YRC Public Data Repository - Protein Structure Prediction

Protein:	ATG20
Organism:	Saccharomyces cerevisiae
Length:	640 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG20.

Description	E-value	Query Range	Subject Range
ATG20 - Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for en... ATG20_YEAST - Autophagy-related protein 20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG20 PE=1 ...	7.0E-96	[1..640]	[1..640]
gi\|14250231, gi\|... - ref\|NP_659210.1\| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi\|14250231\|gb...	2.0E-76	[202..635]	[1117..1582]
gi\|2351219 - gi\|2351219\|dbj\|BAA22067.1\| myosin heavy chain [Cyprinus carpio]	4.0E-72	[202..638]	[1109..1577]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1	1.0E-71	[127..638]	[1031..1581]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult	2.0E-71	[127..635]	[1032..1578]
gi\|15384839 - gi\|15384839\|emb\|CAC59753.1\| myosin heavy chain [Paracirrhites forsteri]	5.0E-71	[184..635]	[1087..1576]
gi\|45383668, gi\|... - gi\|9800486\|gb\|AAF99314.1\|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi\|45383668\|r...	8.0E-71	[202..638]	[1118..1586]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLNDVQEN AKLNSETRNT GKAEPPHGTT EYVAEAEISK NGVGSPKKSP KKGKVGKGDN  60
   61 NKVETELVHT ALLEKDNPFM EEGPTGFTKS ALLEIPGMRS HNLKNPNEDY EDDSEGLLPL 120
  121 NQESNAETCR TSLSGSINSM NGETSASEEP SVSNRKK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [158-518]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SARIHILEAK RVSEGQGRAY IAYVIQFENS TVQRRYSDFE SLRSILIRLF PMTLIPPIPE  60
   61 KQSIKNYGKS ITGSSSKYLL PSEGSGSVDL SLSVIHASVN NSDEKLIRHR IRMLTEFLNK 120
  121 LLTNEEITKT SIITDFLDPN NHNWHEFVNS SSTFSSLPKS ILQCNPLDPT NTTRIHAMLP 180
  181 IPGSSSQLLL NKESNDKKMD KERSKSFTNI EQDYKQYENL LDNGIYKYNR RTTKTYHDLK 240
  241 SDYNEIGEVF AQFAHEQAQV GELAEQLSYL SNAFSGSSIS LEKLVGRLYY NINEPLNESV 300
  301 HMATSARELI KYRKLKYLQN EMIKKSLNSK RAQLEKLEAQ NNEYKDVDKI IDNEMSKSHT 360
  361 I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.221849
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [519-640]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLERPNNNTG SGGKSYGGKL FNGFNKLASM VKDSVKYQET DPHTASINLK KEIEQLSESL  60
   61 EVTENDLEVI SKVIKNDQLP KFSKEREVDL SEILKHYSRY MRNYARQNLE IWKEVKRHQD 120
  121 FA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.821	0.025	protein targeting to vacuole	a.24.4	Hemerythrin

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits