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View Structure Prediction Details

Protein: SAN1
Organism: Saccharomyces cerevisiae
Length: 610 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAN1.

Description E-value Query
Range
Subject
Range
SAN1 - Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear prote...
SAN1_YEAST - Protein SAN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAN1 PE=1 SV=1
0.0 [1..610] [1..610]
HRD1_SCHPO - ERAD-associated E3 ubiquitin-protein ligase hrd1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 248...
SPBC17D11.02c - synoviolin homolog
2.0E-72 [198..610] [259..669]
gi|19347753 - gi|19347753|gb|AAL86301.1| putative RING-H2 zinc finger protein ATL6 [Arabidopsis thaliana]
5.0E-49 [211..497] [92..383]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-42 [241..547] [1..317]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESGQEQNR GTNTSPNNAE NNNNSNAASG PLNGGAEQTR NITVSIQYSY FTPERLAHLS  60
   61 NISNNDNNEN NSAASGSTIA NGTGPSFGIG NGGHQPDGAL VLSFRDVPAS TPQDRLNSFI 120
  121 SVAAQLAMER FNRLL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRPKGISKDE FDKLPVLQVS DLPKAEGPLC SICYDEYEDE VDSTKAKRKR DSENEEESEG  60
   61 TKKRKDNEGA PLRTTAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.385 0.817 ubiquitin-protein ligase activity d.42.1 POZ domain

Predicted Domain #3
Region A:
Residues: [213-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDSNPSITNA TVVEPPSIPL TEQQRTLNDE ETNPSYKHSP IKLPCGHIFG RECIYKWSRL  60
   61 ENSCPLCRQK ISESVGVQRA AQQDTDEVAA NEAAFERIRR VLYDPTAVNS TNENSSAPSE 120
  121 NTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1chc__
Description: Immediate early protein, IEEHV
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [336-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTVPTIGNA SSGEQMLSRT GFFLVPQNGQ PLHNPVRLPP NDSDRNGVNG PS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [388-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTQNPPSNS GGSNNNQSPR WVPIPLTLFQ FHSPNPNPSA SDSSASPSAA NGPNSNNTSS  60
   61 DATDPHHNRL RAVLDHIFNV AQRGTSDTSA TTAPGAQTVH NQGRNDSSSS DTTQGSSFLE 120
  121 NISRLTGHFT NGSRDNNNDN NHSNDQQRGG STGENNRNNL FSSGVASYRN QNGDVTTVEL 180
  181 RNNNSAAFPP TDENPSQGQG SSSSDTTIHN DVPNDNNEQR SSQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle