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View Structure Prediction Details

Protein: TPI1
Organism: Saccharomyces cerevisiae
Length: 248 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPI1.

Description E-value Query
Range
Subject
Range
gi|24119234, gi|... - gi|24119234|ref|NP_705953.1| triosephosphate isomerase 1 [Danio rerio], gi|15149250|gb|AAK85203.1|AF...
0.0 [2..248] [3..248]
gi|12621074, gi|... - gi|538426|gb|AAA42278.1| triosephosphate isomerase, gi|1351280|sp|P48500|TPIS_RAT Triosephosphate is...
0.0 [2..247] [4..248]
TPIS_CHICK - Triosephosphate isomerase OS=Gallus gallus GN=TPI1 PE=1 SV=2
0.0 [1..248] [1..248]
TPI1 - triosephosphate isomerase 1
TPIS_PANTR - Triosephosphate isomerase OS=Pan troglodytes GN=TPI1 PE=2 SV=2
gi|123993147, gi... - gi|124000137|gb|ABM87577.1| triosephosphate isomerase 1 [synthetic construct], gi|123993147|gb|ABM84...
0.0 [2..247] [4..248]
gi|223374 - gi|223374|prf||0801190A isomerase,triosephosphate
TPIS_RABIT - Triosephosphate isomerase OS=Oryctolagus cuniculus GN=TPI1 PE=1 SV=1
0.0 [2..247] [3..247]
TPIS_MACFA - Triosephosphate isomerase OS=Macaca fascicularis GN=TPI1 PE=2 SV=3
TPIS_MACMU - Triosephosphate isomerase OS=Macaca mulatta GN=TPI1 PE=3 SV=2
0.0 [2..247] [4..248]

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Predicted Domain #1
Region A:
Residues: [1-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARTFFVGGN FKLNGSKQSI KEIVERLNTA SIPENVEVVI CPPATYLDYS VSLVKKPQVT  60
   61 VGAQNAYLKA SGAFTGENSV DQIKDVGAKW VILGHSERRS YFHEDDKFIA DKTKFALGQG 120
  121 VGVILCIGET LEEKKAGKTL DVVERQLNAV LEEVKDWTNV VVAYEPVWAI GTGLAATPED 180
  181 AQDIHASIRK FLASKLGDKA ASELRILYGG SANGSNAVTF KDKADVDGFL VGGASLKPEF 240
  241 VDIINSRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1467.39794
Match: 7timA_
Description: Triosephosphate isomerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
triose-phosphate isomerase activity 5.94525596131351 bayes_pls_golite062009
intramolecular oxidoreductase activity 4.11751506069887 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 3.62219160185043 bayes_pls_golite062009
isomerase activity 2.06271139232842 bayes_pls_golite062009
binding 1.80264931081179 bayes_pls_golite062009
catalytic activity 1.7524198174984 bayes_pls_golite062009
protein binding 0.33788557654084 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle