[265..828]	[5..497]
gi\|15485608 - gi\|15485608\|emb\|CAC67419.1\| amino acid transporter [Uromyces viciae-fabae]	0.0	[257..838]	[22..539]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSVNQIYDL FPNKHNIQFT DSHSQEHDTS SSLAKNDTDG TISIPGSIDT GILKSIIEEQ  60
   61 GWNDAELYRS SIQNQRFFLT DKYTKKKHLT MEDMLSPEEE QIYQEPIQDF QTYNKRVQRE 120
  121 YELRERMEEF FRQNTKNDLH ILNEDSLNQQ YSPLGPADYV LPLDRYSRMK HIASNFFRKK 180
  181 LGIPRKLKRR SHYNPNAEGH TKGNSSILSS TTDVIDNASY RNIAIDENVD I

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [232-852]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THKEHAIDEI NEQGASGSES VVEGGSLLHD IEKVFNRSRA TRKYHIQRKL KVRHIQMLSI  60
   61 GACFSVGLFL TSGKAFSIAG PFGTLLGFGL TGSIILATML SFTELSTLIP VSSGFSGLAS 120
  121 RFVEDAFGFA LGWTYWISCM LALPAQVSSS TFYLSYYNNV NISKGVTAGF ITLFSAFSIV 180
  181 VNLLDVSIMG EIVYVAGISK VIIAILMVFT MIILNAGHGN DIHEGVGFRY WDSSKSVRNL 240
  241 TYGLYRPTFD LADAGEGSKK GISGPKGRFL ATASVMLIST FAFSGVEMTF LASGEAINPR 300
  301 KTIPSATKRT FSIVLISYVF LIFSVGINIY SGDPRLLSYF PGISEKRYEA IIKGTGMDWR 360
  361 LRTNCRGGID YRQISVGTGY SSPWVVALQN FGLCTFASAF NAILIFFTAT AGISSLFSCS 420
  421 RTLYAMSVQR KAPPVFEICS KRGVPYVSVI FSSLFSVIAY IAVDQTAIEN FDVLANVSSA 480
  481 STSIIWMGLN LSFLRFYYAL KQRKDIISRN DSSYPYKSPF QPYLAIYGLV GCSLFVIFMG 540
  541 YPNFIHHFWS TKAFFSAYGG LMFFFISYTA YKVLGTSKIQ RLDQLDMDSG RREMDRTDWT 600
  601 EHSQYLGTYR ERAKKLVTWL I

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	68.657577
Match:	PF00324
Description:	Amino acid permease

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits