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View Structure Prediction Details

Protein: KIN1
Organism: Saccharomyces cerevisiae
Length: 1064 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KIN1.

Description E-value Query
Range
Subject
Range
gi|171787 - gi|171787|gb|AAA34722.1| protein kinase 1
1143.0 [0..1] [1064..1]
par-1 - status:Partially_confirmed UniProt:Q17368 protein_id:CAB54262.2
756.0 [0..13] [1064..18]
gi|114654973 - gi|114654973|ref|XP_001138004.1| PREDICTED: MAP/microtubule affinity-regulating kinase 3 isoform 8 [...
725.0 [0..53] [796..2]
gi|73964119 - gi|73964119|ref|XP_868654.1| PREDICTED: similar to MAP/microtubule affinity-regulating kinase 3 (Cdc...
725.0 [0..53] [796..2]
gi|18448971 - gi|18448971|gb|AAL69982.1|AF465413_1 MAP/microtubule affinity-regulating kinase 3 long isoform [Homo...
722.0 [0..53] [796..2]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDYHVNTAF SMGRGNQQDD GNSESNSMHT QPSTMAPATL RMMGKSPQQQ QQQNTPLMPP  60
   61 ADIKYANNGN SHQAEQKERQ VELEGKSREN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.045757
Match: 1dsyA
Description: C2 domain from protein kinase c (alpha)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [91-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APKPNTTSQS RVSSSQGMPK QFHRKSLGDW EFVETVGAGS MGKVKLAKHR YTNEVCAVKI  60
   61 VNRATKAFLH KEQMLPPPKN EQDVLERQKK LEKEISRDKR TIREASLGQI LYHPHICRLF 120
  121 EMCTLSNHFY MLFEYVSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 448.09691
Match: 1a06A
Description: CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [229-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQLLDYIIQH GSIREHQARK FARGIASALI YLHANNIVHR DLKIENIMIS DSSEIKIIDF  60
   61 GLSNIYDSRK QLHTFCGSLY FAAPELLKAN PYTGPEVDVW SFGVVLFVLV CGKVPFDDEN 120
  121 SSVLHEKIKQ GKVEYPQHLS IEVISLLSKM LVVDPKRRAT LKQVVEHHWM VRGFNGPPPS 180
  181 YLPKRVPLTI EMLDINVLKE MYRLEFIDDV EETRSVLVSI ITDPTYVLLS RQYWTLAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 448.09691
Match: 1a06A
Description: CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [467-553]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KMNAESSDNG NAPNITESFE DPTRAYHPMI SIYYLTSEML DRKHAKIRNQ QQRQSHENIE  60
   61 KLSEIPESVK QRDVEVNTTA MKSEPEA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.908 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1

Predicted Domain #5
Region A:
Residues: [554-937]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLATKDTSVP FTPKNSDGTE PPLHVLIPPR LAMPEQAHTS PTSRKSSDNQ RREMEYALSP  60
   61 TPQGNDYQQF RVPSTTGDPS EKAKFGNIFR KLSQRRKKTI EQTSVNSNNS INKPVQKTHS 120
  121 RAVSDFVPGF AKPSYDSNYT MNEPVKTNDS RGGNKGDFPA LPADAENMVE KQREKQIEED 180
  181 IMKLHDINKQ NNEVAKGSGR EAYAAQKFEG SDDDENHPLP PLNVAKGRKL HPSARAKSVG 240
  241 HARRESLKYM RPPMPSSAYP QQELIDTGFL ESSDDNKSDS LGNVTSQTND SVSVHSVNAH 300
  301 INSPSVEKEL TDEEILQEAS RAPAGSMPSI DFPRSLFLKG FFSVQTTSSK PLPIVRYKIM 360
  361 FVLRKMNIEF KEVKGGFVCM QRFS

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 7.17
Match:
Description: No description for 1i3qA was found.

Predicted Domain #6
Region A:
Residues: [938-1064]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNNVAAKREG TPRSIMPLSH HESIRRQGSN KYSPSSPLTT NSIHQRKTSI TETYGDDKHS  60
   61 GTSLENIHQQ GDGSEGMTTT EKEPIKFEIH IVKVRIVGLA GVHFKKISGN TWLYKELASS 120
  121 ILKELKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle