YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM22
Organism:	Saccharomyces cerevisiae
Length:	207 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM22.

Description	E-value	Query Range	Subject Range
TIM22 - Essential core component of the mitochondrial TIM22 complex involved in insertion of polytopic prote... gi\|190405209 - gi\|190405209\|gb\|EDV08476.1\| mitochondrial import inner membrane translocase subunit TIM22 [Saccharom... gi\|207347159 - gi\|207347159\|gb\|EDZ73436.1\| YDL217Cp-like protein [Saccharomyces cerevisiae AWRI1631] TIM22_YEAST - Mitochondrial import inner membrane translocase subunit TIM22 OS=Saccharomyces cerevisiae (strain AT... gi\|151941790 - gi\|151941790\|gb\|EDN60146.1\| translocase of the inner membrane [Saccharomyces cerevisiae YJM789]	3.0E-56	[1..207]	[1..207]
TIM22_NEUCR - Mitochondrial import inner membrane translocase subunit tim-22 OS=Neurospora crassa GN=tim-22 PE=3 S... TIM22_NEUCR - Mitochondrial import inner membrane translocase subunit tim22 OS=Neurospora crassa (strain ATCC 2469...	1.0E-38	[33..194]	[29..188]
CE25820 - status:Confirmed UniProt:Q9NAQ9 protein_id:CAB97233.1	6.0E-37	[16..194]	[62..212]
FBpp0310761, Tim... - The gene Tim17a1 is referred to in FlyBase by the symbol Dmel\Tim17a1 (CG10090, FBgn0038018). It is ...	4.0E-35	[67..190]	[1..126]
gi\|6760457 - gi\|6760457\|gb\|AAF28360.1\|AF223951_1 TIM22 preprotein translocase [Rattus norvegicus]	5.0E-35	[24..194]	[47..190]
TIMM17B - translocase of inner mitochondrial membrane 17 homolog B (yeast) gi\|55662945 - gi\|55662945\|ref\|XP_521050.1\| PREDICTED: similar to Mitochondrial import inner membrane translocase s...	9.0E-35	[68..190]	[3..127]
TI171_ARATH - Mitochondrial import inner membrane translocase subunit TIM17-1 OS=Arabidopsis thaliana GN=TIM17-1 P...	1.0E-34	[64..190]	[1..127]
TI17B_MOUSE - Mitochondrial import inner membrane translocase subunit Tim17-B OS=Mus musculus GN=Timm17b PE=1 SV=1	2.0E-34	[68..190]	[3..127]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYTGFGLEQ ISPAQKKPYN ELTPEEQGER GAEMIMNFMT SCPGKSVVSG VTGFALGGVL  60
   61 GLFMASMAYD TPLHTPTPAN TAATATAGNI GVGGISRTVQ QISDLPFRQQ MKLQFTDMGK 120
  121 KSYSSAKNFG YIGMIYAGVE CVIESLRAKN DIYNGVTAGF FTGAGLAYKA GPQAALMGGA 180
  181 GFAAFSAAID LYMKSEDGRP PQNDFKE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	117.79588
Match:	PF02466
Description:	Tim17/Tim22/Tim23 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits