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View Structure Prediction Details

Protein: UFD2
Organism: Saccharomyces cerevisiae
Length: 961 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UFD2.

Description E-value Query
Range
Subject
Range
UFD2 - Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiq...
0.0 [1..961] [1..961]
UFD2_SCHPO - Ubiquitin conjugation factor E4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ufd2 PE=2 ...
ufd2 - ubiquitin-protein ligase E4
0.0 [8..961] [89..1010]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [8..961] [10..931]
gi|14582754, gi|... - gi|62740189|gb|AAH93696.1| Ubiquitination factor E4B [Homo sapiens], gi|56203372|emb|CAI21860.1| ubi...
0.0 [49..954] [290..1171]
gi|10442023, gi|... - gi|11968158|ref|NP_071305.1| ubiquitination factor E4B [Mus musculus], gi|10442023|gb|AAG17287.1|AF2...
0.0 [49..954] [290..1171]

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Predicted Domain #1
Region A:
Residues: [1-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAIEDILQI TTDPSDTRGY SLLKSEEVPQ GSTLGVDFID TLLLYQLTEN EKLDKPFEYL  60
   61 NDCFRRNQQQ KRITKNKPNA ESLHSTFQEI DRLVIGYGVV ASQIENFCMN GAFINYITGI 120
  121 VSNVNSYTDF LSQIIQRAIL EGTALDLLNA VFPTLLEYCN KHVSHFDLNE SVIYNNVLTI 180
  181 FELFVTFKPI AEIFTK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.391 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.538 N/A N/A a.47.2 t-snare proteins
View Download 0.560 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.382 N/A N/A a.111.1 Acid phosphatase/Vanadium-dependent haloperoxidase
View Download 0.589 N/A N/A a.118.7 14-3-3 protein
View Download 0.382 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.374 N/A N/A a.1.1 Globin-like
View Download 0.368 N/A N/A a.1.1 Globin-like
View Download 0.339 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.312 N/A N/A a.47.1 STAT
View Download 0.307 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.285 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.284 N/A N/A a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.281 N/A N/A a.118.1 ARM repeat
View Download 0.278 N/A N/A a.130.1 Chorismate mutase II
View Download 0.275 N/A N/A a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.271 N/A N/A a.24.3 Cytochromes
View Download 0.253 N/A N/A a.126.1 Serum albumin-like
View Download 0.225 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.223 N/A N/A a.63.1 Apolipophorin-III
View Download 0.223 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.217 N/A N/A a.1.1 Globin-like
View Download 0.212 N/A N/A a.75.1 Ribosomal protein S7
View Download 0.206 N/A N/A a.126.1 Serum albumin-like
View Download 0.205 N/A N/A a.124.1 Phospholipase C/P1 nuclease
View Download 0.204 N/A N/A a.116.1 GTPase activation domain, GAP
View Download 0.203 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like

Predicted Domain #2
Region A:
Residues: [197-669]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDGFFADYSC KPQDFERKTI LGPILSLSPI EAAVAIRNYG DNLLRSKQQT AMIHESLQAE  60
   61 HKVVIDRLFF IVDKLVRGSL NSRTDMISYF AHIANKNHLR RADHPPFKEL SSNGFMSNIT 120
  121 LLLVRFSQPF LDISYKKIDK IDANYFNNPS LFIDLSGETR LNSDFKEADA FYDKNRKTAD 180
  181 SKPNFISDCF FLTLTYLHYG LGGTLSFEEK MGSEIKALKE EIEKVKKIAA NHDVFARFIT 240
  241 AQLSKMEKAL KTTESLRFAL QGFFAHRSLQ LEVFDFICGA STFLIRVVDP EHEFPFKQIK 300
  301 LPLIPDQIGV ENVDNADFLR AHAPVPFKYY PEFVVEGPVN YSLYISKYQT SPIFRNPRLG 360
  361 SFVEFTTMVL RCPELVSNPH LKGKLVQLLS VGAMPLTDNS PGFMMDIFEH DELVNKNLLY 420
  421 ALLDFYVIVE KTGSSSQFYD KFNSRYSISI ILEELYYKIP SYKNQLIWQS QNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [670-886]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADFFVRFDAR MLNDLTFLLD EGLSNLAEVH NIQNELDNRA RGAPPTREEE DKELQTRLAS  60
   61 ASRQAKSSCG LADKSMKLFE IYSKDIPAAF VTPEIVYRLA SMLNYNLESL VGPKCGELKV 120
  121 KDPQSYSFNP KDLLKALTTV YINLSEQSEF ISAVAKDERS FNRNLFVRAV DILGRKTGLA 180
  181 SPEFIEKLLN FANKAEEQRK ADEEEDLEYG DVPDEFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [887-961]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPLMYTIMKD PVILPASKMN IDRSTIKAHL LSDSTDPFNR MPLKLEDVTP NEELRQKILC  60
   61 FKKQKKEEAK HKASE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1jm7B_
Description: bard1 RING domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle