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View Structure Prediction Details

Protein: NOP6
Organism: Saccharomyces cerevisiae
Length: 225 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOP6.

Description E-value Query
Range
Subject
Range
gi|190405205 - gi|190405205|gb|EDV08472.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
NOP6_YEAST - Nucleolar protein 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP6 PE=1 SV=1
gi|151941794 - gi|151941794|gb|EDN60150.1| nucleolar protein [Saccharomyces cerevisiae YJM789]
NOP6 - Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (R...
2.0E-67 [1..225] [1..225]
YGR4_SCHPO - Uncharacterized RNA-binding protein C365.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
SPBC365.04c - RNA-binding protein
2.0E-58 [10..225] [17..233]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.002 [22..122] [103..203]

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Predicted Domain #1
Region A:
Residues: [1-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSEEDKKLT KKQLKAQQFR KSKEEKDQEK DVKKEQAPEG KRPNSAAGND GEEPVKKKRK  60
   61 TRRGRGGKGK NGKKGNRFIV FVGSLPRDIT AVELQNHFKN SSPDQIRLRA DKGIAFLEFD 120
  121 ADKDRTGIQR RMDIALLQHG TLLKEKKINV ELTVGGGGNS QERLEKLKNK NIKLDEERKE 180
  181 RLTKMINDGN QKKIAKTTAT AAQTSGTDNK PVPAGIHPDR AKLLK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.13
Match: 1fj7A
Description: Nucleolin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.32086587430292 bayes_pls_golite062009
binding 2.84652855524974 bayes_pls_golite062009
nucleic acid binding 2.07488701626356 bayes_pls_golite062009
1.23676130179002 bayes_pls_golite062009
structural molecule activity 1.11870738570663 bayes_pls_golite062009
protein binding 0.826837409443725 bayes_pls_golite062009
mRNA binding 0.132944695780323 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle