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View Structure Prediction Details

Protein: ATG20
Organism: Saccharomyces cerevisiae
Length: 640 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG20.

Description E-value Query
Range
Subject
Range
ATG20 - Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for en...
ATG20_YEAST - Autophagy-related protein 20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG20 PE=1 ...
7.0E-96 [1..640] [1..640]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
2.0E-76 [202..635] [1117..1582]
gi|2351219 - gi|2351219|dbj|BAA22067.1| myosin heavy chain [Cyprinus carpio]
4.0E-72 [202..638] [1109..1577]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
1.0E-71 [127..638] [1031..1581]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
2.0E-71 [127..635] [1032..1578]
gi|15384839 - gi|15384839|emb|CAC59753.1| myosin heavy chain [Paracirrhites forsteri]
5.0E-71 [184..635] [1087..1576]
gi|45383668, gi|... - gi|9800486|gb|AAF99314.1|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi|45383668|r...
8.0E-71 [202..638] [1118..1586]

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Predicted Domain #1
Region A:
Residues: [1-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLNDVQEN AKLNSETRNT GKAEPPHGTT EYVAEAEISK NGVGSPKKSP KKGKVGKGDN  60
   61 NKVETELVHT ALLEKDNPFM EEGPTGFTKS ALLEIPGMRS HNLKNPNEDY EDDSEGLLPL 120
  121 NQESNAETCR TSLSGSINSM NGETSASEEP SVSNRKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [158-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SARIHILEAK RVSEGQGRAY IAYVIQFENS TVQRRYSDFE SLRSILIRLF PMTLIPPIPE  60
   61 KQSIKNYGKS ITGSSSKYLL PSEGSGSVDL SLSVIHASVN NSDEKLIRHR IRMLTEFLNK 120
  121 LLTNEEITKT SIITDFLDPN NHNWHEFVNS SSTFSSLPKS ILQCNPLDPT NTTRIHAMLP 180
  181 IPGSSSQLLL NKESNDKKMD KERSKSFTNI EQDYKQYENL LDNGIYKYNR RTTKTYHDLK 240
  241 SDYNEIGEVF AQFAHEQAQV GELAEQLSYL SNAFSGSSIS LEKLVGRLYY NINEPLNESV 300
  301 HMATSARELI KYRKLKYLQN EMIKKSLNSK RAQLEKLEAQ NNEYKDVDKI IDNEMSKSHT 360
  361 I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [519-640]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLERPNNNTG SGGKSYGGKL FNGFNKLASM VKDSVKYQET DPHTASINLK KEIEQLSESL  60
   61 EVTENDLEVI SKVIKNDQLP KFSKEREVDL SEILKHYSRY MRNYARQNLE IWKEVKRHQD 120
  121 FA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.607 0.028 protein targeting to vacuole a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.821 0.025 protein targeting to vacuole a.24.4 Hemerythrin
View Download 0.506 0.023 protein targeting to vacuole a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.579 0.022 protein targeting to vacuole a.144.1 PABC (PABP) domain
View Download 0.451 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.436 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.402 N/A N/A a.24.12 Outer surface protein C (OspC)
View Download 0.378 N/A N/A a.74.1 Cyclin-like
View Download 0.374 N/A N/A a.29.2 Bromodomain
View Download 0.339 N/A N/A a.47.2 t-snare proteins
View Download 0.336 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.312 N/A N/A a.25.1 Ferritin-like
View Download 0.271 N/A N/A a.7.1 Spectrin repeat
View Download 0.269 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.267 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.266 N/A N/A a.24.3 Cytochromes
View Download 0.258 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.257 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.255 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.253 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.253 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.249 N/A N/A a.158.1 F-box domain
View Download 0.245 N/A N/A a.1.1 Globin-like
View Download 0.244 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.243 N/A N/A d.44.1 Fe,Mn superoxide dismutase (SOD), C-terminal domain
View Download 0.242 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.239 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.238 N/A N/A a.21.1 HMG-box
View Download 0.235 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.235 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.234 N/A N/A b.43.5 Riboflavin kinase
View Download 0.230 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.230 N/A N/A a.91.1 Regulator of G-protein signalling, RGS
View Download 0.223 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.222 N/A N/A a.39.1 EF-hand
View Download 0.218 N/A N/A a.19.1 Fertilization protein
View Download 0.216 N/A N/A d.58.26 GHMP Kinase, C-terminal domain
View Download 0.216 N/A N/A d.58.47 Hypothetical protein VC0424
View Download 0.216 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.214 N/A N/A a.4.12 TrpR-like
View Download 0.211 N/A N/A a.4.1 Homeodomain-like
View Download 0.208 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.206 N/A N/A a.7.4 Smac/diablo
View Download 0.202 N/A N/A c.23.1 CheY-like


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