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View Structure Prediction Details

Protein: ENT5
Organism: Saccharomyces cerevisiae
Length: 411 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENT5.

Description E-value Query
Range
Subject
Range
ENT5 - Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic betw...
ENT5_YEAST - Epsin-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ENT5 PE=1 SV=1
0.0 [1..411] [1..411]
gi|3894395 - gi|3894395|gb|AAC78608.1| epsin 2a [Homo sapiens]
8.0E-93 [19..378] [6..382]
EPN1_RAT - Epsin-1 OS=Rattus norvegicus GN=Epn1 PE=1 SV=1
1.0E-86 [19..399] [6..384]
lqf-PB, lqf-PD - The gene liquid facets is referred to in FlyBase by the symbol Dmel\lqf (CG8532, FBgn0028582). It is...
3.0E-86 [15..400] [4..381]
SPCC794.11c - ENTH domain protein Ent3
YCTB_SCHPO - ENTH domain-containing protein C794.11c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SP...
1.0E-84 [1..409] [1..401]
EPN3_MOUSE - Epsin-3 OS=Mus musculus GN=Epn3 PE=1 SV=1
4.0E-82 [19..409] [6..415]
gi|147906994, gi... - gi|2072301|gb|AAC60123.1| mitotic phosphoprotein 90 [Xenopus laevis], gi|147906994|ref|NP_001081892....
1.0E-81 [23..380] [1..356]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-81 [9..390] [130..498]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSLSKKIQN LGIHDIRNAA RFAQNVIVQY EPYQIDIRRA TNTDAWGPTP KHLAKVLRNR  60
   61 YQVPLYLMTE YTLKRLVDHI ATRPKNLYEK ARKDYVNYGS EWRVVLKCLV VIEFLLLNVD 120
  121 TGDELNQIRS CLLTHKHILT REIAQFKVKF SNDGKMEIHE RGIRKKGELI LQYLEDSQFL 180
  181 KKERAKNKKN ALKIRQQGES SIYNANQIST SASYDNIDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.68867
Match: 1eyhA_
Description: Epsin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 7.05477548709703 bayes_pls_golite062009
protein binding 2.16467447169895 bayes_pls_golite062009
binding 2.0426788146333 bayes_pls_golite062009
phospholipid binding 1.38798066582556 bayes_pls_golite062009
phosphoinositide binding 1.26458267960741 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [220-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEFDADADGF DSEMDANNVT NFNVPVETEA NSNTRRRSHM EEQRRQRREI LREQIKNKEQ  60
   61 QRKRKQQQDS IPDLIDLDDS TSTTNNITID NGNNDNKNNN INSNSDDDDD EFGDFQSETS 120
  121 PDTTAPKTSN SKIDDLLDWD GPKSDTDTTA AAQTSLPFAE KKQQKARPQA TKDKSKGNDA 180
  181 FSDLFSYSKS LV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.0
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle