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View Structure Prediction Details

Protein: UFD2
Organism: Saccharomyces cerevisiae
Length: 961 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UFD2.

Description E-value Query
Range
Subject
Range
UFD2 - Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiq...
0.0 [1..961] [1..961]
UFD2_SCHPO - Ubiquitin conjugation factor E4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ufd2 PE=2 ...
ufd2 - ubiquitin-protein ligase E4
0.0 [8..961] [89..1010]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [8..961] [10..931]
gi|14582754, gi|... - gi|62740189|gb|AAH93696.1| Ubiquitination factor E4B [Homo sapiens], gi|56203372|emb|CAI21860.1| ubi...
0.0 [49..954] [290..1171]
gi|10442023, gi|... - gi|11968158|ref|NP_071305.1| ubiquitination factor E4B [Mus musculus], gi|10442023|gb|AAG17287.1|AF2...
0.0 [49..954] [290..1171]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAIEDILQI TTDPSDTRGY SLLKSEEVPQ GSTLGVDFID TLLLYQLTEN EKLDKPFEYL  60
   61 NDCFRRNQQQ KRITKNKPNA ESLHSTFQEI DRLVIGYGVV ASQIENFCMN GAFINYITGI 120
  121 VSNVNSYTDF LSQIIQRAIL EGTALDLLNA VFPTLLEYCN KHVSHFDLNE SVIYNNVLTI 180
  181 FELFVTFKPI AEIFTK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [197-669]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDGFFADYSC KPQDFERKTI LGPILSLSPI EAAVAIRNYG DNLLRSKQQT AMIHESLQAE  60
   61 HKVVIDRLFF IVDKLVRGSL NSRTDMISYF AHIANKNHLR RADHPPFKEL SSNGFMSNIT 120
  121 LLLVRFSQPF LDISYKKIDK IDANYFNNPS LFIDLSGETR LNSDFKEADA FYDKNRKTAD 180
  181 SKPNFISDCF FLTLTYLHYG LGGTLSFEEK MGSEIKALKE EIEKVKKIAA NHDVFARFIT 240
  241 AQLSKMEKAL KTTESLRFAL QGFFAHRSLQ LEVFDFICGA STFLIRVVDP EHEFPFKQIK 300
  301 LPLIPDQIGV ENVDNADFLR AHAPVPFKYY PEFVVEGPVN YSLYISKYQT SPIFRNPRLG 360
  361 SFVEFTTMVL RCPELVSNPH LKGKLVQLLS VGAMPLTDNS PGFMMDIFEH DELVNKNLLY 420
  421 ALLDFYVIVE KTGSSSQFYD KFNSRYSISI ILEELYYKIP SYKNQLIWQS QNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [670-886]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADFFVRFDAR MLNDLTFLLD EGLSNLAEVH NIQNELDNRA RGAPPTREEE DKELQTRLAS  60
   61 ASRQAKSSCG LADKSMKLFE IYSKDIPAAF VTPEIVYRLA SMLNYNLESL VGPKCGELKV 120
  121 KDPQSYSFNP KDLLKALTTV YINLSEQSEF ISAVAKDERS FNRNLFVRAV DILGRKTGLA 180
  181 SPEFIEKLLN FANKAEEQRK ADEEEDLEYG DVPDEFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [887-961]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPLMYTIMKD PVILPASKMN IDRSTIKAHL LSDSTDPFNR MPLKLEDVTP NEELRQKILC  60
   61 FKKQKKEEAK HKASE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1jm7B_
Description: bard1 RING domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle